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Protein

Inner membrane symporter YicJ

Gene

yicJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Symport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:YICJ-MONOMER.
ECOL316407:JW5939-MONOMER.

Protein family/group databases

TCDBi2.A.2.3.4. the glycoside-pentoside-hexuronide (gph):cation symporter family.

Names & Taxonomyi

Protein namesi
Recommended name:
Inner membrane symporter YicJ
Gene namesi
Name:yicJ
Ordered Locus Names:b3657, JW5939
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11686. yicJ.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 11PeriplasmicSequence analysisAdd BLAST11
Transmembranei12 – 32HelicalSequence analysisAdd BLAST21
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21
Topological domaini54 – 80PeriplasmicSequence analysisAdd BLAST27
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Topological domaini102 – 116CytoplasmicSequence analysisAdd BLAST15
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Topological domaini138 – 152PeriplasmicSequence analysisAdd BLAST15
Transmembranei153 – 173HelicalSequence analysisAdd BLAST21
Topological domaini174 – 181CytoplasmicSequence analysis8
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Topological domaini203 – 248PeriplasmicSequence analysisAdd BLAST46
Transmembranei249 – 269HelicalSequence analysisAdd BLAST21
Topological domaini270 – 288CytoplasmicSequence analysisAdd BLAST19
Transmembranei289 – 309HelicalSequence analysisAdd BLAST21
Topological domaini310PeriplasmicSequence analysis1
Transmembranei311 – 331HelicalSequence analysisAdd BLAST21
Topological domaini332 – 366CytoplasmicSequence analysisAdd BLAST35
Transmembranei367 – 387HelicalSequence analysisAdd BLAST21
Topological domaini388 – 403PeriplasmicSequence analysisAdd BLAST16
Transmembranei404 – 424HelicalSequence analysisAdd BLAST21
Topological domaini425 – 460CytoplasmicSequence analysisAdd BLAST36

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001707661 – 460Inner membrane symporter YicJAdd BLAST460

Proteomic databases

PaxDbiP31435.
PRIDEiP31435.

Interactioni

Protein-protein interaction databases

BioGridi4261976. 162 interactors.
STRINGi511145.b3657.

Structurei

3D structure databases

ProteinModelPortaliP31435.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CT4. Bacteria.
COG2211. LUCA.
HOGENOMiHOG000222022.
InParanoidiP31435.
KOiK03292.
OMAiWWTNAIL.
PhylomeDBiP31435.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR001927. Na/Gal_symport.
IPR018043. Na/Gal_symport_CS.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00792. gph. 1 hit.
PROSITEiPS00872. NA_GALACTOSIDE_SYMP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31435-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSEVLSVKE KIGYGMGDAA SHIIFDNVML YMMFFYTDIF GIPAGFVGTM
60 70 80 90 100
FLVARALDAI SDPCMGLLAD RTRSRWGKFR PWVLFGALPF GIVCVLAYST
110 120 130 140 150
PDLSMNGKMI YAAITYTLLT LLYTVVNIPY CALGGVITND PTQRISLQSW
160 170 180 190 200
RFVLATAGGM LSTVLMMPLV NLIGGDNKPL GFQGGIAVLS VVAFMMLAFC
210 220 230 240 250
FFTTKERVEA PPTTTSMRED LRDIWQNDQW RIVGLLTIFN ILAVCVRGGA
260 270 280 290 300
MMYYVTWILG TPEVFVAFLT TYCVGNLIGS ALAKPLTDWK CKVTIFWWTN
310 320 330 340 350
ALLAVISLAM FFVPMQASIT MFVFIFVIGV LHQLVTPIQW VMMSDTVDYG
360 370 380 390 400
EWCNGKRLTG ISFAGTLFVL KLGLAFGGAL IGWMLAYGGY DAAEKAQNSA
410 420 430 440 450
TISIIIALFT IVPAICYLLS AIIAKRYYSL TTHNLKTVME QLAQGKRRCQ
460
QQFTSQEVQN
Length:460
Mass (Da):50,948
Last modified:July 15, 1998 - v2
Checksum:iBBDDC8BC7D2D2B13
GO

Sequence cautioni

The sequence AAA62010 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62010.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76681.2.
AP009048 Genomic DNA. Translation: BAE77636.1.
RefSeqiNP_418114.4. NC_000913.3.
WP_000834439.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76681; AAC76681; b3657.
BAE77636; BAE77636; BAE77636.
GeneIDi948168.
KEGGiecj:JW5939.
eco:b3657.
PATRICi32122801. VBIEscCol129921_3777.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA. Translation: AAA62010.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76681.2.
AP009048 Genomic DNA. Translation: BAE77636.1.
RefSeqiNP_418114.4. NC_000913.3.
WP_000834439.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP31435.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261976. 162 interactors.
STRINGi511145.b3657.

Protein family/group databases

TCDBi2.A.2.3.4. the glycoside-pentoside-hexuronide (gph):cation symporter family.

Proteomic databases

PaxDbiP31435.
PRIDEiP31435.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76681; AAC76681; b3657.
BAE77636; BAE77636; BAE77636.
GeneIDi948168.
KEGGiecj:JW5939.
eco:b3657.
PATRICi32122801. VBIEscCol129921_3777.

Organism-specific databases

EchoBASEiEB1637.
EcoGeneiEG11686. yicJ.

Phylogenomic databases

eggNOGiENOG4105CT4. Bacteria.
COG2211. LUCA.
HOGENOMiHOG000222022.
InParanoidiP31435.
KOiK03292.
OMAiWWTNAIL.
PhylomeDBiP31435.

Enzyme and pathway databases

BioCyciEcoCyc:YICJ-MONOMER.
ECOL316407:JW5939-MONOMER.

Miscellaneous databases

PROiP31435.

Family and domain databases

InterProiIPR020846. MFS_dom.
IPR001927. Na/Gal_symport.
IPR018043. Na/Gal_symport_CS.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00792. gph. 1 hit.
PROSITEiPS00872. NA_GALACTOSIDE_SYMP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYICJ_ECOLI
AccessioniPrimary (citable) accession number: P31435
Secondary accession number(s): P76724, Q2M7X0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 15, 1998
Last modified: November 2, 2016
This is version 123 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.