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P30943

- PHE2_RHDS2

UniProt

P30943 - PHE2_RHDS2

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Protein
Phycoerythrin alpha-2 chain, chloroplastic
Gene
cpeA2
Organism
Rhodomonas sp. (strain CS 24) (Chroomonas sp. (strain CS24))
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei56 – 56115,16-dihydrobiliverdin chromophore (covalent; via 1 link)
Binding sitei58 – 58115,16-dihydrobiliverdin chromophore
Binding sitei78 – 78115,16-dihydrobiliverdin chromophore

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
  2. photosynthesis Source: UniProtKB-KW
  3. protein-chromophore linkage Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Photosynthesis, Transport

Keywords - Ligandi

Bile pigment, Chromophore

Names & Taxonomyi

Protein namesi
Recommended name:
Phycoerythrin alpha-2 chain, chloroplastic
Gene namesi
Name:cpeA2
OrganismiRhodomonas sp. (strain CS 24) (Chroomonas sp. (strain CS24))
Taxonomic identifieri79257 [NCBI]
Taxonomic lineageiEukaryotaCryptophytaPyrenomonadalesPyrenomonadaceaeRhodomonas

Subcellular locationi

GO - Cellular componenti

  1. chloroplast thylakoid membrane Source: UniProtKB-SubCell
  2. phycobilisome Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Membrane, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3737Chloroplast1 Publication
Add
BLAST
Chaini38 – 10467Phycoerythrin alpha-2 chain, chloroplastic
PRO_0000002827Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 4115-hydroxylysine1 Publication

Post-translational modificationi

Contains one covalently linked 15,16-dihydrobiliverdin chromophore.

Keywords - PTMi

Hydroxylation

Interactioni

Subunit structurei

Heterotetramer of 2 different alpha chains and 2 identical beta chains. The subunit composition could comprise of any combination of 2 out of 4 different alpha units with an invariant beta unit.2 Publications

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi44 – 529
Helixi71 – 744
Beta strandi75 – 839
Helixi88 – 10114

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1QGWX-ray1.63B38-104[»]
1XF6X-ray1.10B38-104[»]
1XG0X-ray0.97B38-104[»]
ProteinModelPortaliP30943.
SMRiP30943. Positions 38-104.

Miscellaneous databases

EvolutionaryTraceiP30943.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni61 – 63315,16-dihydrobiliverdin chromophore

Sequence similaritiesi

Belongs to the phycoerythrin family.

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di3.90.510.10. 1 hit.
InterProiIPR011070. Globular_prot_asu/bsu.
IPR004228. Phycoerythr_a_core.
[Graphical view]
PfamiPF02972. Phycoerythr_ab. 1 hit.
[Graphical view]
ProDomiPD019398. Phycoerythr_a/b_core. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF56568. SSF56568. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P30943-1 [UniParc]FASTAAdd to Basket

« Hide

MSAKIIAFSA VVATASAFAP TAGFVPRLRS GATSVNMAMD KSAKAPVITI    50
FDHRGCSRAP KEYTGAKAGG KDDEMMVKAQ SVKIEVSTGT AEGVLATSLA 100
KMTK 104
Length:104
Mass (Da):10,696
Last modified:May 27, 2002 - v2
Checksum:i1474D433E8CB4396
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti63 – 7412YTGAK…GKDDE → TSKSGKSGQDDT AA sequence 1 Publication
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ006994 Genomic DNA. Translation: CAD20039.1.
PIRiT10881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ006994 Genomic DNA. Translation: CAD20039.1 .
PIRi T10881.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1QGW X-ray 1.63 B 38-104 [» ]
1XF6 X-ray 1.10 B 38-104 [» ]
1XG0 X-ray 0.97 B 38-104 [» ]
ProteinModelPortali P30943.
SMRi P30943. Positions 38-104.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei P30943.

Family and domain databases

Gene3Di 3.90.510.10. 1 hit.
InterProi IPR011070. Globular_prot_asu/bsu.
IPR004228. Phycoerythr_a_core.
[Graphical view ]
Pfami PF02972. Phycoerythr_ab. 1 hit.
[Graphical view ]
ProDomi PD019398. Phycoerythr_a/b_core. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF56568. SSF56568. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Nuclear-encoded genes of phycoerythrin alpha subunits."
    Hiller R.G., Howe C.E.
    Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "A genomic clone encoding a cryptophyte phycoerythrin alpha-subunit. Evidence for three alpha-subunits and an N-terminal membrane transit sequence."
    Jenkins J., Hiller R.G., Speirs J., Godovac-Zimmermann J.
    FEBS Lett. 273:191-194(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 38-82.
  3. "Evolution of a light-harvesting protein by addition of new subunits and rearrangement of conserved elements: crystal structure of a cryptophyte phycoerythrin at 1.63-A resolution."
    Wilk K.E., Harrop S.J., Jankova L., Edler D., Keenan G., Sharples F., Hiller R.G., Curmi P.M.
    Proc. Natl. Acad. Sci. U.S.A. 96:8901-8906(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.63 ANGSTROMS) OF 38-104 IN COMPLEX WITH CPEA2; CPEA3 AND 15,16-DIHYDROBILIVERDIN, SUBUNIT, HYDROXYLATION AT LYS-41.
  4. "Developing a structure-function model for the cryptophyte phycoerythrin 545 using ultrahigh resolution crystallography and ultrafast laser spectroscopy."
    Doust A.B., Marai C.N., Harrop S.J., Wilk K.E., Curmi P.M., Scholes G.D.
    J. Mol. Biol. 344:135-153(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (0.97 ANGSTROMS) OF 38-104 IN COMPLEX WITH CPEA2; CPEA3 AND 15,16-DIHYDROBILIVERDIN, SUBUNIT.

Entry informationi

Entry nameiPHE2_RHDS2
AccessioniPrimary (citable) accession number: P30943
Secondary accession number(s): Q8VX02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: May 27, 2002
Last modified: October 16, 2013
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Miscellaneous

The light-harvesting system in Cryptophytes contains phycobiliprotein complexes. Unusually they are composed of either phycoerythrin (CPE) or phycocyanin (CPC) but never allophycocyanin (APC), with only one type of biliprotein being present in any one species. Unlike cyanobacteria or red algae these proteins are not arranged into higher-order phycobilisome complexes, and they are found in the thylakoid lumen.

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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