Reviewed,
UniProtKB/Swiss-Prot P31104 (AROC_BACSU)
Last modified
November 3, 2009.
Version 73.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin
| Protein names | Recommended name: Chorismate synthase EC=4.2.3.5 Alternative name(s): 5-enolpyruvylshikimate-3-phosphate phospholyase Vegetative protein 216 Short name=VEG216 | ||||
| Gene names |
| ||||
| Organism | Bacillus subtilis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1423 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 390 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300 |
| Cofactor | Reduced flavin By similarity. |
| Pathway | Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300 |
| Subunit structure | Homotetramer By similarity. |
| Sequence similarities | Belongs to the chorismate synthase family. |
| Sequence caution | The sequence AAA20859.1 differs from that shown. Reason: Frameshift at position 355. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis |
| Molecular function | Lyase |
| Technical term | Complete proteome Direct protein sequencing |
| Gene Ontology (GO) | |
| Biological process | aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | chorismate synthase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Sequence of Bacillus subtilis dbpA, mtr(A,B), gerC(1-3), ndk, cheR, aro(B,E,F,H), trp(A-F), hisH, and tyrA genes." Henner D.J. Submitted (JAN-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
| [3] | "Detecting and analyzing DNA sequencing errors: toward a higher quality of the Bacillus subtilis genome sequence." Medigue C., Rose M., Viari A., Danchin A. Genome Res. 9:1116-1127(1999) [PubMed: 10568751] [Abstract] Cited for: SEQUENCE REVISION. |
| [4] | "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later." Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A. Microbiology 155:1758-1775(2009) [PubMed: 19383706] [Abstract] Cited for: SEQUENCE REVISION TO 362-363. |
| [5] | "First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis." Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M. Electrophoresis 18:1451-1463(1997) [PubMed: 9298659] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-10. Strain: 168 / IS58. |
Cross-references
Sequence databases | |
|---|---|
| M80245 Genomic DNA. Translation: AAA20859.1. Frameshift. AL009126 Genomic DNA. Translation: CAB14187.3. | |
| PIR | C69590. |
| RefSeq | NP_390152.3. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 939000. |
| GenomeReviews | Gene locus BSU22710 in contig AL009126_GR. |
| KEGG | bsu:BSU22710. |
Organism-specific databases | |
| SubtiList | BG10284. aroF. [Micado] |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P31104. |
| OMA | PPGLGSH. |
Enzyme and pathway databases | |
| BioCyc | BSUB224308:BSU2270-MON. |
| BRENDA | 4.2.3.5. 150. |
Family and domain databases | |
| HAMAP | MF_00300. [Tree] |
| InterPro | IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view] |
| PANTHER | PTHR21085. Chorismate_synth. 1 hit. |
| Pfam | PF01264. Chorismate_synt. 1 hit. [Graphical view] |
| PIRSF | PIRSF001456. Chorismate_synth. 1 hit. |
| ProDom | PD002941. Chorismate_synth. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR00033. aroC. 1 hit. |
| PROSITE | PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AROC_BACSU | ||||||||
| Accession | Primary (citable) accession number: P31104 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


