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P31370

- POU1_DUGJA

UniProt

P31370 - POU1_DUGJA

Protein

POU domain protein 1

Gene

POU1

Organism
Dugesia japonica (Planarian)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (01 Jul 1993)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi351 – 41060HomeoboxPROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: InterPro

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    POU domain protein 1
    Short name:
    DjPOU1
    Gene namesi
    Name:POU1
    OrganismiDugesia japonica (Planarian)
    Taxonomic identifieri6161 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesRhabditophoraSeriataTricladidaContinenticolaGeoplanoideaDugesiidaeDugesia

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 559559POU domain protein 1PRO_0000100783Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP31370.
    SMRiP31370. Positions 265-411.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini259 – 33375POU-specificPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the POU transcription factor family.Curated
    Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
    Contains 1 POU-specific domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Homeobox

    Family and domain databases

    Gene3Di1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view]
    PRINTSiPR00028. POUDOMAIN.
    SMARTiSM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P31370-1 [UniParc]FASTAAdd to Basket

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    MTQVSHIGSS HFNINSSIKT ALPLINSQYN SLVNESTISS NINLPFRLDA    50
    PSLFNGLPEE WGPTDAELST HSNVNYPGLT EATIDYKFCS TLNSYFDTNQ 100
    RFGNVPNDTY LMANSMAANI ENNSWHNSRY YFDGNHPLSQ WLPVPVNCWS 150
    NNNYIRDDFY DKSIQEEEFK SRSVLQTNEK NSTNVSSDIN HYKPLITDEN 200
    ENLKMTKPTH NLLNNDSINL CRFPQNEIIM PDLINAPSPT LTNNNLFYSC 250
    GDHRSGKTED LPSSDDLEQF AKMFKQRRIK LGYTQADVGL ALGTLYGNVF 300
    SQTTICRFEA LQLSFKNMCK LRPLLQKWLH EADSSSESPT NFDKISAQSR 350
    KRKKRTSIEA NVKSILESSF MKLSKPSAQD ISSLAEKLSL EKEVVRVWFC 400
    NRRQKEKRIT PSFDVNEQFD NEVSSTMPYS TLNDDRNEKT IKNSFENHEK 450
    LIKQTGETNH EQNNNSSVKR LKIRKEPDQI SINDENTSCR AESSGIVPDT 500
    HYRQECDNHS ICGYNIHDIH ESSVLMSDPV SFYPRSFFMK NNIYSNGTTP 550
    TLFDHSQMI 559
    Length:559
    Mass (Da):63,999
    Last modified:July 1, 1993 - v1
    Checksum:iE4161FE2A4CF2230
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12924 mRNA. Translation: BAA02308.1.
    PIRiJQ2010.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12924 mRNA. Translation: BAA02308.1 .
    PIRi JQ2010.

    3D structure databases

    ProteinModelPortali P31370.
    SMRi P31370. Positions 265-411.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 1.10.10.60. 1 hit.
    1.10.260.40. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR010982. Lambda_DNA-bd_dom.
    IPR013847. POU.
    IPR000327. POU_specific.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00157. Pou. 1 hit.
    [Graphical view ]
    PRINTSi PR00028. POUDOMAIN.
    SMARTi SM00389. HOX. 1 hit.
    SM00352. POU. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 1 hit.
    SSF47413. SSF47413. 1 hit.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00035. POU_1. 1 hit.
    PS00465. POU_2. 1 hit.
    PS51179. POU_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "POU-domain genes in planarian Dugesia japonica: the structure and expression."
      Orii H., Agata K., Watanabe K.
      Biochem. Biophys. Res. Commun. 192:1395-1402(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPOU1_DUGJA
    AccessioniPrimary (citable) accession number: P31370
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1993
    Last sequence update: July 1, 1993
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3