Reviewed,
UniProtKB/Swiss-Prot P31261 (HXA2_NOTVI)
Last modified
November 24, 2009.
Version 54.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Homeobox protein Hox-A2 Alternative name(s): NvHbox-2.8 |
| Organism | Notophthalmus viridescens (Eastern newt) (Triturus viridescens) |
| Taxonomic identifier | 8316 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Caudata › Salamandroidea › Salamandridae › Notophthalmus |
Protein attributes
| Sequence length | 90 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
| Subcellular location | |
| Sequence similarities | Belongs to the Antp homeobox family. Contains 1 homeobox DNA-binding domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Transcription Transcription regulation |
| Cellular component | Nucleus |
| Domain | Homeobox |
| Ligand | DNA-binding |
| Molecular function | Developmental protein |
| Gene Ontology (GO) | |
| Biological process | multicellular organismal development Inferred from electronic annotation. Source: UniProtKB-KW regulation of transcription, DNA-dependentInferred from electronic annotation. Source: InterPro transcriptionInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro transcription factor activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "Homeobox-containing genes in the newt are organized in clusters similar to other vertebrates." Belleville S., Beauchemin M., Tremblay M., Noiseux N., Savard P. Gene 114:179-186(1992) [PubMed: 1351019] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| M84002 Genomic DNA. Translation: AAA49396.1. | |
| PIR | JC1163. |
3D structure databases | |
| SMR | P31261. Positions 4-60. |
| ModBase | Search... |
Phylogenomic databases | |
| HOVERGEN | P31261. |
Family and domain databases | |
| InterPro | IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_region. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view] |
| Gene3D | G3DSA:1.10.10.60. Homeodomain-rel. 1 hit. |
| Pfam | PF00046. Homeobox. 1 hit. [Graphical view] |
| PRINTS | PR00024. HOMEOBOX. |
| SMART | SM00389. HOX. 1 hit. [Graphical view] |
| PROSITE | PS00032. ANTENNAPEDIA. Partial match. PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HXA2_NOTVI | ||||||||
| Accession | Primary (citable) accession number: P31261 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Vertebrate homeotic Hox proteins Nomenclature of vertebrate homeotic Hox proteins and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


