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P31448 (YIDK_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 117. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized symporter YidK
Gene names
Name:yidK
Ordered Locus Names:b3679, JW3655
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length571 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Ontologies

Keywords
   Biological processIon transport
Sodium transport
Symport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   LigandSodium
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processsodium ion transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsymporter activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 571571Uncharacterized symporter YidK
PRO_0000105406

Regions

Topological domain1 – 33Cytoplasmic Potential
Transmembrane4 – 2421Helical; Potential
Topological domain25 – 7450Periplasmic Potential
Transmembrane75 – 9521Helical; Potential
Topological domain96 – 11823Cytoplasmic Potential
Transmembrane119 – 13921Helical; Potential
Topological domain140 – 16223Periplasmic Potential
Transmembrane163 – 18321Helical; Potential
Topological domain184 – 1918Cytoplasmic Potential
Transmembrane192 – 21221Helical; Potential
Topological domain213 – 24028Periplasmic Potential
Transmembrane241 – 26121Helical; Potential
Topological domain262 – 28322Cytoplasmic Potential
Transmembrane284 – 30421Helical; Potential
Topological domain305 – 32420Periplasmic Potential
Transmembrane325 – 34521Helical; Potential
Topological domain346 – 38035Cytoplasmic Potential
Transmembrane381 – 40121Helical; Potential
Topological domain402 – 41514Periplasmic Potential
Transmembrane416 – 43621Helical; Potential
Topological domain4371Cytoplasmic Potential
Transmembrane438 – 45821Helical; Potential
Topological domain459 – 4602Periplasmic Potential
Transmembrane461 – 48121Helical; Potential
Topological domain482 – 50524Cytoplasmic Potential
Transmembrane506 – 52621Helical; Potential
Topological domain527 – 5326Periplasmic Potential
Transmembrane533 – 55321Helical; Potential
Topological domain554 – 57118Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
P31448 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: 486AB89A6A2EACCF

FASTA57162,085
        10         20         30         40         50         60 
MNSLQILSFV GFTLLVAVIT WWKVRKTDTG SQQGYFLAGR SLKAPVIAAS LMLTNLSTEQ 

        70         80         90        100        110        120 
LVGLSGQAYK SGMSVMGWEV TSAVTLIFLA LIFLPRYLKR GIATIPDFLE ERYDKTTRII 

       130        140        150        160        170        180 
IDFCFLIATG VCFLPIVLYS GALALNSLFH VGESLQISHG AAIWLLVILL GLAGILYAVI 

       190        200        210        220        230        240 
GGLRAMAVAD SINGIGLVIG GLMVPVFGLI AMGKGSFMQG IEQLTTVHAE KLNSIGGPTD 

       250        260        270        280        290        300 
PLPIGAAFTG LILVNTFYWC TNQGIVQRTL ASKSLAEGQK GALLTAVLKM LDPLVLVLPG 

       310        320        330        340        350        360 
LIAFHLYQDL PKADMAYPTL VNNVLPVPMV GFFGAVLFGA VISTFNGFLN SASTLFSMGI 

       370        380        390        400        410        420 
YRRIINQNAE PQQLVTVGRK FGFFIAIVSV LVAPWIANAP QGLYSWMKQL NGIYNVPLVT 

       430        440        450        460        470        480 
IIIMGFFFPR IPALAAKVAM GIGIISYITI NYLVKFDFHF LYVLACTFCI NVVVMLVIGF 

       490        500        510        520        530        540 
IKPRATPFTF KDAFAVDMKP WKNVKIASIG ILFAMIGVYA GLAEFGGYGT RWLAMISYFI 

       550        560        570 
AAVVIVYLIF DSWRHRHDPA VTFTPDGKDS L 

« Hide

References

[1]"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication."
Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.
Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Global topology analysis of the Escherichia coli inner membrane proteome."
Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L10328 Genomic DNA. Translation: AAA62031.1.
U00096 Genomic DNA. Translation: AAC76702.1.
AP009048 Genomic DNA. Translation: BAE77614.1.
PIRH65169.
RefSeqNP_418135.1. NC_000913.3.
YP_491755.1. NC_007779.1.

3D structure databases

ProteinModelPortalP31448.
SMRP31448. Positions 41-456.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-12450N.
IntActP31448. 5 interactions.
MINTMINT-1256907.
STRING511145.b3679.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC76702; AAC76702; b3679.
BAE77614; BAE77614; BAE77614.
GeneID12932458.
948185.
KEGGecj:Y75_p3495.
eco:b3679.
PATRIC32122849. VBIEscCol129921_3800.

Organism-specific databases

EchoBASEEB1657.
EcoGeneEG11706. yidK.

Phylogenomic databases

eggNOGCOG4146.
HOGENOMHOG000025424.
KOK03307.
OMAMLMIGFI.
OrthoDBEOG6MSS23.
PhylomeDBP31448.

Enzyme and pathway databases

BioCycEcoCyc:YIDK-MONOMER.
ECOL316407:JW3655-MONOMER.

Gene expression databases

GenevestigatorP31448.

Family and domain databases

InterProIPR001734. Na/solute_symporter.
IPR018212. Na/solute_symporter_CS.
IPR019900. Na/solute_symporter_subgr.
[Graphical view]
PANTHERPTHR11819. PTHR11819. 1 hit.
PfamPF00474. SSF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00813. sss. 1 hit.
PROSITEPS00456. NA_SOLUT_SYMP_1. 1 hit.
PS50283. NA_SOLUT_SYMP_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP31448.

Entry information

Entry nameYIDK_ECOLI
AccessionPrimary (citable) accession number: P31448
Secondary accession number(s): Q2M7Z2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: June 11, 2014
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene