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P31104 (AROC_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase

EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Vegetative protein 216
Short name=VEG216
Gene names
Name:aroF
Ordered Locus Names:BSU22710
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesBacillaceaeBacillus

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Sequence caution

The sequence AAA20859.1 differs from that shown. Reason: Frameshift at position 355.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390Chorismate synthase HAMAP MF_00300
PRO_0000140553

Experimental info

Sequence conflict1751E → G in AAA20859. Ref.1
Sequence conflict362 – 3632NA → T in AAA20859. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P31104 [UniParc].

Last modified July 28, 2009. Version 3.
Checksum: 9D529ABD63651885

FASTA39042,806
        10         20         30         40         50         60 
MRYLTAGESH GPQLTTIIEG VPAGLYITEE DINFELARRQ KGHGRGRRMQ IEKDQAKIMS 

        70         80         90        100        110        120 
GVRHARTLGS PIALVVENND WKHWTKIMGA APITEDEEKE MKRQISRPRP GHADLNGAIK 

       130        140        150        160        170        180 
YNHRDMRNVL ERSSARETTV RVAAGAVAKK ILSELGIKVA GHVLQIGAVK AEKTEYTSIE 

       190        200        210        220        230        240 
DLQRVTEESP VRCYDEEAGK KMMAAIDEAK ANGDSIGGIV EVIVEGMPVG VGSYVHYDRK 

       250        260        270        280        290        300 
LDSKLAAAVL SINAFKGVEF GIGFEAAGRN GSEVHDEIIW DEEKGYTRAT NRLGGLEGGM 

       310        320        330        340        350        360 
TTGMPIVVRG VMKPIPTLYK PLKSVDIETK EPFSASIERS DSCAVPAASV VAEAAVAWEI 

       370        380        390 
ANAVVEQFGL DQIDRIRENV ENMRKLSREF 

« Hide

References

« Hide 'large scale' references
[1]"Sequence of Bacillus subtilis dbpA, mtr(A,B), gerC(1-3), ndk, cheR, aro(B,E,F,H), trp(A-F), hisH, and tyrA genes."
Henner D.J.
Submitted (JAN-1992) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[3]"Detecting and analyzing DNA sequencing errors: toward a higher quality of the Bacillus subtilis genome sequence."
Medigue C., Rose M., Viari A., Danchin A.
Genome Res. 9:1116-1127(1999) [PubMed: 10568751] [Abstract]
Cited for: SEQUENCE REVISION.
[4]"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
Microbiology 155:1758-1775(2009) [PubMed: 19383706] [Abstract]
Cited for: SEQUENCE REVISION TO 362-363.
[5]"First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis."
Antelmann H., Bernhardt J., Schmid R., Mach H., Voelker U., Hecker M.
Electrophoresis 18:1451-1463(1997) [PubMed: 9298659] [Abstract]
Cited for: PROTEIN SEQUENCE OF 1-10.
Strain: 168 / IS58.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M80245 Genomic DNA. Translation: AAA20859.1. Frameshift.
AL009126 Genomic DNA. Translation: CAB14187.3.
PIRC69590.
RefSeqNP_390152.3. NC_000964.3.

3D structure databases

ProteinModelPortalP31104.
SMRP31104. Positions 1-390.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000001840; EBBACP00000001840; EBBACG00000001837.
GeneID939000.
GenomeReviewsGene locus BSU22710 in contig AL009126_GR.
KEGGbsu:BSU22710.
PATRIC18976351. VBIBacSub10457_2366.

Organism-specific databases

GenoListBSU22710. [Micado]

Phylogenomic databases

GeneTreeEBGT00050000002373.
HOGENOMHBG292336.
PhylomeDBP31104.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycBSUB:BSU22710-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_BACSU
AccessionPrimary (citable) accession number: P31104
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 28, 2009
Last modified: January 25, 2012
This is version 89 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families