SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P31111

- ZIP1_YEAST

UniProt

P31111 - ZIP1_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Synaptonemal complex protein ZIP1
Gene
ZIP1, YDR285W, D9819.9
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Required for meiotic chromosome synapsis and cell cycle progression. May act as a molecular zipper to bring homologous chromosomes in close apposition. ZIP1 may encode the transverse filaments of the synaptonemal complex.

GO - Molecular functioni

  1. SUMO polymer binding Source: SGD
  2. chromatin binding Source: SGD
  3. protein binding Source: IntAct

GO - Biological processi

  1. positive regulation of protein sumoylation Source: SGD
  2. reciprocal meiotic recombination Source: SGD
  3. synapsis Source: SGD
Complete GO annotation...

Keywords - Biological processi

Meiosis

Enzyme and pathway databases

BioCyciYEAST:G3O-29849-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptonemal complex protein ZIP1
Gene namesi
Name:ZIP1
Ordered Locus Names:YDR285W
ORF Names:D9819.9
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome IV

Organism-specific databases

CYGDiYDR285w.
SGDiS000002693. ZIP1.

Subcellular locationi

Nucleus. Chromosome
Note: Synapsed meiotic chromosomes.

GO - Cellular componenti

  1. synaptonemal complex Source: SGD
  2. transverse filament Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 875875Synaptonemal complex protein ZIP1
PRO_0000066584Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei481 – 4811Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP31111.

Expressioni

Gene expression databases

GenevestigatoriP31111.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CST9Q060323EBI-29645,EBI-30044

Protein-protein interaction databases

BioGridi32338. 68 interactions.
DIPiDIP-1240N.
IntActiP31111. 4 interactions.
MINTiMINT-439827.
STRINGi4932.YDR285W.

Structurei

3D structure databases

ProteinModelPortaliP31111.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili177 – 333157 Reviewed prediction
Add
BLAST
Coiled coili397 – 43842 Reviewed prediction
Add
BLAST
Coiled coili456 – 752297 Reviewed prediction
Add
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG145618.
KOiK12768.
OMAiIKHEHER.
OrthoDBiEOG7PS1RN.

Sequencei

Sequence statusi: Complete.

P31111-1 [UniParc]FASTAAdd to Basket

« Hide

MSNFFRDSSM GFKPRPNIFA KLRVRDVDSD SSANTVVENS SNCLDVGSSI    50
EGDDTFKKPH KTSTEQELIT SMSLSQRNHG YSDDMEIGSP KKTTSTDQYN 100
RILKNDVAAI ENDTDEDFEI TEVREVSEGV AKETKESHGD PNDSETTLKD 150
SKMHEYTMTN GKAPLHTSIN NSSTSSNDVL LEAFTNTQRI CSNLKQELQK 200
QQQDNAKLKV RLQSYASNSD KINEKVGKYK SCLETLQERI ATLTSHKNNQ 250
ETKLKDLRQN HQLYQRRISG FKTSIENLNK TINDLGKNKK EADAELMKKG 300
KEIEYLKREL DDCSGQLSEE KIKNSSLIQE MGKNREEMIK SIENFFSEDK 350
AHHLLQFNKF EERVHDLFEK KLQKHFDVAK DTLNVGLRNT TVELSSNTET 400
MLKQQYEDIK ENLEQKMSSS KDEMAKTINE LSVTQKGLIM GVQEELLTSS 450
GNIQTALVSE MNNTRQELLD DASQTAKNYA SLENLVKAYK AEIVQSNEYE 500
ERIKHLESER STLSSQKNQI ISSLGTKEAQ YEDLVKKLEA KNIEISQISG 550
KEQSLTEKNE NLSNELKKVQ DQLEKLNNLN ITTKSNYENK ISSQNEIVKA 600
LVSENDTLKQ RIQQLVEIKE NEQKDHTTKL EAFQKNNEQL QKLNVEVVQL 650
KAHELELEEQ NRHLKNCLEK KETGVEESLS DVKTLKQQVI VLKSEKQDIT 700
AEKLELQDNL ESLEEVTKNL QQKVQSQKRE LEQKIKELEE IKNHKRNEPS 750
KKGTQNFTKP SDSPKKNATT SNLFPNNSAA IHSPMKKCPK VDHISKSRIN 800
SSKETSKFND EFDLSSSSND DLELTNPSPI QIKPVRGKIK KGSNCMKPPI 850
SSRKKLLLVE DEDQSLKISK KRRRK 875
Length:875
Mass (Da):100,035
Last modified:October 1, 1996 - v2
Checksum:i674F12625CD9DDFD
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti55 – 551T → A in AAA35239. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L06487 Genomic DNA. Translation: AAA35239.1.
U51031 Genomic DNA. Translation: AAB64474.1.
BK006938 Genomic DNA. Translation: DAA12125.1.
PIRiS70115.
RefSeqiNP_010571.1. NM_001180593.1.

Genome annotation databases

EnsemblFungiiYDR285W; YDR285W; YDR285W.
GeneIDi851879.
KEGGisce:YDR285W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L06487 Genomic DNA. Translation: AAA35239.1 .
U51031 Genomic DNA. Translation: AAB64474.1 .
BK006938 Genomic DNA. Translation: DAA12125.1 .
PIRi S70115.
RefSeqi NP_010571.1. NM_001180593.1.

3D structure databases

ProteinModelPortali P31111.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 32338. 68 interactions.
DIPi DIP-1240N.
IntActi P31111. 4 interactions.
MINTi MINT-439827.
STRINGi 4932.YDR285W.

Proteomic databases

PaxDbi P31111.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YDR285W ; YDR285W ; YDR285W .
GeneIDi 851879.
KEGGi sce:YDR285W.

Organism-specific databases

CYGDi YDR285w.
SGDi S000002693. ZIP1.

Phylogenomic databases

eggNOGi NOG145618.
KOi K12768.
OMAi IKHEHER.
OrthoDBi EOG7PS1RN.

Enzyme and pathway databases

BioCyci YEAST:G3O-29849-MONOMER.

Miscellaneous databases

NextBioi 969844.
PROi P31111.

Gene expression databases

Genevestigatori P31111.

Family and domain databases

ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis."
    Sym M., Engebrecht J.A., Roeder G.S.
    Cell 72:365-378(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: BR1824-3B.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  5. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-481, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiZIP1_YEAST
AccessioniPrimary (citable) accession number: P31111
Secondary accession number(s): D6VSR5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 1, 1996
Last modified: July 9, 2014
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 391 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3

Similar proteinsi