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P31058 (YADC_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized fimbrial-like protein YadC
Gene names
Name:yadC
Ordered Locus Names:b0135, JW0131
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length412 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Ref.6

Subcellular location

Fimbrium Potential.

Induction

Repressed by H-NS. Ref.6

Disruption phenotype

Deletion of the operon under classical laboratory conditions does not result in any major effect on E.coli capacity to form biofilms compared with the wild-type strain. Ref.6

Miscellaneous

The operon is cryptic under classical laboratory conditions, but is functional when constitutively expressed (Ref.6).

Sequence similarities

Belongs to the fimbrial protein family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 412390Uncharacterized fimbrial-like protein YadC
PRO_0000009253

Experimental info

Sequence conflict206 – 2072LN → VT in X65538. Ref.4
Sequence conflict210 – 2112VQ → IK in X65538. Ref.4
Sequence conflict226 – 24520SPGTK…NFTLN → GAGQGINEHSYFIKIDFDLL in X65538. Ref.4
Sequence conflict2511L → N in X65538. Ref.4
Sequence conflict257 – 2626SILTGP → AMLSGT in X65538. Ref.4
Sequence conflict2651N → T in X65538. Ref.4
Sequence conflict2701R → K in X65538. Ref.4
Sequence conflict276 – 2805SGTIK → AEQKR in X65538. Ref.4
Sequence conflict2841S → T in X65538. Ref.4
Sequence conflict2961I → V in X65538. Ref.4
Sequence conflict2991R → T in X65538. Ref.4
Sequence conflict307 – 3082TG → ST in X65538. Ref.4
Sequence conflict313 – 3153QNT → ETG in X65538. Ref.4
Sequence conflict325 – 3262ST → ND in X65538. Ref.4
Sequence conflict3531T → S in X65538. Ref.4
Sequence conflict3581I → K in X65538. Ref.4
Sequence conflict361 – 3633ETE → DPRGK in X65538. Ref.4
Sequence conflict367 – 3682SD → TG in X65538. Ref.4
Sequence conflict373 – 3808NQGNGTSQ → DQDTGITY in X65538. Ref.4
Sequence conflict3891K → Q in X65538. Ref.4
Sequence conflict3931N → T in X65538. Ref.4
Sequence conflict3951A → P in X65538. Ref.4
Sequence conflict3981P → A in X65538. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P31058 [UniParc].

Last modified June 1, 1994. Version 2.
Checksum: 3945450AD85EB5BE

FASTA41244,899
        10         20         30         40         50         60 
MKTIFRYILF LALYSCCNTV SAYTSFIVGN NAGVDNYRGP STAAQMTFNY TSTASNLVFY 

        70         80         90        100        110        120 
KPTQLGPTGV KMYWSYLDTG TGGGILYCNT SGRANPGPIT IENAMVYSGK DYGGHKLFNT 

       130        140        150        160        170        180 
SVPGLYYTML ISRVWSAYDT ITDIQSPGIY IGDPSNQEFF FSVTDSDLQT KGCNKADDYD 

       190        200        210        220        230        240 
KFWAIGGIVH NITVEFYTDT NFDPTLNQQV QLSSSSNYLY SFKAYSPGTK VVDHSNHIYV 

       250        260        270        280        290        300 
NFTLNNVKLT LPTCFTSILT GPSVNGSTVR MGEYSSGTIK NGASPVPFDI SLQNCIRVRN 

       310        320        330        340        350        360 
IETKLVTGKV GTQNTQLLGN TLTGSTAAKG VGVLIEGLAT SKNPLMTLKP NDTNSVYIDY 

       370        380        390        400        410 
ETEDDTSDGV YPNQGNGTSQ PLHFQATLKQ DGNIAIEPGE FKATSTFQVT YP 

« Hide

References

« Hide 'large scale' references
[1]"Systematic sequencing of the Escherichia coli genome: analysis of the 2.4-4.1 min (110,917-193,643 bp) region."
Fujita N., Mori H., Yura T., Ishihama A.
Nucleic Acids Res. 22:1637-1639(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme."
Jones C.E., Brook J.M., Buck D., Abell C., Smith A.G.
J. Bacteriol. 175:2125-2130(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 196-412.
Strain: K12.
[5]"Nucleotide sequence of the Escherichia coli panBCD gene cluster."
Merkel W.K., Nichols B.P.
Submitted (JUN-1993) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 354-412.
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[6]"Escherichia coli K-12 possesses multiple cryptic but functional chaperone-usher fimbriae with distinct surface specificities."
Korea C.G., Badouraly R., Prevost M.C., Ghigo J.M., Beloin C.
Environ. Microbiol. 12:1957-1977(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, INDUCTION, DISRUPTION PHENOTYPE.
Strain: K12 / MG1655 / ATCC 47076.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC73246.1.
AP009048 Genomic DNA. Translation: BAB96712.1.
X65538 Genomic DNA. No translation available.
L17086 Genomic DNA. No translation available.
PIRG64736.
RefSeqNP_414677.1. NC_000913.3.
YP_488438.1. NC_007779.1.

3D structure databases

ProteinModelPortalP31058.
SMRP31058. Positions 247-412.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-11181N.
STRING511145.b0135.

Proteomic databases

PRIDEP31058.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC73246; AAC73246; b0135.
BAB96712; BAB96712; BAB96712.
GeneID12933212.
944837.
KEGGecj:Y75_p0132.
eco:b0135.
PATRIC32115375. VBIEscCol129921_0139.

Organism-specific databases

EchoBASEEB1629.
EcoGeneEG11678. yadC.

Phylogenomic databases

eggNOGNOG305823.
HOGENOMHOG000116867.
OMAIGVMIEG.
OrthoDBEOG66HVBN.

Enzyme and pathway databases

BioCycEcoCyc:EG11678-MONOMER.
ECOL316407:JW0131-MONOMER.

Gene expression databases

GenevestigatorP31058.

Family and domain databases

Gene3D2.60.40.1090. 1 hit.
InterProIPR008966. Adhesion_dom.
IPR000259. Adhesion_dom_fimbrial.
IPR017014. Fimbrial-like_YadC.
[Graphical view]
PfamPF00419. Fimbrial. 1 hit.
[Graphical view]
PIRSFPIRSF033053. UCP033503_fimbr. 1 hit.
SUPFAMSSF49401. SSF49401. 1 hit.
ProtoNetSearch...

Other

PROP31058.

Entry information

Entry nameYADC_ECOLI
AccessionPrimary (citable) accession number: P31058
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: June 1, 1994
Last modified: June 11, 2014
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene