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Protein

Galactonate operon transcriptional repressor

Gene

dgoR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi31 – 50H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G7790-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactonate operon transcriptional repressor
Gene namesi
Name:dgoR
Synonyms:yidW
Ordered Locus Names:b4479, JW5627
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11718. dgoR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000506211 – 229Galactonate operon transcriptional repressorAdd BLAST229

Proteomic databases

PaxDbiP31460.
PRIDEiP31460.

Interactioni

Protein-protein interaction databases

BioGridi4263373. 13 interactors.
DIPiDIP-9435N.
STRINGi511145.b4479.

Structurei

3D structure databases

ProteinModelPortaliP31460.
SMRiP31460.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 71HTH gntR-typePROSITE-ProRule annotationAdd BLAST71

Phylogenomic databases

eggNOGiENOG4105EMF. Bacteria.
COG2186. LUCA.
HOGENOMiHOG000273996.
InParanoidiP31460.
KOiK19776.
PhylomeDBiP31460.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiView protein in InterPro
IPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
PRINTSiPR00035. HTHGNTR.
SMARTiView protein in SMART
SM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF48008. SSF48008. 1 hit.
PROSITEiView protein in PROSITE
PS50949. HTH_GNTR. 1 hit.

Sequencei

Sequence statusi: Complete.

P31460-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLNKTDRIV ITLGKQIVHG KYVPGSPLPA EAELCEEFAT SRNIIREVFR
60 70 80 90 100
SLMAKRLIEM KRYRGAFVAP RNQWNYLDTD VLQWVLENDY DPRLISAMSE
110 120 130 140 150
VRNLVEPAIA RWAAERATSS DLAQIESALN EMIANNQDRE AFNEADIRYH
160 170 180 190 200
EAVLQSVHNP VLQQLSIAIS SLQRAVFERT WMGDEANMPQ TLQEHKALFD
210 220
AIRHQDGDAA EQAALTMIAS STRRLKEIT
Length:229
Mass (Da):26,080
Last modified:October 11, 2004 - v4
Checksum:iEE41742299285B8F
GO

Sequence cautioni

The sequence AAA62046 differs from that shown. Reason: Frameshift at position 174.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti111 – 112RW → VA in AAA62046 (PubMed:7686882).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62046.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48199.1.
AP009048 Genomic DNA. Translation: BAE77599.1.
RefSeqiWP_000174305.1. NZ_LN832404.1.
YP_026239.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48199; AAT48199; b4479.
BAE77599; BAE77599; BAE77599.
GeneIDi2847767.
KEGGiecj:JW5627.
eco:b4479.
PATRICifig|1411691.4.peg.3008.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62046.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48199.1.
AP009048 Genomic DNA. Translation: BAE77599.1.
RefSeqiWP_000174305.1. NZ_LN832404.1.
YP_026239.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP31460.
SMRiP31460.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263373. 13 interactors.
DIPiDIP-9435N.
STRINGi511145.b4479.

Proteomic databases

PaxDbiP31460.
PRIDEiP31460.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48199; AAT48199; b4479.
BAE77599; BAE77599; BAE77599.
GeneIDi2847767.
KEGGiecj:JW5627.
eco:b4479.
PATRICifig|1411691.4.peg.3008.

Organism-specific databases

EchoBASEiEB1669.
EcoGeneiEG11718. dgoR.

Phylogenomic databases

eggNOGiENOG4105EMF. Bacteria.
COG2186. LUCA.
HOGENOMiHOG000273996.
InParanoidiP31460.
KOiK19776.
PhylomeDBiP31460.

Enzyme and pathway databases

BioCyciEcoCyc:G7790-MONOMER.

Miscellaneous databases

PROiPR:P31460.

Family and domain databases

CDDicd07377. WHTH_GntR. 1 hit.
Gene3Di1.10.10.10. 1 hit.
1.20.120.530. 1 hit.
InterProiView protein in InterPro
IPR011711. GntR_C.
IPR008920. TF_FadR/GntR_C.
IPR000524. Tscrpt_reg_HTH_GntR.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF07729. FCD. 1 hit.
PF00392. GntR. 1 hit.
PRINTSiPR00035. HTHGNTR.
SMARTiView protein in SMART
SM00895. FCD. 1 hit.
SM00345. HTH_GNTR. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF48008. SSF48008. 1 hit.
PROSITEiView protein in PROSITE
PS50949. HTH_GNTR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiDGOR_ECOLI
AccessioniPrimary (citable) accession number: P31460
Secondary accession number(s): O32529
, P76735, Q2M807, Q6BF15
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: June 7, 2017
This is version 132 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.