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Protein

ABC transporter arginine-binding protein 1

Gene

artJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Binds L-arginine with high affinity.1 Publication

GO - Molecular functioni

  • amino acid binding Source: EcoliWiki
  • arginine binding Source: EcoCyc
  • ionotropic glutamate receptor activity Source: InterPro

GO - Biological processi

  • arginine transport Source: EcoliWiki

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:ARTJ-MONOMER.
MetaCyc:ARTJ-MONOMER.

Protein family/group databases

TCDBi3.A.1.3.3. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter arginine-binding protein 1
Gene namesi
Name:artJ
Ordered Locus Names:b0860, JW0844
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11628. artJ.

Subcellular locationi

GO - Cellular componenti

  • membrane Source: InterPro
  • outer membrane-bounded periplasmic space Source: EcoCyc
  • periplasmic space Source: EcoliWiki

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 193 PublicationsAdd BLAST19
ChainiPRO_000003175220 – 243ABC transporter arginine-binding protein 1Add BLAST224

Proteomic databases

EPDiP30860.
PaxDbiP30860.
PRIDEiP30860.

2D gel databases

SWISS-2DPAGEiP30860.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (ArtP), two transmembrane proteins (ArtM and ArtQ) and two solute-binding proteins (ArtJ and ArtI).1 Publication

Protein-protein interaction databases

BioGridi4262914. 6 interactors.
IntActiP30860. 1 interactor.
STRINGi316385.ECDH10B_0930.

Structurei

3D structure databases

ProteinModelPortaliP30860.
SMRiP30860.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4106TNF. Bacteria.
COG0834. LUCA.
HOGENOMiHOG000031896.
InParanoidiP30860.
KOiK09996.
PhylomeDBiP30860.

Family and domain databases

InterProiView protein in InterPro
IPR001320. Iontro_rcpt.
IPR005768. Lys_Arg_Orn-bd.
IPR018313. SBP_3_CS.
IPR001638. Solute-binding_3/MltF_N.
PfamiView protein in Pfam
PF00497. SBP_bac_3. 1 hit.
SMARTiView protein in SMART
SM00062. PBPb. 1 hit.
SM00079. PBPe. 1 hit.
TIGRFAMsiTIGR01096. 3A0103s03R. 1 hit.
PROSITEiView protein in PROSITE
PS01039. SBP_BACTERIAL_3. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P30860-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKLVLAALL ASFTFGASAA EKINFGVSAT YPPFESIGAN NEIVGFDIDL
60 70 80 90 100
AKALCKQMQA ECTFTNHAFD SLIPSLKFRK YDAVISGMDI TPERSKQVSF
110 120 130 140 150
TTPYYENSAV VIAKKDTYKT FADLKGKRIG MENGTTHQKY IQDQHPEVKT
160 170 180 190 200
VSYDSYQNAF IDLKNGRIDG VFGDTAVVNE WLKTNPQLGV ATEKVTDPQY
210 220 230 240
FGTGLGIAVR PDNKALLEKL NNALAAIKAD GTYQKISDQW FPQ
Length:243
Mass (Da):26,829
Last modified:November 1, 1997 - v2
Checksum:i4EED7812C5C5DA16
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti128R → C in CAA60105 (PubMed:8501075).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X86160 Genomic DNA. Translation: CAA60105.1.
U00096 Genomic DNA. Translation: AAC73947.1.
AP009048 Genomic DNA. Translation: BAA35574.1.
PIRiD64824.
RefSeqiNP_415381.1. NC_000913.3.
WP_001295339.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73947; AAC73947; b0860.
BAA35574; BAA35574; BAA35574.
GeneIDi948981.
KEGGiecj:JW0844.
eco:b0860.
PATRICifig|1411691.4.peg.1417.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiARTJ_ECOLI
AccessioniPrimary (citable) accession number: P30860
Secondary accession number(s): P77547
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: November 1, 1997
Last modified: July 5, 2017
This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families