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Protein

UPF0394 inner membrane protein YedE

Gene

yedE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11660-MONOMER.
ECOL316407:JW1914-MONOMER.

Protein family/group databases

TCDBi9.B.102.1.1. the yede/yeee (yede/yeee) family.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0394 inner membrane protein YedE
Gene namesi
Name:yedE
Ordered Locus Names:b1929, JW1914
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11660. yedE.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1313CytoplasmicSequence analysisAdd
BLAST
Transmembranei14 – 3421HelicalSequence analysisAdd
BLAST
Topological domaini35 – 7844PeriplasmicSequence analysisAdd
BLAST
Transmembranei79 – 9921HelicalSequence analysisAdd
BLAST
Topological domaini100 – 11112CytoplasmicSequence analysisAdd
BLAST
Transmembranei112 – 13221HelicalSequence analysisAdd
BLAST
Topological domaini133 – 1331PeriplasmicSequence analysis
Transmembranei134 – 15421HelicalSequence analysisAdd
BLAST
Topological domaini155 – 19844CytoplasmicSequence analysisAdd
BLAST
Transmembranei199 – 21921HelicalSequence analysisAdd
BLAST
Topological domaini220 – 25940PeriplasmicSequence analysisAdd
BLAST
Transmembranei260 – 28021HelicalSequence analysisAdd
BLAST
Topological domaini281 – 2833CytoplasmicSequence analysis
Transmembranei284 – 30421HelicalSequence analysisAdd
BLAST
Topological domaini305 – 36359PeriplasmicSequence analysisAdd
BLAST
Transmembranei364 – 38421HelicalSequence analysisAdd
BLAST
Topological domaini385 – 40117CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401UPF0394 inner membrane protein YedEPRO_0000169090Add
BLAST

Proteomic databases

PaxDbiP31064.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
aroEP157701EBI-544094,EBI-544087

Protein-protein interaction databases

BioGridi4261058. 169 interactions.
DIPiDIP-11839N.
IntActiP31064. 1 interaction.
MINTiMINT-1246874.
STRINGi511145.b1929.

Structurei

3D structure databases

ProteinModelPortaliP31064.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0394 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG41066VF. Bacteria.
COG2391. LUCA.
HOGENOMiHOG000285397.
InParanoidiP31064.
KOiK07112.
OMAiVMIIGMF.
OrthoDBiEOG6QZMVF.

Family and domain databases

InterProiIPR007272. Sulf_transp.
[Graphical view]
PfamiPF04143. Sulf_transp. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P31064-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWQQFKHAW LIKFWAPIPA VIAAGILSTY YFGITGTFWA VTGEFTRWGG
60 70 80 90 100
QLLQLFGVHA EEWGYFKIIH LEGSPLTRID GMMILGMFGG CFAAALWANN
110 120 130 140 150
VKLRMPRSRI RIMQAIIGGI IAGFGARLAM GCNLAAFFTG IPQFSLHAWF
160 170 180 190 200
FAIATAIGSW FGARFTLLPI FRIPVKMQKV SAASPLTQKP DQARRRFRLG
210 220 230 240 250
MLVFFGMLGW ALLTAMNQPK LGLAMLFGVG FGLLIERAQI CFTSAFRDMW
260 270 280 290 300
ITGRTHMAKA IIIGMAVSAI GIFSYVQLGV EPKIMWAGPN AVIGGLLFGF
310 320 330 340 350
GIVLAGGCET GWMYRAVEGQ VHYWWVGLGN VIGSTILAYY WDDFAPALAT
360 370 380 390 400
DWDKINLLKT FGPMGGLLVT YLLLFAALML IIGWEKRFFR RAAPQTAKEI

A
Length:401
Mass (Da):44,429
Last modified:July 1, 1993 - v1
Checksum:iE07554C206B367E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13279 Genomic DNA. Translation: AAA82577.1.
U00096 Genomic DNA. Translation: AAC74996.1.
AP009048 Genomic DNA. Translation: BAA15757.1.
PIRiF64956.
RefSeqiNP_416439.1. NC_000913.3.
WP_000118897.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74996; AAC74996; b1929.
BAA15757; BAA15757; BAA15757.
GeneIDi945192.
KEGGiecj:JW1914.
eco:b1929.
PATRICi32119193. VBIEscCol129921_2011.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L13279 Genomic DNA. Translation: AAA82577.1.
U00096 Genomic DNA. Translation: AAC74996.1.
AP009048 Genomic DNA. Translation: BAA15757.1.
PIRiF64956.
RefSeqiNP_416439.1. NC_000913.3.
WP_000118897.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP31064.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261058. 169 interactions.
DIPiDIP-11839N.
IntActiP31064. 1 interaction.
MINTiMINT-1246874.
STRINGi511145.b1929.

Protein family/group databases

TCDBi9.B.102.1.1. the yede/yeee (yede/yeee) family.

Proteomic databases

PaxDbiP31064.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC74996; AAC74996; b1929.
BAA15757; BAA15757; BAA15757.
GeneIDi945192.
KEGGiecj:JW1914.
eco:b1929.
PATRICi32119193. VBIEscCol129921_2011.

Organism-specific databases

EchoBASEiEB1612.
EcoGeneiEG11660. yedE.

Phylogenomic databases

eggNOGiENOG41066VF. Bacteria.
COG2391. LUCA.
HOGENOMiHOG000285397.
InParanoidiP31064.
KOiK07112.
OMAiVMIIGMF.
OrthoDBiEOG6QZMVF.

Enzyme and pathway databases

BioCyciEcoCyc:EG11660-MONOMER.
ECOL316407:JW1914-MONOMER.

Miscellaneous databases

PROiP31064.

Family and domain databases

InterProiIPR007272. Sulf_transp.
[Graphical view]
PfamiPF04143. Sulf_transp. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Organization of the Escherichia coli and Salmonella typhimurium chromosomes between flagellar regions IIIa and IIIb, including a large non-coding region."
    Raha M., Kihara M., Kawagishi I., Macnab R.M.
    J. Gen. Microbiol. 139:1401-1407(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: JA11.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiYEDE_ECOLI
AccessioniPrimary (citable) accession number: P31064
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: January 20, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.