Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

POU domain protein 1

Gene

POU1

Organism
Dugesia japonica (Planarian)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi351 – 410HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain protein 1
Short name:
DjPOU1
Gene namesi
Name:POU1
OrganismiDugesia japonica (Planarian)
Taxonomic identifieri6161 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesRhabditophoraSeriataTricladidaContinenticolaGeoplanoideaDugesiidaeDugesia

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001007831 – 559POU domain protein 1Add BLAST559

Structurei

3D structure databases

ProteinModelPortaliP31370.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini259 – 333POU-specificPROSITE-ProRule annotationAdd BLAST75

Sequence similaritiesi

Belongs to the POU transcription factor family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
Contains 1 POU-specific domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31370-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQVSHIGSS HFNINSSIKT ALPLINSQYN SLVNESTISS NINLPFRLDA
60 70 80 90 100
PSLFNGLPEE WGPTDAELST HSNVNYPGLT EATIDYKFCS TLNSYFDTNQ
110 120 130 140 150
RFGNVPNDTY LMANSMAANI ENNSWHNSRY YFDGNHPLSQ WLPVPVNCWS
160 170 180 190 200
NNNYIRDDFY DKSIQEEEFK SRSVLQTNEK NSTNVSSDIN HYKPLITDEN
210 220 230 240 250
ENLKMTKPTH NLLNNDSINL CRFPQNEIIM PDLINAPSPT LTNNNLFYSC
260 270 280 290 300
GDHRSGKTED LPSSDDLEQF AKMFKQRRIK LGYTQADVGL ALGTLYGNVF
310 320 330 340 350
SQTTICRFEA LQLSFKNMCK LRPLLQKWLH EADSSSESPT NFDKISAQSR
360 370 380 390 400
KRKKRTSIEA NVKSILESSF MKLSKPSAQD ISSLAEKLSL EKEVVRVWFC
410 420 430 440 450
NRRQKEKRIT PSFDVNEQFD NEVSSTMPYS TLNDDRNEKT IKNSFENHEK
460 470 480 490 500
LIKQTGETNH EQNNNSSVKR LKIRKEPDQI SINDENTSCR AESSGIVPDT
510 520 530 540 550
HYRQECDNHS ICGYNIHDIH ESSVLMSDPV SFYPRSFFMK NNIYSNGTTP

TLFDHSQMI
Length:559
Mass (Da):63,999
Last modified:July 1, 1993 - v1
Checksum:iE4161FE2A4CF2230
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12924 mRNA. Translation: BAA02308.1.
PIRiJQ2010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12924 mRNA. Translation: BAA02308.1.
PIRiJQ2010.

3D structure databases

ProteinModelPortaliP31370.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPOU1_DUGJA
AccessioniPrimary (citable) accession number: P31370
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: October 5, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.