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P31370

- POU1_DUGJA

UniProt

P31370 - POU1_DUGJA

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Protein

POU domain protein 1

Gene

POU1

Organism
Dugesia japonica (Planarian)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi351 – 41060HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain protein 1
Short name:
DjPOU1
Gene namesi
Name:POU1
OrganismiDugesia japonica (Planarian)
Taxonomic identifieri6161 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesRhabditophoraSeriataTricladidaContinenticolaGeoplanoideaDugesiidaeDugesia

Subcellular locationi

Nucleus Curated

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 559559POU domain protein 1PRO_0000100783Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP31370.
SMRiP31370. Positions 265-411.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini259 – 33375POU-specificPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation
Contains 1 POU-specific domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31370-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTQVSHIGSS HFNINSSIKT ALPLINSQYN SLVNESTISS NINLPFRLDA
60 70 80 90 100
PSLFNGLPEE WGPTDAELST HSNVNYPGLT EATIDYKFCS TLNSYFDTNQ
110 120 130 140 150
RFGNVPNDTY LMANSMAANI ENNSWHNSRY YFDGNHPLSQ WLPVPVNCWS
160 170 180 190 200
NNNYIRDDFY DKSIQEEEFK SRSVLQTNEK NSTNVSSDIN HYKPLITDEN
210 220 230 240 250
ENLKMTKPTH NLLNNDSINL CRFPQNEIIM PDLINAPSPT LTNNNLFYSC
260 270 280 290 300
GDHRSGKTED LPSSDDLEQF AKMFKQRRIK LGYTQADVGL ALGTLYGNVF
310 320 330 340 350
SQTTICRFEA LQLSFKNMCK LRPLLQKWLH EADSSSESPT NFDKISAQSR
360 370 380 390 400
KRKKRTSIEA NVKSILESSF MKLSKPSAQD ISSLAEKLSL EKEVVRVWFC
410 420 430 440 450
NRRQKEKRIT PSFDVNEQFD NEVSSTMPYS TLNDDRNEKT IKNSFENHEK
460 470 480 490 500
LIKQTGETNH EQNNNSSVKR LKIRKEPDQI SINDENTSCR AESSGIVPDT
510 520 530 540 550
HYRQECDNHS ICGYNIHDIH ESSVLMSDPV SFYPRSFFMK NNIYSNGTTP

TLFDHSQMI
Length:559
Mass (Da):63,999
Last modified:July 1, 1993 - v1
Checksum:iE4161FE2A4CF2230
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D12924 mRNA. Translation: BAA02308.1.
PIRiJQ2010.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D12924 mRNA. Translation: BAA02308.1 .
PIRi JQ2010.

3D structure databases

ProteinModelPortali P31370.
SMRi P31370. Positions 265-411.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view ]
PRINTSi PR00028. POUDOMAIN.
SMARTi SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "POU-domain genes in planarian Dugesia japonica: the structure and expression."
    Orii H., Agata K., Watanabe K.
    Biochem. Biophys. Res. Commun. 192:1395-1402(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiPOU1_DUGJA
AccessioniPrimary (citable) accession number: P31370
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3