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Protein

Uncharacterized symporter YidK

Gene

yidK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Sodium transport, Symport, Transport

Keywords - Ligandi

Sodium

Enzyme and pathway databases

BioCyciEcoCyc:YIDK-MONOMER.
ECOL316407:JW3655-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized symporter YidK
Gene namesi
Name:yidK
Ordered Locus Names:b3679, JW3655
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318 Componenti: Chromosome UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11706. yidK.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 33CytoplasmicSequence Analysis
Transmembranei4 – 2421HelicalSequence AnalysisAdd
BLAST
Topological domaini25 – 7450PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei75 – 9521HelicalSequence AnalysisAdd
BLAST
Topological domaini96 – 11823CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei119 – 13921HelicalSequence AnalysisAdd
BLAST
Topological domaini140 – 16223PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei163 – 18321HelicalSequence AnalysisAdd
BLAST
Topological domaini184 – 1918CytoplasmicSequence Analysis
Transmembranei192 – 21221HelicalSequence AnalysisAdd
BLAST
Topological domaini213 – 24028PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei241 – 26121HelicalSequence AnalysisAdd
BLAST
Topological domaini262 – 28322CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei284 – 30421HelicalSequence AnalysisAdd
BLAST
Topological domaini305 – 32420PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei325 – 34521HelicalSequence AnalysisAdd
BLAST
Topological domaini346 – 38035CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei381 – 40121HelicalSequence AnalysisAdd
BLAST
Topological domaini402 – 41514PeriplasmicSequence AnalysisAdd
BLAST
Transmembranei416 – 43621HelicalSequence AnalysisAdd
BLAST
Topological domaini437 – 4371CytoplasmicSequence Analysis
Transmembranei438 – 45821HelicalSequence AnalysisAdd
BLAST
Topological domaini459 – 4602PeriplasmicSequence Analysis
Transmembranei461 – 48121HelicalSequence AnalysisAdd
BLAST
Topological domaini482 – 50524CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei506 – 52621HelicalSequence AnalysisAdd
BLAST
Topological domaini527 – 5326PeriplasmicSequence Analysis
Transmembranei533 – 55321HelicalSequence AnalysisAdd
BLAST
Topological domaini554 – 57118CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 571571Uncharacterized symporter YidKPRO_0000105406Add
BLAST

Interactioni

Protein-protein interaction databases

DIPiDIP-12450N.
IntActiP31448. 5 interactions.
MINTiMINT-1256907.
STRINGi511145.b3679.

Structurei

3D structure databases

ProteinModelPortaliP31448.
SMRiP31448. Positions 41-456.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG4146.
HOGENOMiHOG000025424.
InParanoidiP31448.
KOiK03307.
OMAiLAQFGGY.
OrthoDBiEOG6MSS23.
PhylomeDBiP31448.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
IPR019900. Na/solute_symporter_subgr.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00813. sss. 1 hit.
PROSITEiPS00456. NA_SOLUT_SYMP_1. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31448-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSLQILSFV GFTLLVAVIT WWKVRKTDTG SQQGYFLAGR SLKAPVIAAS
60 70 80 90 100
LMLTNLSTEQ LVGLSGQAYK SGMSVMGWEV TSAVTLIFLA LIFLPRYLKR
110 120 130 140 150
GIATIPDFLE ERYDKTTRII IDFCFLIATG VCFLPIVLYS GALALNSLFH
160 170 180 190 200
VGESLQISHG AAIWLLVILL GLAGILYAVI GGLRAMAVAD SINGIGLVIG
210 220 230 240 250
GLMVPVFGLI AMGKGSFMQG IEQLTTVHAE KLNSIGGPTD PLPIGAAFTG
260 270 280 290 300
LILVNTFYWC TNQGIVQRTL ASKSLAEGQK GALLTAVLKM LDPLVLVLPG
310 320 330 340 350
LIAFHLYQDL PKADMAYPTL VNNVLPVPMV GFFGAVLFGA VISTFNGFLN
360 370 380 390 400
SASTLFSMGI YRRIINQNAE PQQLVTVGRK FGFFIAIVSV LVAPWIANAP
410 420 430 440 450
QGLYSWMKQL NGIYNVPLVT IIIMGFFFPR IPALAAKVAM GIGIISYITI
460 470 480 490 500
NYLVKFDFHF LYVLACTFCI NVVVMLVIGF IKPRATPFTF KDAFAVDMKP
510 520 530 540 550
WKNVKIASIG ILFAMIGVYA GLAEFGGYGT RWLAMISYFI AAVVIVYLIF
560 570
DSWRHRHDPA VTFTPDGKDS L
Length:571
Mass (Da):62,085
Last modified:July 1, 1993 - v1
Checksum:i486AB89A6A2EACCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62031.1.
U00096 Genomic DNA. Translation: AAC76702.1.
AP009048 Genomic DNA. Translation: BAE77614.1.
PIRiH65169.
RefSeqiNP_418135.1. NC_000913.3.
WP_001087145.1. NZ_CP010445.1.

Genome annotation databases

EnsemblBacteriaiAAC76702; AAC76702; b3679.
BAE77614; BAE77614; BAE77614.
GeneIDi948185.
KEGGieco:b3679.
PATRICi32122849. VBIEscCol129921_3800.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62031.1.
U00096 Genomic DNA. Translation: AAC76702.1.
AP009048 Genomic DNA. Translation: BAE77614.1.
PIRiH65169.
RefSeqiNP_418135.1. NC_000913.3.
WP_001087145.1. NZ_CP010445.1.

3D structure databases

ProteinModelPortaliP31448.
SMRiP31448. Positions 41-456.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-12450N.
IntActiP31448. 5 interactions.
MINTiMINT-1256907.
STRINGi511145.b3679.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76702; AAC76702; b3679.
BAE77614; BAE77614; BAE77614.
GeneIDi948185.
KEGGieco:b3679.
PATRICi32122849. VBIEscCol129921_3800.

Organism-specific databases

EchoBASEiEB1657.
EcoGeneiEG11706. yidK.

Phylogenomic databases

eggNOGiCOG4146.
HOGENOMiHOG000025424.
InParanoidiP31448.
KOiK03307.
OMAiLAQFGGY.
OrthoDBiEOG6MSS23.
PhylomeDBiP31448.

Enzyme and pathway databases

BioCyciEcoCyc:YIDK-MONOMER.
ECOL316407:JW3655-MONOMER.

Miscellaneous databases

PROiP31448.

Family and domain databases

InterProiIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
IPR019900. Na/solute_symporter_subgr.
[Graphical view]
PANTHERiPTHR11819. PTHR11819. 1 hit.
PfamiPF00474. SSF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00813. sss. 1 hit.
PROSITEiPS00456. NA_SOLUT_SYMP_1. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
    Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
    Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYIDK_ECOLI
AccessioniPrimary (citable) accession number: P31448
Secondary accession number(s): Q2M7Z2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: July 22, 2015
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.