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Protein

Uncharacterized HTH-type transcriptional regulator YbeF

Gene

ybeF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi46 – 65H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:EG11594-MONOMER.
ECOL316407:JW0624-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YbeF
Gene namesi
Name:ybeF
Ordered Locus Names:b0629, JW0624
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11594. ybeF.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001057791 – 317Uncharacterized HTH-type transcriptional regulator YbeFAdd BLAST317

Proteomic databases

PaxDbiP30979.
PRIDEiP30979.

Interactioni

Protein-protein interaction databases

BioGridi4260778. 8 interactors.
IntActiP30979. 2 interactors.
STRINGi511145.b0629.

Structurei

3D structure databases

ProteinModelPortaliP30979.
SMRiP30979.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 86HTH lysR-typePROSITE-ProRule annotationAdd BLAST58

Sequence similaritiesi

Contains 1 HTH lysR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41064T2. Bacteria.
ENOG4110BBF. LUCA.
HOGENOMiHOG000267879.
OMAiRMTWNES.
PhylomeDBiP30979.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P30979-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSNNQIEPC LSRKSSEGKP QIFTTLRNID LNLLTIFEAV YVHKGIVNAA
60 70 80 90 100
KVLNLTPSAI SQSIQKLRVI FPDPLFIRKG QGVTPTAFAM HLHEYISQGL
110 120 130 140 150
ESILGALDIE GSYDKQRTIT IATTPSVGAL VLPVIYRAIK THYPQLLLRN
160 170 180 190 200
PPISDAENQL SQFQTDLIID NMFCTNRTVQ HHVLFTDNMV LICREGNPLL
210 220 230 240 250
SLEDDRETID NAAHVLLLPE EQNFSGLRQR VQEMFPDRQI NFTSYNILTI
260 270 280 290 300
AALVANSDML AIIPSRFYNL FSRCWPLEKL PFPSLNEEQI DFSIHYNKFS
310
LRDPILHGVI DVIRNAF
Length:317
Mass (Da):35,960
Last modified:November 1, 1997 - v3
Checksum:i27DAC6963541736F
GO

Sequence cautioni

The sequence AAA66344 differs from that shown. Reason: Frameshift at positions 53 and 99.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti297Missing in AAA66344 (PubMed:8444795).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L07636 Genomic DNA. Translation: AAA66344.1. Frameshift.
U82598 Genomic DNA. Translation: AAB40829.1.
U00096 Genomic DNA. Translation: AAC73730.2.
AP009048 Genomic DNA. Translation: BAA35272.1.
PIRiC64797.
RefSeqiNP_415162.4. NC_000913.3.
WP_000378026.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73730; AAC73730; b0629.
BAA35272; BAA35272; BAA35272.
GeneIDi945219.
KEGGiecj:JW0624.
eco:b0629.
PATRICi32116439. VBIEscCol129921_0659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L07636 Genomic DNA. Translation: AAA66344.1. Frameshift.
U82598 Genomic DNA. Translation: AAB40829.1.
U00096 Genomic DNA. Translation: AAC73730.2.
AP009048 Genomic DNA. Translation: BAA35272.1.
PIRiC64797.
RefSeqiNP_415162.4. NC_000913.3.
WP_000378026.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP30979.
SMRiP30979.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260778. 8 interactors.
IntActiP30979. 2 interactors.
STRINGi511145.b0629.

Proteomic databases

PaxDbiP30979.
PRIDEiP30979.

Protocols and materials databases

DNASUi945219.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73730; AAC73730; b0629.
BAA35272; BAA35272; BAA35272.
GeneIDi945219.
KEGGiecj:JW0624.
eco:b0629.
PATRICi32116439. VBIEscCol129921_0659.

Organism-specific databases

EchoBASEiEB1551.
EcoGeneiEG11594. ybeF.

Phylogenomic databases

eggNOGiENOG41064T2. Bacteria.
ENOG4110BBF. LUCA.
HOGENOMiHOG000267879.
OMAiRMTWNES.
PhylomeDBiP30979.

Enzyme and pathway databases

BioCyciEcoCyc:EG11594-MONOMER.
ECOL316407:JW0624-MONOMER.

Miscellaneous databases

PROiP30979.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYBEF_ECOLI
AccessioniPrimary (citable) accession number: P30979
Secondary accession number(s): P75727, P77105
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 127 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.