Uncharacterized symporter YidK - Escherichia coli (strain K12)

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P31448 (YIDK_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 108. History...

Clusters with 100%, 90%, 50% identity |

Documents (2) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Uncharacterized symporter YidK

Gene names

Name:	yidK
Ordered Locus Names:	b3679, JW3655

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	571 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. [View classification]

Ontologies

Keywords
Biological process	Ion transport Sodium transport Symport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	Sodium
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	sodium ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	symporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 571

571

Uncharacterized symporter YidK

PRO_0000105406

Regions

Topological domain

1 – 3

Cytoplasmic Potential

Transmembrane

4 – 24

Helical; Potential

Topological domain

25 – 74

Periplasmic Potential

Transmembrane

75 – 95

Helical; Potential

Topological domain

96 – 118

Cytoplasmic Potential

Transmembrane

119 – 139

Helical; Potential

Topological domain

140 – 162

Periplasmic Potential

Transmembrane

163 – 183

Helical; Potential

Topological domain

184 – 191

Cytoplasmic Potential

Transmembrane

192 – 212

Helical; Potential

Topological domain

213 – 240

Periplasmic Potential

Transmembrane

241 – 261

Helical; Potential

Topological domain

262 – 283

Cytoplasmic Potential

Transmembrane

284 – 304

Helical; Potential

Topological domain

305 – 324

Periplasmic Potential

Transmembrane

325 – 345

Helical; Potential

Topological domain

346 – 380

Cytoplasmic Potential

Transmembrane

381 – 401

Helical; Potential

Topological domain

402 – 415

Periplasmic Potential

Transmembrane

416 – 436

Helical; Potential

Topological domain

437

Cytoplasmic Potential

Transmembrane

438 – 458

Helical; Potential

Topological domain

459 – 460

Periplasmic Potential

Transmembrane

461 – 481

Helical; Potential

Topological domain

482 – 505

Cytoplasmic Potential

Transmembrane

506 – 526

Helical; Potential

Topological domain

527 – 532

Periplasmic Potential

Transmembrane

533 – 553

Helical; Potential

Topological domain

554 – 571

Cytoplasmic Potential

Sequences

Sequence

Length

Mass (Da)

Tools

P31448 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: 486AB89A6A2EACCF
Show »

FASTA

571

62,085

        10         20         30         40         50         60 
MNSLQILSFV GFTLLVAVIT WWKVRKTDTG SQQGYFLAGR SLKAPVIAAS LMLTNLSTEQ 

        70         80         90        100        110        120 
LVGLSGQAYK SGMSVMGWEV TSAVTLIFLA LIFLPRYLKR GIATIPDFLE ERYDKTTRII 

       130        140        150        160        170        180 
IDFCFLIATG VCFLPIVLYS GALALNSLFH VGESLQISHG AAIWLLVILL GLAGILYAVI 

       190        200        210        220        230        240 
GGLRAMAVAD SINGIGLVIG GLMVPVFGLI AMGKGSFMQG IEQLTTVHAE KLNSIGGPTD 

       250        260        270        280        290        300 
PLPIGAAFTG LILVNTFYWC TNQGIVQRTL ASKSLAEGQK GALLTAVLKM LDPLVLVLPG 

       310        320        330        340        350        360 
LIAFHLYQDL PKADMAYPTL VNNVLPVPMV GFFGAVLFGA VISTFNGFLN SASTLFSMGI 

       370        380        390        400        410        420 
YRRIINQNAE PQQLVTVGRK FGFFIAIVSV LVAPWIANAP QGLYSWMKQL NGIYNVPLVT 

       430        440        450        460        470        480 
IIIMGFFFPR IPALAAKVAM GIGIISYITI NYLVKFDFHF LYVLACTFCI NVVVMLVIGF 

       490        500        510        520        530        540 
IKPRATPFTF KDAFAVDMKP WKNVKIASIG ILFAMIGVYA GLAEFGGYGT RWLAMISYFI 

       550        560        570 
AAVVIVYLIF DSWRHRHDPA VTFTPDGKDS L

« Hide

References

[1]	"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R. Genomics 16:551-561(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: K12 / MG1655 / ATCC 47076.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L10328 Genomic DNA. Translation: AAA62031.1. U00096 Genomic DNA. Translation: AAC76702.1. AP009048 Genomic DNA. Translation: BAE77614.1.
PIR	H65169.
RefSeq	NP_418135.1. NC_000913.2. YP_491755.1. NC_007779.1.
3D structure databases
ProteinModelPortal	P31448.
SMR	P31448. Positions 41-456.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-12450N.
IntAct	P31448. 5 interactions.
MINT	MINT-1256907.
STRING	511145.b3679.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC76702; AAC76702; b3679. BAE77614; BAE77614; BAE77614.
GeneID	12932458. 948185.
KEGG	ecj:Y75_p3495. eco:b3679.
PATRIC	32122849. VBIEscCol129921_3800.
Organism-specific databases
EchoBASE	EB1657.
EcoGene	EG11706. yidK.
Phylogenomic databases
eggNOG	COG4146.
HOGENOM	HOG000025424.
KO	K03307.
OMA	NVVVMLM.
ProtClustDB	PRK10484.
Enzyme and pathway databases
BioCyc	EcoCyc:YIDK-MONOMER. ECOL316407:JW3655-MONOMER.
Gene expression databases
Genevestigator	P31448.
Family and domain databases
InterPro	IPR001734. Na/solute_symporter. IPR018212. Na/solute_symporter_CS. IPR019900. Na/solute_symporter_subgr. [Graphical view]
PANTHER	PTHR11819. PTHR11819. 1 hit.
Pfam	PF00474. SSF. 1 hit. [Graphical view]
TIGRFAMs	TIGR00813. sss. 1 hit.
PROSITE	PS00456. NA_SOLUT_SYMP_1. 1 hit. PS00457. NA_SOLUT_SYMP_2. False negative. PS50283. NA_SOLUT_SYMP_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YIDK_ECOLI

Accession

Primary (citable) accession number: P31448
Secondary accession number(s): Q2M7Z2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	May 1, 2013
This is version 108 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

Entry information

Relevant documents