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Protein

Photosystem I iron-sulfur center

Gene

psaC

Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE to PSI. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
Mutant proteins with a 3Fe-4S center are not observed bound to PSI in vitro, and are probably not able to do so in vivo.

Catalytic activityi

Reduced plastocyanin + oxidized ferredoxin + light = oxidized plastocyanin + reduced ferredoxin.

Cofactori

[4Fe-4S] clusterNote: Binds 2 [4Fe-4S] clusters. Cluster 2 is most probably the spectroscopically characterized electron acceptor FA and cluster 1 is most probably FB.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi11 – 111Iron-sulfur 1 (4Fe-4S)
Metal bindingi14 – 141Iron-sulfur 1 (4Fe-4S)
Metal bindingi17 – 171Iron-sulfur 1 (4Fe-4S)
Metal bindingi21 – 211Iron-sulfur 2 (4Fe-4S)
Metal bindingi48 – 481Iron-sulfur 2 (4Fe-4S)
Metal bindingi51 – 511Iron-sulfur 2 (4Fe-4S)
Metal bindingi54 – 541Iron-sulfur 2 (4Fe-4S)
Metal bindingi58 – 581Iron-sulfur 1 (4Fe-4S)

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Photosynthesis, Transport

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciSSP32049:GKF7-1590-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Photosystem I iron-sulfur center (EC:1.97.1.12)
Alternative name(s):
9 kDa polypeptide
PSI-C
Photosystem I subunit VII
PsaC
Gene namesi
Name:psaC
Ordered Locus Names:SYNPCC7002_A1589
OrganismiSynechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (Agmenellum quadruplicatum)
Taxonomic identifieri32049 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechococcus
Proteomesi
  • UP000001688 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Photosystem I, Thylakoid

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi14 – 141C → A, D or S: Generates altered FB cluster (in vitro). 2 Publications
Mutagenesisi21 – 211C → D: Unable to bind PSI cores (in vitro). 1 Publication
Mutagenesisi34 – 341C → A or S: No measurable effect. 1 Publication
Mutagenesisi51 – 511C → A, D or S: Generates altered FA cluster (in vitro). 3 Publications
Mutagenesisi58 – 581C → D: Unable to bind PSI cores (in vitro). 1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 8180Photosystem I iron-sulfur centerPRO_0000062021Add
BLAST

Interactioni

Subunit structurei

The cyanobacterial PSI reaction center is composed of one copy each of PsaA,B,C,D,E,F,I,J,K,L,M and X, and forms trimeric complexes.By similarity

Protein-protein interaction databases

STRINGi32049.SYNPCC7002_A1589.

Structurei

Secondary structure

1
81
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi18 – 203Combined sources
Beta strandi26 – 305Combined sources
Beta strandi32 – 343Combined sources
Beta strandi37 – 415Combined sources
Beta strandi60 – 634Combined sources
Turni69 – 713Combined sources
Beta strandi74 – 796Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K0TNMR-A2-81[»]
ProteinModelPortaliP31087.
SMRiP31087. Positions 2-81.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP31087.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 31304Fe-4S ferredoxin-type 1Add
BLAST
Domaini37 – 68324Fe-4S ferredoxin-type 2Add
BLAST

Sequence similaritiesi

Contains 2 4Fe-4S ferredoxin-type domains.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108Z6M. Bacteria.
COG1145. LUCA.
HOGENOMiHOG000230505.
KOiK02691.
OMAiGQIAASP.
OrthoDBiPOG091H01RQ.

Family and domain databases

HAMAPiMF_01303. PSI_PsaC. 1 hit.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017491. PSI_PsaC.
[Graphical view]
PfamiPF12838. Fer4_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03048. PS_I_psaC. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P31087-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHSVKIYDT CIGCTQCVRA CPLDVLEMVP WDGCKAGQIA SSPRTEDCVG
60 70 80
CKRCETACPT DFLSIRVYLG AETTRSMGLA Y
Length:81
Mass (Da):8,814
Last modified:January 23, 2007 - v2
Checksum:i57B7D4A3371A4AFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86238 Genomic DNA. Translation: AAA27353.1.
CP000951 Genomic DNA. Translation: ACA99580.1.

Genome annotation databases

EnsemblBacteriaiACA99580; ACA99580; SYNPCC7002_A1589.
KEGGisyp:SYNPCC7002_A1589.
PATRICi23817792. VBISynSp37135_1840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M86238 Genomic DNA. Translation: AAA27353.1.
CP000951 Genomic DNA. Translation: ACA99580.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1K0TNMR-A2-81[»]
ProteinModelPortaliP31087.
SMRiP31087. Positions 2-81.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi32049.SYNPCC7002_A1589.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACA99580; ACA99580; SYNPCC7002_A1589.
KEGGisyp:SYNPCC7002_A1589.
PATRICi23817792. VBISynSp37135_1840.

Phylogenomic databases

eggNOGiENOG4108Z6M. Bacteria.
COG1145. LUCA.
HOGENOMiHOG000230505.
KOiK02691.
OMAiGQIAASP.
OrthoDBiPOG091H01RQ.

Enzyme and pathway databases

BioCyciSSP32049:GKF7-1590-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP31087.

Family and domain databases

HAMAPiMF_01303. PSI_PsaC. 1 hit.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR017491. PSI_PsaC.
[Graphical view]
PfamiPF12838. Fer4_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03048. PS_I_psaC. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 2 hits.
PS51379. 4FE4S_FER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPSAC_SYNP2
AccessioniPrimary (citable) accession number: P31087
Secondary accession number(s): B1XNQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 117 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.