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P31460 (DGOR_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 113. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Galactonate operon transcriptional repressor
Gene names
Name:dgoR
Synonyms:yidW
Ordered Locus Names:b4479, JW5627
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length229 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.

Sequence similarities

Contains 1 HTH gntR-type DNA-binding domain.

Sequence caution

The sequence AAA62046.1 differs from that shown. Reason: Frameshift at position 174.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   LigandDNA-binding
   Molecular functionRepressor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 229229Galactonate operon transcriptional repressor
PRO_0000050621

Regions

Domain1 – 7171HTH gntR-type
DNA binding31 – 5020H-T-H motif Potential

Experimental info

Sequence conflict111 – 1122RW → VA in AAA62046. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P31460 [UniParc].

Last modified October 11, 2004. Version 4.
Checksum: EE41742299285B8F

FASTA22926,080
        10         20         30         40         50         60 
MTLNKTDRIV ITLGKQIVHG KYVPGSPLPA EAELCEEFAT SRNIIREVFR SLMAKRLIEM 

        70         80         90        100        110        120 
KRYRGAFVAP RNQWNYLDTD VLQWVLENDY DPRLISAMSE VRNLVEPAIA RWAAERATSS 

       130        140        150        160        170        180 
DLAQIESALN EMIANNQDRE AFNEADIRYH EAVLQSVHNP VLQQLSIAIS SLQRAVFERT 

       190        200        210        220 
WMGDEANMPQ TLQEHKALFD AIRHQDGDAA EQAALTMIAS STRRLKEIT 

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005."
Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R., Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T., Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H., Thomson N.R., Wishart D., Wanner B.L.
Nucleic Acids Res. 34:1-9(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.
[4]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L10328 Genomic DNA. Translation: AAA62046.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48199.1.
AP009048 Genomic DNA. Translation: BAE77599.1.
RefSeqYP_026239.1. NC_000913.3.
YP_491740.1. NC_007779.1.

3D structure databases

ProteinModelPortalP31460.
SMRP31460. Positions 2-227.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-9435N.
STRING511145.b4479.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAT48199; AAT48199; b4479.
BAE77599; BAE77599; BAE77599.
GeneID12934379.
2847767.
KEGGecj:Y75_p3478.
eco:b4479.
PATRIC32122885. VBIEscCol129921_3818.

Organism-specific databases

EchoBASEEB1669.
EcoGeneEG11718. dgoR.

Phylogenomic databases

eggNOGCOG2186.
HOGENOMHOG000273996.
OMAAAHEIND.
OrthoDBEOG6JQH1G.
PhylomeDBP31460.
ProtClustDBCLSK894832.

Enzyme and pathway databases

BioCycEcoCyc:G7790-MONOMER.
ECOL316407:JW5627-MONOMER.

Gene expression databases

GenevestigatorP31460.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProIPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
[Graphical view]
PRINTSPR00035. HTHGNTR.
SMARTSM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
[Graphical view]
SUPFAMSSF48008. SSF48008. 1 hit.
PROSITEPS50949. HTH_GNTR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP31460.

Entry information

Entry nameDGOR_ECOLI
AccessionPrimary (citable) accession number: P31460
Secondary accession number(s): O32529 expand/collapse secondary AC list , P76735, Q2M807, Q6BF15
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 113 of the entry and version 4 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene