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P31111 (ZIP1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Synaptonemal complex protein ZIP1
Gene names
Name:ZIP1
Ordered Locus Names:YDR285W
ORF Names:D9819.9
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length875 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.

Subcellular location

Nucleus. Chromosome. Note: Synapsed meiotic chromosomes.

Miscellaneous

Present with 391 molecules/cell in log phase SD medium.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

CST9Q060323EBI-29645,EBI-30044

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 875875Synaptonemal complex protein ZIP1
PRO_0000066584

Regions

Coiled coil177 – 333157 Potential
Coiled coil397 – 43842 Potential
Coiled coil456 – 752297 Potential

Amino acid modifications

Modified residue4811Phosphoserine Ref.5

Experimental info

Sequence conflict551T → A in AAA35239. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P31111 [UniParc].

Last modified October 1, 1996. Version 2.
Checksum: 674F12625CD9DDFD

FASTA875100,035
        10         20         30         40         50         60 
MSNFFRDSSM GFKPRPNIFA KLRVRDVDSD SSANTVVENS SNCLDVGSSI EGDDTFKKPH 

        70         80         90        100        110        120 
KTSTEQELIT SMSLSQRNHG YSDDMEIGSP KKTTSTDQYN RILKNDVAAI ENDTDEDFEI 

       130        140        150        160        170        180 
TEVREVSEGV AKETKESHGD PNDSETTLKD SKMHEYTMTN GKAPLHTSIN NSSTSSNDVL 

       190        200        210        220        230        240 
LEAFTNTQRI CSNLKQELQK QQQDNAKLKV RLQSYASNSD KINEKVGKYK SCLETLQERI 

       250        260        270        280        290        300 
ATLTSHKNNQ ETKLKDLRQN HQLYQRRISG FKTSIENLNK TINDLGKNKK EADAELMKKG 

       310        320        330        340        350        360 
KEIEYLKREL DDCSGQLSEE KIKNSSLIQE MGKNREEMIK SIENFFSEDK AHHLLQFNKF 

       370        380        390        400        410        420 
EERVHDLFEK KLQKHFDVAK DTLNVGLRNT TVELSSNTET MLKQQYEDIK ENLEQKMSSS 

       430        440        450        460        470        480 
KDEMAKTINE LSVTQKGLIM GVQEELLTSS GNIQTALVSE MNNTRQELLD DASQTAKNYA 

       490        500        510        520        530        540 
SLENLVKAYK AEIVQSNEYE ERIKHLESER STLSSQKNQI ISSLGTKEAQ YEDLVKKLEA 

       550        560        570        580        590        600 
KNIEISQISG KEQSLTEKNE NLSNELKKVQ DQLEKLNNLN ITTKSNYENK ISSQNEIVKA 

       610        620        630        640        650        660 
LVSENDTLKQ RIQQLVEIKE NEQKDHTTKL EAFQKNNEQL QKLNVEVVQL KAHELELEEQ 

       670        680        690        700        710        720 
NRHLKNCLEK KETGVEESLS DVKTLKQQVI VLKSEKQDIT AEKLELQDNL ESLEEVTKNL 

       730        740        750        760        770        780 
QQKVQSQKRE LEQKIKELEE IKNHKRNEPS KKGTQNFTKP SDSPKKNATT SNLFPNNSAA 

       790        800        810        820        830        840 
IHSPMKKCPK VDHISKSRIN SSKETSKFND EFDLSSSSND DLELTNPSPI QIKPVRGKIK 

       850        860        870 
KGSNCMKPPI SSRKKLLLVE DEDQSLKISK KRRRK 

« Hide

References

« Hide 'large scale' references
[1]"ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis."
Sym M., Engebrecht J.A., Roeder G.S.
Cell 72:365-378(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: BR1824-3B.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[5]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-481, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L06487 Genomic DNA. Translation: AAA35239.1.
U51031 Genomic DNA. Translation: AAB64474.1.
BK006938 Genomic DNA. Translation: DAA12125.1.
PIRS70115.
RefSeqNP_010571.1. NM_001180593.1.

3D structure databases

ProteinModelPortalP31111.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid32338. 67 interactions.
DIPDIP-1240N.
IntActP31111. 4 interactions.
MINTMINT-439827.
STRING4932.YDR285W.

Proteomic databases

PaxDbP31111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYDR285W; YDR285W; YDR285W.
GeneID851879.
KEGGsce:YDR285W.

Organism-specific databases

CYGDYDR285w.
SGDS000002693. ZIP1.

Phylogenomic databases

eggNOGNOG145618.
KOK12768.
OMAEYSANNS.
OrthoDBEOG7PS1RN.

Enzyme and pathway databases

BioCycYEAST:G3O-29849-MONOMER.

Gene expression databases

GenevestigatorP31111.

Family and domain databases

ProtoNetSearch...

Other

NextBio969844.
PROP31111.

Entry information

Entry nameZIP1_YEAST
AccessionPrimary (citable) accession number: P31111
Secondary accession number(s): D6VSR5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 1, 1996
Last modified: April 16, 2014
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome IV

Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD