Reviewed,
UniProtKB/Swiss-Prot P30887 (PHO2_YARLI)
Last modified
June 16, 2009.
Version 54.
History...
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90%,
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Acid phosphatase EC=3.1.3.2 | ||||
| Gene names |
| ||||
| Organism | Yarrowia lipolytica (Candida lipolytica) [Complete proteome] | ||||
| Taxonomic identifier | 4952 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Dipodascaceae › Yarrowia |
Protein attributes
| Sequence length | 358 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Probably serves to scavenge phosphorus for growing cells. |
| Catalytic activity | A phosphate monoester + H2O = an alcohol + phosphate. |
| Cofactor | Magnesium By similarity. |
| Subcellular location | |
| Sequence similarities | Belongs to the surE nucleotidase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Secreted |
| Domain | Signal |
| Ligand | Magnesium Metal-binding |
| Molecular function | Hydrolase |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | acid phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 17 | 17 | Potential | ||||||
| Chain | 18 – 358 | 341 | Acid phosphatase | PRO_0000033476 | |||||
Sites | |||||||||
| Active site | 189 | 1 | Potential | ||||||
| Metal binding | 49 | 1 | Magnesium By similarity | ||||||
| Metal binding | 50 | 1 | Magnesium By similarity | ||||||
| Metal binding | 81 | 1 | Magnesium By similarity | ||||||
| Metal binding | 156 | 1 | Magnesium By similarity | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 20 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 27 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 32 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 92 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 145 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 199 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 278 | 1 | N-linked (GlcNAc...) Potential | ||||||
Experimental info | |||||||||
| Sequence conflict | 228 | 1 | G → V in CAA46331. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Complementation of Saccharomyces cerevisiae acid phosphatase mutation by a genomic sequence from the yeast Yarrowia lipolytica identifies a new phosphatase." Treton B.Y., le Dall M.-T., Gaillardin C. Curr. Genet. 22:345-355(1992) [PubMed: 1423722] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 20460 / W29 / CBS 7504 / IFP29. |
| [2] | "Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. Souciet J.-L.Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIB 122 / E 150. |
Cross-references
Sequence databases | |
|---|---|
| X65225 Genomic DNA. Translation: CAA46331.1. CR382130 Genomic DNA. Translation: CAG80552.1. | |
| PIR | S19993. |
| RefSeq | XP_502364.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2910307. |
| KEGG | yli:YALI0D03465g. |
Phylogenomic databases | |
| HOGENOM | P30887. |
Enzyme and pathway databases | |
| BRENDA | 3.1.3.2. 3602. |
Family and domain databases | |
| InterPro | IPR002828. SurE-like_Pase/nucleotidase. [Graphical view] |
| Gene3D | G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit. |
| Pfam | PF01975. SurE. 1 hit. [Graphical view] |
| ProDom | PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR00087. surE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PHO2_YARLI | ||||||||
| Accession | Primary (citable) accession number: P30887 Secondary accession number(s): Q6CAE8 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||

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