P31397 (MAP3_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 95.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Pheromone M-factor receptor | ||||
| Gene names |
| ||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome] | ||||
| Taxonomic identifier | 284812 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › ![]() |
Protein attributes
| Sequence length | 365 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at transcript level |
General annotation (Comments)
| Function | Receptor for the peptide pheromone M-factor, a mating factor of S.pombe. Pheromone signaling is essential for initiation of meiosis in S.pombe; M-factor signaling alone may be sufficient. |
| Subcellular location | |
| Induction | By at least 3 types of regulation: the mating-type of the cell, nutritional conditions and pheromone signaling. |
| Sequence similarities | Belongs to the G-protein coupled receptor 4 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Pheromone response |
| Cellular component | Membrane |
| Domain | Transmembrane Transmembrane helix |
| Molecular function | G-protein coupled receptor Receptor Transducer |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | negative regulation of transcription from RNA polymerase II promoter Inferred from mutant phenotype PubMed 7975894. Source: PomBase positive regulation of meiosisInferred by curator. Source: PomBase response to pheromoneInferred from electronic annotation. Source: UniProtKB-KW signal transduction involved in conjugation with cellular fusionInferred by curator. Source: PomBase |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW nucleusInferred from direct assay PubMed 16823372. Source: PomBase plasma membraneInferred by curator. Source: PomBase |
| Molecular_function | mating-type factor pheromone receptor activity Inferred from experiment Ref.1. Source: PomBase |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 365 | 365 | Pheromone M-factor receptor | PRO_0000195075 | |||||
Regions | |||||||||
| Transmembrane | 7 – 24 | 18 | Helical; Name=1; Potential | ||||||
| Transmembrane | 31 – 54 | 24 | Helical; Name=2; Potential | ||||||
| Transmembrane | 73 – 100 | 28 | Helical; Name=3; Potential | ||||||
| Transmembrane | 116 – 133 | 18 | Helical; Name=4; Potential | ||||||
| Transmembrane | 155 – 182 | 28 | Helical; Name=5; Potential | ||||||
| Transmembrane | 204 – 226 | 23 | Helical; Name=6; Potential | ||||||
| Transmembrane | 265 – 283 | 19 | Helical; Name=7; Potential | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Schizosaccharomyces pombe map3+ encodes the putative M-factor receptor." Tanaka K., Davey J., Imai Y., Yamamoto M. Mol. Cell. Biol. 13:80-88(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ST711. |
| [2] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | D10933 Genomic DNA. Translation: BAA01727.1. CU329670 Genomic DNA. Translation: CAA93308.1. |
| PIR | A48105. |
| RefSeq | NP_593942.1. NM_001019370.2. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 4896.SPAC3F10.10c-1. |
Protein family/group databases | |
| GPCRDB | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPAC3F10.10c.1; SPAC3F10.10c.1:pep; SPAC3F10.10c. |
| GeneID | 2542271. |
| KEGG | spo:SPAC3F10.10c. |
Organism-specific databases | |
| PomBase | SPAC3F10.10c. |
Phylogenomic databases | |
| eggNOG | NOG71865. |
| KO | K04627. |
| OMA | CKSIEST. |
| OrthoDB | EOG4CC79F. |
Family and domain databases | |
| InterPro | IPR001499. GPCR_STE3. [Graphical view] |
| Pfam | PF02076. STE3. 1 hit. [Graphical view] |
| PRINTS | PR00899. GPCRSTE3. |
| ProtoNet | Search... |
Other | |
| NextBio | 20803335. |
Entry information
| Entry name | MAP3_SCHPO | ||||||||
| Accession | Primary (citable) accession number: P31397 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| 7-transmembrane G-linked receptors List of 7-transmembrane G-linked receptor entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with
