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P31370 (POU1_DUGJA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
POU domain protein 1

Short name=DjPOU1
Gene names
Name:POU1
OrganismDugesia japonica (Planarian)
Taxonomic identifier6161 [NCBI]
Taxonomic lineageEukaryotaMetazoaPlatyhelminthesRhabditophoraSeriataTricladidaContinenticolaGeoplanoideaDugesiidaeDugesia

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus Probable.

Sequence similarities

Belongs to the POU transcription factor family.

Contains 1 homeobox DNA-binding domain.

Contains 1 POU-specific domain.

Ontologies

Keywords
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559POU domain protein 1
PRO_0000100783

Regions

Domain259 – 33375POU-specific
DNA binding351 – 41060Homeobox

Sequences

Sequence LengthMass (Da)Tools
P31370 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: E4161FE2A4CF2230

FASTA55963,999
        10         20         30         40         50         60 
MTQVSHIGSS HFNINSSIKT ALPLINSQYN SLVNESTISS NINLPFRLDA PSLFNGLPEE 

        70         80         90        100        110        120 
WGPTDAELST HSNVNYPGLT EATIDYKFCS TLNSYFDTNQ RFGNVPNDTY LMANSMAANI 

       130        140        150        160        170        180 
ENNSWHNSRY YFDGNHPLSQ WLPVPVNCWS NNNYIRDDFY DKSIQEEEFK SRSVLQTNEK 

       190        200        210        220        230        240 
NSTNVSSDIN HYKPLITDEN ENLKMTKPTH NLLNNDSINL CRFPQNEIIM PDLINAPSPT 

       250        260        270        280        290        300 
LTNNNLFYSC GDHRSGKTED LPSSDDLEQF AKMFKQRRIK LGYTQADVGL ALGTLYGNVF 

       310        320        330        340        350        360 
SQTTICRFEA LQLSFKNMCK LRPLLQKWLH EADSSSESPT NFDKISAQSR KRKKRTSIEA 

       370        380        390        400        410        420 
NVKSILESSF MKLSKPSAQD ISSLAEKLSL EKEVVRVWFC NRRQKEKRIT PSFDVNEQFD 

       430        440        450        460        470        480 
NEVSSTMPYS TLNDDRNEKT IKNSFENHEK LIKQTGETNH EQNNNSSVKR LKIRKEPDQI 

       490        500        510        520        530        540 
SINDENTSCR AESSGIVPDT HYRQECDNHS ICGYNIHDIH ESSVLMSDPV SFYPRSFFMK 

       550 
NNIYSNGTTP TLFDHSQMI 

« Hide

References

[1]"POU-domain genes in planarian Dugesia japonica: the structure and expression."
Orii H., Agata K., Watanabe K.
Biochem. Biophys. Res. Commun. 192:1395-1402(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D12924 mRNA. Translation: BAA02308.1.
PIRJQ2010.

3D structure databases

ProteinModelPortalP31370.
SMRP31370. Positions 265-411.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_specific.
[Graphical view]
PfamPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSPR00028. POUDOMAIN.
SMARTSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePOU1_DUGJA
AccessionPrimary (citable) accession number: P31370
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: October 16, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families