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Protein

54S ribosomal protein L9, mitochondrial

Gene

MRPL9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

Miscellaneous

Present with 3200 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30901-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L9, mitochondrial
Alternative name(s):
Mitochondrial large ribosomal subunit protein uL3m1 Publication
YmL9
Gene namesi
Name:MRPL9
Ordered Locus Names:YGR220C
ORF Names:G8520
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR220C
SGDiS000003452 MRPL9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 19Mitochondrion2 PublicationsAdd BLAST19
ChainiPRO_000003053620 – 26954S ribosomal protein L9, mitochondrialAdd BLAST250

Proteomic databases

MaxQBiP31334
PaxDbiP31334
PRIDEiP31334

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.2 Publications

Protein-protein interaction databases

BioGridi33473, 136 interactors
ComplexPortaliCPX-1602 54S mitochondrial large ribosomal subunit
DIPiDIP-6806N
IntActiP31334, 46 interactors
MINTiP31334
STRINGi4932.YGR220C

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20C1-269[»]
5MRCelectron microscopy3.25C21-269[»]
5MREelectron microscopy3.75C21-269[»]
5MRFelectron microscopy4.97C21-269[»]
ProteinModelPortaliP31334
SMRiP31334
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

GeneTreeiENSGT00390000011422
HOGENOMiHOG000100368
InParanoidiP31334
KOiK02906
OMAiKGMRMAG
OrthoDBiEOG092C45IZ

Family and domain databases

HAMAPiMF_01325_B Ribosomal_L3_B, 1 hit
InterProiView protein in InterPro
IPR000597 Ribosomal_L3
IPR019927 Ribosomal_L3_bac/org-type
IPR019926 Ribosomal_L3_CS
IPR009000 Transl_B-barrel_sf
PANTHERiPTHR11229 PTHR11229, 1 hit
PfamiView protein in Pfam
PF00297 Ribosomal_L3, 1 hit
SUPFAMiSSF50447 SSF50447, 1 hit
TIGRFAMsiTIGR03625 L3_bact, 1 hit
PROSITEiView protein in PROSITE
PS00474 RIBOSOMAL_L3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P31334-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKFLQGSIF SISKLHVRYS STRPFLVAPS IANSITTEAP AINHSPELAN
60 70 80 90 100
ARKWLPKRCG LITRKKGMMP YFDKSTGERS AATILEVNNV EVIMHRTSEV
110 120 130 140 150
NGYFACQVGY GSRHLSKVSR QMLGHFASKV VNPKEHVAEF RVKDEKGLIP
160 170 180 190 200
PGTLLKPSFF KEGQYVDVRS VSKGKGFTGV MKRYGFKGLR ASHGTSIMHR
210 220 230 240 250
HGGSYGQNQD PGRVLPGRKM PGHMGNEHVT IQNVKVLKVD DENNVIWVKG
260
SVAGPKNSFV KIQDAIKKT
Length:269
Mass (Da):29,790
Last modified:October 1, 1996 - v3
Checksum:iA09A4DA5CE9337E5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti21S → V AA sequence (PubMed:3060376).Curated1
Sequence conflicti139E → Q in CAA46148 (PubMed:1597181).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65014 Genomic DNA Translation: CAA46148.1
X87941 Genomic DNA Translation: CAA61168.1
Z73004 Genomic DNA Translation: CAA97248.1
AY558274 Genomic DNA Translation: AAS56600.1
BK006941 Genomic DNA Translation: DAA08313.1
PIRiS23455 R5BYL3
RefSeqiNP_011736.1, NM_001181349.1

Genome annotation databases

EnsemblFungiiYGR220C; YGR220C; YGR220C
GeneIDi853135
KEGGisce:YGR220C

Similar proteinsi

Entry informationi

Entry nameiRM09_YEAST
AccessioniPrimary (citable) accession number: P31334
Secondary accession number(s): D6VV02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 1, 1996
Last modified: June 20, 2018
This is version 154 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

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