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P30887 (PHO2_YARLI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acid phosphatase

EC=3.1.3.2
Gene names
Name:PHO2
Ordered Locus Names:YALI0D03465g
OrganismYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) [Reference proteome]
Taxonomic identifier284591 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probably serves to scavenge phosphorus for growing cells.

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor

Magnesium By similarity.

Subcellular location

Secreted.

Sequence similarities

Belongs to the SurE nucleotidase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 358341Acid phosphatase
PRO_0000033476

Sites

Active site1891 Potential
Metal binding491Magnesium By similarity
Metal binding501Magnesium By similarity
Metal binding811Magnesium By similarity
Metal binding1561Magnesium By similarity

Amino acid modifications

Glycosylation201N-linked (GlcNAc...) Potential
Glycosylation271N-linked (GlcNAc...) Potential
Glycosylation321N-linked (GlcNAc...) Potential
Glycosylation921N-linked (GlcNAc...) Potential
Glycosylation1451N-linked (GlcNAc...) Potential
Glycosylation1991N-linked (GlcNAc...) Potential
Glycosylation2781N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict2281G → V in CAA46331. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P30887 [UniParc].

Last modified October 11, 2004. Version 2.
Checksum: 0362F01F892E693B

FASTA35838,003
        10         20         30         40         50         60 
MKFSTIALPL LASAALAQTN SSHSGTNATS HNSTVPNENS KTTIVVTNDD SWASANIRAF 

        70         80         90        100        110        120 
YDELKKEGYN VFMFAPALQQ SGTGGTFVLP KNTTLAKGAE WGSAPVGAPA WGQDEKDDHI 

       130        140        150        160        170        180 
WYFDGTPGAA VTFGFDYALP KFHNNITVDL VVSGPNEGWN LGPFVYTLSG TEGAMYTSVL 

       190        200        210        220        230        240 
RGVPAIAFSG ENKHTYYANA SNSETASHNI YAKASTAIVK NLLKNAKGRP SVLPYGVGLS 

       250        260        270        280        290        300 
VNLPLVGDID PTGKCTDPKP IFTRQTGRGA ITDKLVFNET TGLFKYGDIK SDATKACLNG 

       310        320        330        340        350 
DCFLPDETDV INNWGCYSSI SVVSTDYDAP GALAAEAQFL NRGLVEFAPT GYGSFPGN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X65225 Genomic DNA. Translation: CAA46331.1.
CR382130 Genomic DNA. Translation: CAG80552.1.
PIRS19993.
RefSeqXP_502364.1. XM_502364.1.

3D structure databases

ProteinModelPortalP30887.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCAG80552; CAG80552; YALI0_D03465g.
GeneID2910307.
KEGGyli:YALI0D03465g.

Phylogenomic databases

eggNOGCOG0496.
HOGENOMHOG000248507.
OMANGTHRSF.
OrthoDBEOG79CZ89.

Family and domain databases

Gene3D3.40.1210.10. 1 hit.
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SSF64167. 1 hit.
TIGRFAMsTIGR00087. surE. 1 hit.
ProtoNetSearch...

Entry information

Entry namePHO2_YARLI
AccessionPrimary (citable) accession number: P30887
Secondary accession number(s): Q6CAE8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: October 11, 2004
Last modified: April 16, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families