Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P31386

- ATS1_YEAST

UniProt

P31386 - ATS1_YEAST

Protein

Protein ATS1

Gene

ATS1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 115 (01 Oct 2014)
      Sequence version 2 (27 Jul 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May participate in regulatory interactions between microtubules and the cell cycle.

    GO - Biological processi

    1. budding cell bud growth Source: SGD
    2. microtubule-based process Source: SGD
    3. microtubule cytoskeleton organization Source: SGD
    4. tRNA wobble uridine modification Source: SGD

    Enzyme and pathway databases

    BioCyciYEAST:G3O-28832-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein ATS1
    Alternative name(s):
    Alpha-tubulin suppressor 1
    Gene namesi
    Name:ATS1
    Ordered Locus Names:YAL020C
    ORF Names:FUN28, YAL006
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome I

    Organism-specific databases

    CYGDiYAL020c.
    SGDiS000000018. ATS1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: SGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 333333Protein ATS1PRO_0000206648Add
    BLAST

    Proteomic databases

    MaxQBiP31386.
    PaxDbiP31386.
    PeptideAtlasiP31386.

    Expressioni

    Gene expression databases

    GenevestigatoriP31386.

    Interactioni

    Protein-protein interaction databases

    BioGridi31746. 91 interactions.
    IntActiP31386. 2 interactions.
    MINTiMINT-2786397.
    STRINGi4932.YAL020C.

    Structurei

    3D structure databases

    ProteinModelPortaliP31386.
    SMRiP31386. Positions 4-189, 240-307.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati1 – 5353RCC1 1Add
    BLAST
    Repeati55 – 10450RCC1 2Add
    BLAST
    Repeati146 – 19752RCC1 3Add
    BLAST
    Repeati286 – 33348RCC1 4Add
    BLAST

    Sequence similaritiesi

    Contains 4 RCC1 repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG5184.
    HOGENOMiHOG000163478.
    KOiK15462.
    OMAiCRKGQLG.
    OrthoDBiEOG757D8X.

    Family and domain databases

    Gene3Di2.130.10.30. 2 hits.
    InterProiIPR009091. RCC1/BLIP-II.
    IPR000408. Reg_chr_condens.
    [Graphical view]
    PfamiPF00415. RCC1. 1 hit.
    [Graphical view]
    PRINTSiPR00633. RCCNDNSATION.
    SUPFAMiSSF50985. SSF50985. 1 hit.
    PROSITEiPS00626. RCC1_2. 1 hit.
    PS50012. RCC1_3. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P31386-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSCVYAFGSN GQRQLGLGHD EDMDTPQRSV PGDDGAIVRK IACGGNHSVM    50
    LTNDGNLVGC GDNRRGELDS AQALRQVHDW RPVEVPAPVV DVACGWDTTV 100
    IVDADGRVWQ RGGGCYEFTQ QHVPLNSNDE RIAVYGCFQN FVVVQGTRVY 150
    GWGSNTKCQL QEPKSRSLKE PVLVYDTGSV AVDYVAMGKD FMVIVDEGGR 200
    IVHASGRLPT GFELKQQQKR HNLVVLCMWT SIHLWNARLN TVESFGRGTH 250
    SQLFPQERLD FPIVGVATGS EHGILTTANQ EGKSHCYNVY CWGWGEHGNC 300
    GPQKGSQPGL QLVGQYSGKP RVFGGCATTW IVL 333
    Length:333
    Mass (Da):36,467
    Last modified:July 27, 2011 - v2
    Checksum:i3C6F4BE180479096
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti305 – 3051G → A no nucleotide entry (PubMed:8458570)Curated
    Sequence conflicti305 – 3051G → A no nucleotide entry (PubMed:8144453)Curated
    Sequence conflicti305 – 3051G → A in AAC04937. (PubMed:7731988)Curated
    Sequence conflicti305 – 3051G → A no nucleotide entry (PubMed:1561836)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L05146 Genomic DNA. Translation: AAC04937.1.
    BK006935 Genomic DNA. Translation: DAA06968.2.
    PIRiS36714.
    RefSeqiNP_009382.2. NM_001178165.2.

    Genome annotation databases

    EnsemblFungiiYAL020C; YAL020C; YAL020C.
    GeneIDi851213.
    KEGGisce:YAL020C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L05146 Genomic DNA. Translation: AAC04937.1 .
    BK006935 Genomic DNA. Translation: DAA06968.2 .
    PIRi S36714.
    RefSeqi NP_009382.2. NM_001178165.2.

    3D structure databases

    ProteinModelPortali P31386.
    SMRi P31386. Positions 4-189, 240-307.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 31746. 91 interactions.
    IntActi P31386. 2 interactions.
    MINTi MINT-2786397.
    STRINGi 4932.YAL020C.

    Proteomic databases

    MaxQBi P31386.
    PaxDbi P31386.
    PeptideAtlasi P31386.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YAL020C ; YAL020C ; YAL020C .
    GeneIDi 851213.
    KEGGi sce:YAL020C.

    Organism-specific databases

    CYGDi YAL020c.
    SGDi S000000018. ATS1.

    Phylogenomic databases

    eggNOGi COG5184.
    HOGENOMi HOG000163478.
    KOi K15462.
    OMAi CRKGQLG.
    OrthoDBi EOG757D8X.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-28832-MONOMER.

    Miscellaneous databases

    NextBioi 968094.

    Gene expression databases

    Genevestigatori P31386.

    Family and domain databases

    Gene3Di 2.130.10.30. 2 hits.
    InterProi IPR009091. RCC1/BLIP-II.
    IPR000408. Reg_chr_condens.
    [Graphical view ]
    Pfami PF00415. RCC1. 1 hit.
    [Graphical view ]
    PRINTSi PR00633. RCCNDNSATION.
    SUPFAMi SSF50985. SSF50985. 1 hit.
    PROSITEi PS00626. RCC1_2. 1 hit.
    PS50012. RCC1_3. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing of chromosome I from Saccharomyces cerevisiae: analysis of a 32 kb region between the LTE1 and SPO7 genes."
      Ouellette B.F.F., Clark M.W., Keng T., Storms R.K., Zhong W.-W., Zeng B., Fortin N., Delaney S., Barton A.B., Kaback D.B., Bussey H.
      Genome 36:32-42(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    2. "Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUN38-MAK16-SPO7 region."
      Barton A.B., Kaback D.B.
      J. Bacteriol. 176:1872-1880(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 305.
      Strain: ATCC 204508 / S288c.
    5. "Identification of a Saccharomyces cerevisiae homolog of the SNF2 transcriptional regulator in the DNA sequence of an 8.6 kb region in the LTE1-CYS1 interval on the left arm of chromosome I."
      Clark M.W., Zhong W.-W., Keng T., Storms R.K., Barton A.B., Kaback D.B., Bussey H.
      Yeast 8:133-145(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    6. "Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules."
      Kirkpatrick D., Solomon F.
      Genetics 137:381-392(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.

    Entry informationi

    Entry nameiATS1_YEAST
    AccessioniPrimary (citable) accession number: P31386
    Secondary accession number(s): D6VPJ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1993
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 115 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome I
      Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

    External Data

    Dasty 3