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P31460

- DGOR_ECOLI

UniProt

P31460 - DGOR_ECOLI

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Protein
Galactonate operon transcriptional repressor
Gene
dgoR, yidW, b4479, JW5627
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi31 – 5020H-T-H motif Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7790-MONOMER.
ECOL316407:JW5627-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactonate operon transcriptional repressor
Gene namesi
Name:dgoR
Synonyms:yidW
Ordered Locus Names:b4479, JW5627
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG11718. dgoR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 229229Galactonate operon transcriptional repressor
PRO_0000050621Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriP31460.

Interactioni

Protein-protein interaction databases

DIPiDIP-9435N.
STRINGi511145.b4479.

Structurei

3D structure databases

ProteinModelPortaliP31460.
SMRiP31460. Positions 4-150.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7171HTH gntR-type
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2186.
HOGENOMiHOG000273996.
OMAiIHEDIVI.
OrthoDBiEOG6JQH1G.
PhylomeDBiP31460.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiIPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
[Graphical view]
PRINTSiPR00035. HTHGNTR.
SMARTiSM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
[Graphical view]
SUPFAMiSSF48008. SSF48008. 1 hit.
PROSITEiPS50949. HTH_GNTR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31460-1 [UniParc]FASTAAdd to Basket

« Hide

MTLNKTDRIV ITLGKQIVHG KYVPGSPLPA EAELCEEFAT SRNIIREVFR    50
SLMAKRLIEM KRYRGAFVAP RNQWNYLDTD VLQWVLENDY DPRLISAMSE 100
VRNLVEPAIA RWAAERATSS DLAQIESALN EMIANNQDRE AFNEADIRYH 150
EAVLQSVHNP VLQQLSIAIS SLQRAVFERT WMGDEANMPQ TLQEHKALFD 200
AIRHQDGDAA EQAALTMIAS STRRLKEIT 229
Length:229
Mass (Da):26,080
Last modified:October 11, 2004 - v4
Checksum:iEE41742299285B8F
GO

Sequence cautioni

The sequence AAA62046.1 differs from that shown. Reason: Frameshift at position 174.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1122RW → VA in AAA62046. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L10328 Genomic DNA. Translation: AAA62046.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48199.1.
AP009048 Genomic DNA. Translation: BAE77599.1.
RefSeqiYP_026239.1. NC_000913.3.
YP_491740.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAT48199; AAT48199; b4479.
BAE77599; BAE77599; BAE77599.
GeneIDi12934379.
2847767.
KEGGiecj:Y75_p3478.
eco:b4479.
PATRICi32122885. VBIEscCol129921_3818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L10328 Genomic DNA. Translation: AAA62046.1 . Frameshift.
U00096 Genomic DNA. Translation: AAT48199.1 .
AP009048 Genomic DNA. Translation: BAE77599.1 .
RefSeqi YP_026239.1. NC_000913.3.
YP_491740.1. NC_007779.1.

3D structure databases

ProteinModelPortali P31460.
SMRi P31460. Positions 4-150.
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-9435N.
STRINGi 511145.b4479.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAT48199 ; AAT48199 ; b4479 .
BAE77599 ; BAE77599 ; BAE77599 .
GeneIDi 12934379.
2847767.
KEGGi ecj:Y75_p3478.
eco:b4479.
PATRICi 32122885. VBIEscCol129921_3818.

Organism-specific databases

EchoBASEi EB1669.
EcoGenei EG11718. dgoR.

Phylogenomic databases

eggNOGi COG2186.
HOGENOMi HOG000273996.
OMAi IHEDIVI.
OrthoDBi EOG6JQH1G.
PhylomeDBi P31460.

Enzyme and pathway databases

BioCyci EcoCyc:G7790-MONOMER.
ECOL316407:JW5627-MONOMER.

Miscellaneous databases

PROi P31460.

Gene expression databases

Genevestigatori P31460.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProi IPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
[Graphical view ]
PRINTSi PR00035. HTHGNTR.
SMARTi SM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
[Graphical view ]
SUPFAMi SSF48008. SSF48008. 1 hit.
PROSITEi PS50949. HTH_GNTR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
    Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
    Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: SEQUENCE REVISION.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiDGOR_ECOLI
AccessioniPrimary (citable) accession number: P31460
Secondary accession number(s): O32529
, P76735, Q2M807, Q6BF15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: June 11, 2014
This is version 115 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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