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Protein

POU domain protein 1

Gene

POU1

Organism
Dugesia japonica (Planarian)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi351 – 410HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain protein 1
Short name:
DjPOU1
Gene namesi
Name:POU1
OrganismiDugesia japonica (Planarian)
Taxonomic identifieri6161 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesRhabditophoraSeriataTricladidaContinenticolaGeoplanoideaDugesiidaeDugesia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001007831 – 559POU domain protein 1Add BLAST559

Structurei

3D structure databases

ProteinModelPortaliP31370.
SMRiP31370.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini259 – 333POU-specificPROSITE-ProRule annotationAdd BLAST75

Sequence similaritiesi

Belongs to the POU transcription factor family.Curated

Keywords - Domaini

Homeobox

Family and domain databases

CDDicd00086. homeodomain. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

P31370-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQVSHIGSS HFNINSSIKT ALPLINSQYN SLVNESTISS NINLPFRLDA
60 70 80 90 100
PSLFNGLPEE WGPTDAELST HSNVNYPGLT EATIDYKFCS TLNSYFDTNQ
110 120 130 140 150
RFGNVPNDTY LMANSMAANI ENNSWHNSRY YFDGNHPLSQ WLPVPVNCWS
160 170 180 190 200
NNNYIRDDFY DKSIQEEEFK SRSVLQTNEK NSTNVSSDIN HYKPLITDEN
210 220 230 240 250
ENLKMTKPTH NLLNNDSINL CRFPQNEIIM PDLINAPSPT LTNNNLFYSC
260 270 280 290 300
GDHRSGKTED LPSSDDLEQF AKMFKQRRIK LGYTQADVGL ALGTLYGNVF
310 320 330 340 350
SQTTICRFEA LQLSFKNMCK LRPLLQKWLH EADSSSESPT NFDKISAQSR
360 370 380 390 400
KRKKRTSIEA NVKSILESSF MKLSKPSAQD ISSLAEKLSL EKEVVRVWFC
410 420 430 440 450
NRRQKEKRIT PSFDVNEQFD NEVSSTMPYS TLNDDRNEKT IKNSFENHEK
460 470 480 490 500
LIKQTGETNH EQNNNSSVKR LKIRKEPDQI SINDENTSCR AESSGIVPDT
510 520 530 540 550
HYRQECDNHS ICGYNIHDIH ESSVLMSDPV SFYPRSFFMK NNIYSNGTTP

TLFDHSQMI
Length:559
Mass (Da):63,999
Last modified:July 1, 1993 - v1
Checksum:iE4161FE2A4CF2230
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12924 mRNA. Translation: BAA02308.1.
PIRiJQ2010.

Similar proteinsi

Entry informationi

Entry nameiPOU1_DUGJA
AccessioniPrimary (citable) accession number: P31370
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: September 27, 2017
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families