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P31460

- DGOR_ECOLI

UniProt

P31460 - DGOR_ECOLI

Protein

Galactonate operon transcriptional repressor

Gene

dgoR

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 116 (01 Oct 2014)
      Sequence version 4 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi31 – 5020H-T-H motifPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    GO - Biological processi

    1. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Repressor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Enzyme and pathway databases

    BioCyciEcoCyc:G7790-MONOMER.
    ECOL316407:JW5627-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Galactonate operon transcriptional repressor
    Gene namesi
    Name:dgoR
    Synonyms:yidW
    Ordered Locus Names:b4479, JW5627
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11718. dgoR.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229Galactonate operon transcriptional repressorPRO_0000050621Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriP31460.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-9435N.
    STRINGi511145.b4479.

    Structurei

    3D structure databases

    ProteinModelPortaliP31460.
    SMRiP31460. Positions 4-150.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 7171HTH gntR-typePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Contains 1 HTH gntR-type DNA-binding domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG2186.
    HOGENOMiHOG000273996.
    OMAiIHEDIVI.
    OrthoDBiEOG6JQH1G.
    PhylomeDBiP31460.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    1.20.120.530. 1 hit.
    InterProiIPR011711. GntR_C.
    IPR008920. TF_FadR/GntR_C.
    IPR000524. Tscrpt_reg_HTH_GntR.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF07729. FCD. 1 hit.
    PF00392. GntR. 1 hit.
    [Graphical view]
    PRINTSiPR00035. HTHGNTR.
    SMARTiSM00895. FCD. 1 hit.
    SM00345. HTH_GNTR. 1 hit.
    [Graphical view]
    SUPFAMiSSF48008. SSF48008. 1 hit.
    PROSITEiPS50949. HTH_GNTR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P31460-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTLNKTDRIV ITLGKQIVHG KYVPGSPLPA EAELCEEFAT SRNIIREVFR    50
    SLMAKRLIEM KRYRGAFVAP RNQWNYLDTD VLQWVLENDY DPRLISAMSE 100
    VRNLVEPAIA RWAAERATSS DLAQIESALN EMIANNQDRE AFNEADIRYH 150
    EAVLQSVHNP VLQQLSIAIS SLQRAVFERT WMGDEANMPQ TLQEHKALFD 200
    AIRHQDGDAA EQAALTMIAS STRRLKEIT 229
    Length:229
    Mass (Da):26,080
    Last modified:October 11, 2004 - v4
    Checksum:iEE41742299285B8F
    GO

    Sequence cautioni

    The sequence AAA62046.1 differs from that shown. Reason: Frameshift at position 174.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti111 – 1122RW → VA in AAA62046. (PubMed:7686882)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10328 Genomic DNA. Translation: AAA62046.1. Frameshift.
    U00096 Genomic DNA. Translation: AAT48199.1.
    AP009048 Genomic DNA. Translation: BAE77599.1.
    RefSeqiYP_026239.1. NC_000913.3.
    YP_491740.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAT48199; AAT48199; b4479.
    BAE77599; BAE77599; BAE77599.
    GeneIDi12934379.
    2847767.
    KEGGiecj:Y75_p3478.
    eco:b4479.
    PATRICi32122885. VBIEscCol129921_3818.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L10328 Genomic DNA. Translation: AAA62046.1 . Frameshift.
    U00096 Genomic DNA. Translation: AAT48199.1 .
    AP009048 Genomic DNA. Translation: BAE77599.1 .
    RefSeqi YP_026239.1. NC_000913.3.
    YP_491740.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P31460.
    SMRi P31460. Positions 4-150.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-9435N.
    STRINGi 511145.b4479.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT48199 ; AAT48199 ; b4479 .
    BAE77599 ; BAE77599 ; BAE77599 .
    GeneIDi 12934379.
    2847767.
    KEGGi ecj:Y75_p3478.
    eco:b4479.
    PATRICi 32122885. VBIEscCol129921_3818.

    Organism-specific databases

    EchoBASEi EB1669.
    EcoGenei EG11718. dgoR.

    Phylogenomic databases

    eggNOGi COG2186.
    HOGENOMi HOG000273996.
    OMAi IHEDIVI.
    OrthoDBi EOG6JQH1G.
    PhylomeDBi P31460.

    Enzyme and pathway databases

    BioCyci EcoCyc:G7790-MONOMER.
    ECOL316407:JW5627-MONOMER.

    Miscellaneous databases

    PROi P31460.

    Gene expression databases

    Genevestigatori P31460.

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    1.20.120.530. 1 hit.
    InterProi IPR011711. GntR_C.
    IPR008920. TF_FadR/GntR_C.
    IPR000524. Tscrpt_reg_HTH_GntR.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF07729. FCD. 1 hit.
    PF00392. GntR. 1 hit.
    [Graphical view ]
    PRINTSi PR00035. HTHGNTR.
    SMARTi SM00895. FCD. 1 hit.
    SM00345. HTH_GNTR. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48008. SSF48008. 1 hit.
    PROSITEi PS50949. HTH_GNTR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
      Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
      Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    3. Cited for: SEQUENCE REVISION.
    4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiDGOR_ECOLI
    AccessioniPrimary (citable) accession number: P31460
    Secondary accession number(s): O32529
    , P76735, Q2M807, Q6BF15
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1993
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 116 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3