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P31386 (ATS1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 114. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein ATS1
Alternative name(s):
Alpha-tubulin suppressor 1
Gene names
Name:ATS1
Ordered Locus Names:YAL020C
ORF Names:FUN28, YAL006
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May participate in regulatory interactions between microtubules and the cell cycle.

Sequence similarities

Contains 4 RCC1 repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 333333Protein ATS1
PRO_0000206648

Regions

Repeat1 – 5353RCC1 1
Repeat55 – 10450RCC1 2
Repeat146 – 19752RCC1 3
Repeat286 – 33348RCC1 4

Experimental info

Sequence conflict3051G → A no nucleotide entry Ref.1
Sequence conflict3051G → A no nucleotide entry Ref.2
Sequence conflict3051G → A in AAC04937. Ref.3
Sequence conflict3051G → A no nucleotide entry Ref.5

Sequences

Sequence LengthMass (Da)Tools
P31386 [UniParc].

Last modified July 27, 2011. Version 2.
Checksum: 3C6F4BE180479096

FASTA33336,467
        10         20         30         40         50         60 
MSCVYAFGSN GQRQLGLGHD EDMDTPQRSV PGDDGAIVRK IACGGNHSVM LTNDGNLVGC 

        70         80         90        100        110        120 
GDNRRGELDS AQALRQVHDW RPVEVPAPVV DVACGWDTTV IVDADGRVWQ RGGGCYEFTQ 

       130        140        150        160        170        180 
QHVPLNSNDE RIAVYGCFQN FVVVQGTRVY GWGSNTKCQL QEPKSRSLKE PVLVYDTGSV 

       190        200        210        220        230        240 
AVDYVAMGKD FMVIVDEGGR IVHASGRLPT GFELKQQQKR HNLVVLCMWT SIHLWNARLN 

       250        260        270        280        290        300 
TVESFGRGTH SQLFPQERLD FPIVGVATGS EHGILTTANQ EGKSHCYNVY CWGWGEHGNC 

       310        320        330 
GPQKGSQPGL QLVGQYSGKP RVFGGCATTW IVL 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing of chromosome I from Saccharomyces cerevisiae: analysis of a 32 kb region between the LTE1 and SPO7 genes."
Ouellette B.F.F., Clark M.W., Keng T., Storms R.K., Zhong W.-W., Zeng B., Fortin N., Delaney S., Barton A.B., Kaback D.B., Bussey H.
Genome 36:32-42(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: analysis of the genes in the FUN38-MAK16-SPO7 region."
Barton A.B., Kaback D.B.
J. Bacteriol. 176:1872-1880(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[3]"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae."
Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K.
Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[4]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION, SEQUENCE REVISION TO 305.
Strain: ATCC 204508 / S288c.
[5]"Identification of a Saccharomyces cerevisiae homolog of the SNF2 transcriptional regulator in the DNA sequence of an 8.6 kb region in the LTE1-CYS1 interval on the left arm of chromosome I."
Clark M.W., Zhong W.-W., Keng T., Storms R.K., Barton A.B., Kaback D.B., Bussey H.
Yeast 8:133-145(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[6]"Overexpression of yeast homologs of the mammalian checkpoint gene RCC1 suppresses the class of alpha-tubulin mutations that arrest with excess microtubules."
Kirkpatrick D., Solomon F.
Genetics 137:381-392(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L05146 Genomic DNA. Translation: AAC04937.1.
BK006935 Genomic DNA. Translation: DAA06968.2.
PIRS36714.
RefSeqNP_009382.2. NM_001178165.2.

3D structure databases

ProteinModelPortalP31386.
SMRP31386. Positions 4-189, 240-307.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31746. 91 interactions.
IntActP31386. 2 interactions.
MINTMINT-2786397.
STRING4932.YAL020C.

Proteomic databases

MaxQBP31386.
PaxDbP31386.
PeptideAtlasP31386.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYAL020C; YAL020C; YAL020C.
GeneID851213.
KEGGsce:YAL020C.

Organism-specific databases

CYGDYAL020c.
SGDS000000018. ATS1.

Phylogenomic databases

eggNOGCOG5184.
HOGENOMHOG000163478.
KOK15462.
OMACRKGQLG.
OrthoDBEOG757D8X.

Enzyme and pathway databases

BioCycYEAST:G3O-28832-MONOMER.

Gene expression databases

GenevestigatorP31386.

Family and domain databases

Gene3D2.130.10.30. 2 hits.
InterProIPR009091. RCC1/BLIP-II.
IPR000408. Reg_chr_condens.
[Graphical view]
PfamPF00415. RCC1. 1 hit.
[Graphical view]
PRINTSPR00633. RCCNDNSATION.
SUPFAMSSF50985. SSF50985. 1 hit.
PROSITEPS00626. RCC1_2. 1 hit.
PS50012. RCC1_3. 4 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio968094.

Entry information

Entry nameATS1_YEAST
AccessionPrimary (citable) accession number: P31386
Secondary accession number(s): D6VPJ8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 27, 2011
Last modified: July 9, 2014
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome I

Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families