##gff-version 3
P31415	UniProtKB	Signal peptide	1	34	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
P31415	UniProtKB	Chain	35	396	.	.	.	ID=PRO_0000004212;Note=Calsequestrin-1	
P31415	UniProtKB	Modified residue	43	43	.	.	.	Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19633	
P31415	UniProtKB	Modified residue	81	81	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19633	
P31415	UniProtKB	Modified residue	124	124	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19633	
P31415	UniProtKB	Modified residue	216	216	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P19633	
P31415	UniProtKB	Glycosylation	350	350	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P31415	UniProtKB	Natural variant	44	44	.	.	.	ID=VAR_079704;Note=In TAM1%3B increased calcium-dependent susceptibility to proteolytic degradation%3B decreased calcium-dependent aggregation%3B decreased calcium-dependent polymerization%3B no effect on subcellular localization%3B no effect on the subcellular localization of STIM1%3B decreased calcium content of intracellular stores%3B loss of the ability to inhibit store-operated calcium entry (SOCE) activity. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28895244;Dbxref=dbSNP:rs140253806,PMID:28895244	
P31415	UniProtKB	Natural variant	103	103	.	.	.	ID=VAR_079705;Note=In TAM1%3B increased calcium-dependent susceptibility to proteolytic degradation%3B decreased calcium-dependent aggregation%3B decreased calcium-dependent polymerization%3B no effect on subcellular localization%3B no effect on the subcellular localization of STIM1%3B decreased calcium content of intracellular stores%3B no effect of the ability to inhibit store-operated calcium entry (SOCE) activity%3B muscle fibers with the mutation have significantly decreased calcium-dependent sensitivity to caffeine. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28895244;Dbxref=PMID:28895244	
P31415	UniProtKB	Natural variant	140	140	.	.	.	ID=VAR_053021;Note=Y->F;Dbxref=dbSNP:rs34489853	
P31415	UniProtKB	Natural variant	244	244	.	.	.	ID=VAR_073337;Note=In VMCQA%3B no effect on calcium-dependent susceptibility to proteolytic degradation%3B increased calcium-dependent aggregation%3B causes impaired polymerization of the protein%3B no effect on subcellular localization%3B decreased calcium content of sarcoplasmic reticulum stores%3B reduced sarcoplasmic reticulum calcium release during excitation-contraction coupling. D->G;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:25116801,ECO:0000269|PubMed:26136523,ECO:0000269|PubMed:27196359,ECO:0000269|PubMed:28895244;Dbxref=dbSNP:rs730882052,PMID:25116801,PMID:26136523,PMID:27196359,PMID:28895244	
P31415	UniProtKB	Natural variant	385	385	.	.	.	ID=VAR_079706;Note=In TAM1%3B no effect on calcium-dependent susceptibility to proteolytic degradation%3B increased moderately calcium-dependent aggregation%3B increased moderately calcium-dependent polymerization%3B no effect on subcellular localization%3B no effect on the subcellular localization of STIM1%3B decreased calcium content of intracellular stores%3B loss of the ability to inhibit store-operated calcium entry (SOCE) activity. I->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:28895244;Dbxref=dbSNP:rs371278891,PMID:28895244	
P31415	UniProtKB	Sequence conflict	356	357	.	.	.	Note=SV->RL;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P31415	UniProtKB	Beta strand	49	51	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:3UOM	
P31415	UniProtKB	Turn	54	56	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	57	63	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	65	72	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	79	98	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Turn	99	103	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	104	110	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Turn	111	114	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	115	121	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	129	133	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	136	140	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	146	157	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	160	163	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	167	175	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	181	185	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	189	191	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRE	
P31415	UniProtKB	Helix	192	204	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Turn	205	207	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	210	213	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	216	222	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	229	232	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	243	246	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	249	258	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	263	266	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	269	271	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	272	276	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	283	288	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	291	293	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRE	
P31415	UniProtKB	Helix	294	309	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Turn	310	312	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	318	321	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	323	325	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	327	329	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Helix	330	337	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	341	343	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRE	
P31415	UniProtKB	Beta strand	345	350	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Turn	351	353	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	356	358	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG	
P31415	UniProtKB	Beta strand	363	365	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRE	
P31415	UniProtKB	Helix	370	381	.	.	.	Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:5CRG