P31463 (YIDZ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
HTH-type transcriptional regulator YidZ

Gene names

Name:	yidZ
Ordered Locus Names:	b3711, JW3689

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Involved in anaerobic NO protection. HAMAP-Rule MF_01607
Sequence similarities	Contains 1 HTH lysR-type DNA-binding domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Ligand	DNA-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from mutant phenotype Ref.4. Source: EcoCyc
Molecular_function	DNA binding Inferred from electronic annotation. Source: HAMAP sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 319	319	HTH-type transcriptional regulator YidZ HAMAP-Rule MF_01607		PRO_0000105801
Regions
	Domain	8 – 65	58	HTH lysR-type
	DNA binding	25 – 44	20	H-T-H motif By similarity

Sequences

	Sequence		Length	Mass (Da)
	P31463 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: 8E49CF88397EB125	FASTA	319	36,882
	10 20 30 40 50 60 MKKSITTLDL NLLLCLQLLM QERSVTKAAK RINVTPSAVS KSLAKLRAWF DDPLFVNSPL 70 80 90 100 110 120 GLSPTPLMVS MEQNLAEWMQ MSNLLLDKPH HQTPRGLKFE LAAESPLMMI MLNALSKQIY 130 140 150 160 170 180 QRYPQATIKL RNWDYDSLDA ITRGEVDIGF SGRESHPRSR ELLSSLPLAI DYEVLFSDVP 190 200 210 220 230 240 CVWLRKDHPA LHQTWNLDTF LRYPHISICW EQSDTWALDN VLQELGRERT IAMSLPEFEQ 250 260 270 280 290 300 SLFMAAQPDN LLLATAPRYC QYYNQLHQLP LVALPLPFDE SQQKKLEVPF TLLWHKRNSH 310 NPKIVWLRET IKNLYASMA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R. Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide." Justino M.C., Vicente J.B., Teixeira M., Saraiva L.M. J. Biol. Chem. 280:2636-2643(2005) [PubMed] [Europe PMC] [Abstract] Cited for: CHARACTERIZATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L10328 Genomic DNA. Translation: AAA62062.1. U00096 Genomic DNA. Translation: AAC76734.1. AP009048 Genomic DNA. Translation: BAE77579.1.
PIR	H65173.
RefSeq	NP_418167.1. NC_000913.2. YP_491720.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P31463.
SMR	P31463. Positions 99-316.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12458N.
IntAct	P31463. 2 interactions.
MINT	MINT-1257535.
STRING	511145.b3711.
Protocols and materials databases
DNASU	948227.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC76734; AAC76734; b3711. BAE77579; BAE77579; BAE77579.
GeneID	12933603. 948227.
KEGG	ecj:Y75_p3459. eco:b3711.
PATRIC	32122917. VBIEscCol129921_3834.
Organism-specific databases
EchoBASE	EB1672.
EcoGene	EG11721. yidZ.
Phylogenomic databases
eggNOG	COG0583.
HOGENOM	HOG000103694.
OMA	MEQDLAD.
ProtClustDB	PRK10216.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11721-MONOMER. ECOL316407:JW3689-MONOMER.
Gene expression databases
Genevestigator	P31463.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
HAMAP	MF_01607. HTH-type_YidZ.
InterPro	IPR005119. LysR_subst-bd. IPR000847. Tscrpt_reg_HTH_LysR. IPR023746. Tscrpt_reg_YidZ. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00126. HTH_1. 1 hit. PF03466. LysR_substrate. 1 hit. [Graphical view]
PROSITE	PS50931. HTH_LYSR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YIDZ_ECOLI

Accession

Primary (citable) accession number: P31463
Secondary accession number(s): Q2M827

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 1, 2013
This is version 103 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program