Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein Smf

Gene

smf

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Partially complements natural chromosomal DNA transformation defect of an H.influenzae dprA disruption mutant (PubMed:16978360). May help load RecA onto ssDNA (By similarity).By similarity1 Publication

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:EG11604-MONOMER.
ECOL316407:JW5708-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Smf
Gene namesi
Name:smf
Ordered Locus Names:b4473, JW5708
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11604. smf.

Pathology & Biotechi

Disruption phenotypei

No visible effect on transformation or growth in the presence or absence of mitomycin C (in strain KA797), on plasmid conjugation (in strain PC4020), on nucleotide excision repair, survival of UV damage or DNA recombination (PubMed:16978360).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002091571 – 374Protein SmfAdd BLAST374

Proteomic databases

PaxDbiP30852.
PRIDEiP30852.

Interactioni

Protein-protein interaction databases

BioGridi4263397. 17 interactors.
STRINGi511145.b4473.

Structurei

3D structure databases

ProteinModelPortaliP30852.
SMRiP30852.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DprA/Smf family.Curated

Phylogenomic databases

eggNOGiENOG4105C79. Bacteria.
COG0758. LUCA.
HOGENOMiHOG000003906.
InParanoidiP30852.
KOiK04096.
OMAiRTNIPVQ.
PhylomeDBiP30852.

Family and domain databases

InterProiIPR003488. DprA.
[Graphical view]
PfamiPF02481. DNA_processg_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00732. dprA. 1 hit.

Sequencei

Sequence statusi: Complete.

P30852-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVDTEIWLRL MSISSLYGDD MVRIAHWVAK QSHIDAVVLQ QTGLTLRQAQ
60 70 80 90 100
RFLSFPRKSI ESSLCWLEQP NHHLIPADSE FYPPQLLATT DYPGALFVEG
110 120 130 140 150
ELHALHSFQL AVVGSRAHSW YGERWGRLFC ETLATRGVTI TSGLARGIDG
160 170 180 190 200
VAHKAALQVN GVSIAVLGNG LNTIHPRRHA RLAASLLEQG GALVSEFPLD
210 220 230 240 250
VPPLAYNFPR RNRIISGLSK GVLVVEAALR SGSLVTARCA LEQGREVFAL
260 270 280 290 300
PGPIGNPGSE GPHWLIKQGA ILVTEPEEIL ENLQFGLHWL PDAPENSFYS
310 320 330 340 350
PDQQDVALPF PELLANVGDE VTPVDVVAER AGQPVPEVVT QLLELELAGW
360 370
IAAVPGGYVR LRRACHVRRT NVFV
Length:374
Mass (Da):40,955
Last modified:July 1, 1993 - v1
Checksum:i478F522ECB71FA41
GO

Sequence cautioni

The sequence AAA58082 differs from that shown. Reason: Frameshift at position 249.Curated
The sequence AAA58083 differs from that shown. Reason: Frameshift at position 249.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti240A → R in CAA54827 (PubMed:8112305).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65946 Genomic DNA. Translation: CAA46763.1.
X77091 Genomic DNA. Translation: CAA54366.1.
X77800 Genomic DNA. Translation: CAA54827.1.
U18997 Genomic DNA. Translation: AAA58083.1. Frameshift.
U18997 Genomic DNA. Translation: AAA58082.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48176.1.
AP009048 Genomic DNA. Translation: BAE78006.1.
RefSeqiWP_000228551.1. NZ_LN832404.1.
YP_026211.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48176; AAT48176; b4473.
BAE78006; BAE78006; BAE78006.
GeneIDi2847708.
KEGGiecj:JW5708.
eco:b4473.
PATRICi32122004. VBIEscCol129921_3379.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65946 Genomic DNA. Translation: CAA46763.1.
X77091 Genomic DNA. Translation: CAA54366.1.
X77800 Genomic DNA. Translation: CAA54827.1.
U18997 Genomic DNA. Translation: AAA58083.1. Frameshift.
U18997 Genomic DNA. Translation: AAA58082.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48176.1.
AP009048 Genomic DNA. Translation: BAE78006.1.
RefSeqiWP_000228551.1. NZ_LN832404.1.
YP_026211.1. NC_000913.3.

3D structure databases

ProteinModelPortaliP30852.
SMRiP30852.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263397. 17 interactors.
STRINGi511145.b4473.

Proteomic databases

PaxDbiP30852.
PRIDEiP30852.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48176; AAT48176; b4473.
BAE78006; BAE78006; BAE78006.
GeneIDi2847708.
KEGGiecj:JW5708.
eco:b4473.
PATRICi32122004. VBIEscCol129921_3379.

Organism-specific databases

EchoBASEiEB1561.
EcoGeneiEG11604. smf.

Phylogenomic databases

eggNOGiENOG4105C79. Bacteria.
COG0758. LUCA.
HOGENOMiHOG000003906.
InParanoidiP30852.
KOiK04096.
OMAiRTNIPVQ.
PhylomeDBiP30852.

Enzyme and pathway databases

BioCyciEcoCyc:EG11604-MONOMER.
ECOL316407:JW5708-MONOMER.

Miscellaneous databases

PROiP30852.

Family and domain databases

InterProiIPR003488. DprA.
[Graphical view]
PfamiPF02481. DNA_processg_A. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00732. dprA. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSMF_ECOLI
AccessioniPrimary (citable) accession number: P30852
Secondary accession number(s): P76682
, P76683, Q2M6V0, Q47136
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: November 2, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.