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Protein

Flagellar assembly protein FliH

Gene

fliH

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Needed for flagellar regrowth and assembly.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:EG11656-MONOMER.
ECOL316407:JW1924-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar assembly protein FliH
Gene namesi
Name:fliH
Synonyms:fla AII.3, fla BIII
Ordered Locus Names:b1940, JW1924
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11656. fliH.

Subcellular locationi

GO - Cellular componenti

  • bacterial-type flagellum Source: InterPro
  • cytosol Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 228228Flagellar assembly protein FliHPRO_0000180893Add
BLAST

Proteomic databases

PaxDbiP31068.

Interactioni

Protein-protein interaction databases

BioGridi4260385. 15 interactions.
DIPiDIP-9654N.
IntActiP31068. 12 interactions.
STRINGi511145.b1940.

Structurei

3D structure databases

ProteinModelPortaliP31068.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FliH family.Curated

Phylogenomic databases

eggNOGiENOG41090PJ. Bacteria.
COG1317. LUCA.
HOGENOMiHOG000265861.
InParanoidiP31068.
KOiK02411.
OMAiPGGCKIS.
OrthoDBiEOG6FNHNK.

Family and domain databases

InterProiIPR000563. Flag_FliH.
IPR018035. Flagellar_FliH/T3SS_HrpE.
[Graphical view]
PfamiPF02108. FliH. 1 hit.
[Graphical view]
PRINTSiPR01003. FLGFLIH.

Sequencei

Sequence statusi: Complete.

P31068-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDNLPWKTW TPDDLAPPQA EFVPIVEPEE TIIEEAEPSL EQQLAQLQMQ
60 70 80 90 100
AHEQGYQAGI AEGRQQGHKQ GYQEGLAQGL EQGLAEAKSQ QAPIHARMQQ
110 120 130 140 150
LVSEFQTTLD ALDSVIASRL MQMALEAARQ VIGQTPTVDN SALIKQIQQL
160 170 180 190 200
LQQEPLFSGK PQLRVHPDDL QRVDDMLGAT LSLHGWRLRG DPTLHPGGCK
210 220
VSADEGDLDA SVATRWQELC RLAAPGVV
Length:228
Mass (Da):25,050
Last modified:November 1, 1997 - v3
Checksum:iDF49BC3C0456552A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti3 – 31D → N in L13243 (PubMed:8224881).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75007.2.
AP009048 Genomic DNA. Translation: BAA15765.1.
L13243 Genomic DNA. No translation available.
L49147 Genomic DNA. Translation: AAA82636.1.
PIRiA64958.
RefSeqiNP_416450.2. NC_000913.3.
WP_001282683.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75007; AAC75007; b1940.
BAA15765; BAA15765; BAA15765.
GeneIDi946456.
KEGGiecj:JW1924.
eco:b1940.
PATRICi32119209. VBIEscCol129921_2019.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75007.2.
AP009048 Genomic DNA. Translation: BAA15765.1.
L13243 Genomic DNA. No translation available.
L49147 Genomic DNA. Translation: AAA82636.1.
PIRiA64958.
RefSeqiNP_416450.2. NC_000913.3.
WP_001282683.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP31068.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260385. 15 interactions.
DIPiDIP-9654N.
IntActiP31068. 12 interactions.
STRINGi511145.b1940.

Proteomic databases

PaxDbiP31068.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75007; AAC75007; b1940.
BAA15765; BAA15765; BAA15765.
GeneIDi946456.
KEGGiecj:JW1924.
eco:b1940.
PATRICi32119209. VBIEscCol129921_2019.

Organism-specific databases

EchoBASEiEB1608.
EcoGeneiEG11656. fliH.

Phylogenomic databases

eggNOGiENOG41090PJ. Bacteria.
COG1317. LUCA.
HOGENOMiHOG000265861.
InParanoidiP31068.
KOiK02411.
OMAiPGGCKIS.
OrthoDBiEOG6FNHNK.

Enzyme and pathway databases

BioCyciEcoCyc:EG11656-MONOMER.
ECOL316407:JW1924-MONOMER.

Miscellaneous databases

PROiP31068.

Family and domain databases

InterProiIPR000563. Flag_FliH.
IPR018035. Flagellar_FliH/T3SS_HrpE.
[Graphical view]
PfamiPF02108. FliH. 1 hit.
[Graphical view]
PRINTSiPR01003. FLGFLIH.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Gene sequence, overproduction, purification and determination of the wild-type level of the Escherichia coli flagellar switch protein FliG."
    Roman S.J., Frantz B.B., Matsumura P.
    Gene 133:103-108(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-14.
  5. Macnab R.M.
    Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 197-228.
    Strain: K12.

Entry informationi

Entry nameiFLIH_ECOLI
AccessioniPrimary (citable) accession number: P31068
Secondary accession number(s): P76325
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: January 20, 2016
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.