P31331 (GLB_NASMU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Globin Alternative name(s): Myoglobin
Organism	Nassarius mutabilis (Sea snail) (Buccinum mutabile)
Taxonomic identifier	31226 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Lophotrochozoa › Mollusca › Gastropoda › Caenogastropoda › Hypsogastropoda › Neogastropoda › Buccinoidea › Nassariidae › Nassarius

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Homodimer.
Miscellaneous	In contrast to the other dimeric myoglobins, N.mutabilis myoglobin is a highly cooperative oxygen binding molecule.
Sequence similarities	Belongs to the globin family.

Ontologies

Keywords
Biological process	Oxygen transport Transport
Ligand	Heme Iron Metal-binding
Molecular function	Muscle protein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: InterPro hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 147	147	Globin		PRO_0000052481
Sites
	Metal binding	66	1	Iron (heme distal ligand) By similarity
	Metal binding	98	1	Iron (heme proximal ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P31331 [UniParc]. Last modified July 1, 1993. Version 1. Checksum: FE2D07817D61CC8C	FASTA	147	15,759
	10 20 30 40 50 60 GLSAEQKTAL KDSWKILAAN GETMVKNSAA MFGLLFEKYP DTKKHFKTFD GDHFAAMKAT 70 80 90 100 110 120 GMGKAHGMSV FSGLGALVSS VDDGECVLGL AKKLSRNHTA RGVTANDFKL MRSIFGEFLD 130 140 KATGGKATES MKSAWDALLG VLIENHQ

References

[1]

"Amino-acid sequence of the cooperative dimeric myoglobin from the radular muscles of the marine gastropod Nassa mutabilis." Parente A., Verde C., Malorni A., Montecucchi P., Aniello F., Geraci G. Biochim. Biophys. Acta 1162:1-9(1993) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE. Tissue: Radular muscle.

Cross-references

Sequence databases
PIR	S29824.
3D structure databases
ProteinModelPortal	P31331.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.490.10. 1 hit.
InterPro	IPR002336. Erythrocruorin. IPR000971. Globin. IPR009050. Globin-like. IPR012292. Globin_dom. [Graphical view]
Pfam	PF00042. Globin. 1 hit. [Graphical view]
PRINTS	PR00611. ERYTHCRUORIN.
SUPFAM	SSF46458. Globin_like. 1 hit.
PROSITE	PS01033. GLOBIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLB_NASMU

Accession

Primary (citable) accession number: P31331

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
Last sequence update:	July 1, 1993
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)