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Reviewed, UniProtKB/Swiss-Prot P30799 (DDH_ZYMMO)

Last modified June 16, 2009. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    2-hydroxyacid dehydrogenase homolog
    EC=1.1.1.-
Gene names
Name: ddh
Synonyms: ldhA
Ordered Locus Names: ZMO1237
OrganismZymomonas mobilis [Complete proteome] [HAMAP]
Taxonomic identifier542 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeZymomonas

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3313312-hydroxyacid dehydrogenase homolog
PRO_0000076020

Sites

Active site2361 By similarity
Active site2971Proton donor By similarity

Experimental info

Sequence conflict1841K → E in AAA71934. Ref.1
Sequence conflict2191E → G in AAA71934. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P30799-1 [UniParc].

Last modified February 15, 2005. Version 3.
Checksum: CFEBF136F9FCC4C4

FASTA33136,496
        10         20         30         40         50         60 
MRVAIFSSKN YDHHSIEKEN EHYGHDLVFL NERLTKETAE KAKDAEAVCI FVNDEANAEV 

        70         80         90        100        110        120 
LEILAGLGIK LVALRCAGYN NVDLDAAKKL NIKVVRVPAY SPYSVAEYAV GMLLTLNRQI 

       130        140        150        160        170        180 
SRGLKRVREN NFSLEGLIGL DVHDKTVGII GVGHIGSVFA HIMTHGFGAN VIAYKPHPDP 

       190        200        210        220        230        240 
ELAKKVGFRF TSLDEVIETS DIISLHCPLT PENHHMINEE TLARAKKGFY LVNTSRGGLV 

       250        260        270        280        290        300 
DTKAVIKSLK AKHLGGYAAD VYEEEGPLFF ENHADDIIED DILERLIAFP NVVFTGHQAF 

       310        320        330 
LTKEALSNIA HSILQDISDA EAGKEMPDAL V 

« Hide

References

« Hide 'large scale' references
[1]"Cloning, sequencing, and expression of the Zymomonas mobilis phosphoglycerate mutase gene (pgm) in Escherichia coli."
Yomano L.P., Scopes R.K., Ingram L.O.
J. Bacteriol. 175:3926-3933(1993) [PubMed: 8320209] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 31821 / ZM4 / CP4.
[2]"The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4."
Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y. expand/collapse author list , Kang H.L., Lee S.Y., Lee K.J., Kang H.S.
Nat. Biotechnol. 23:63-68(2005) [PubMed: 15592456] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 31821 / ZM4 / CP4.

Cross-references

Sequence databases

L09650 Genomic DNA. Translation: AAA71934.1.
L09651 Unassigned DNA. Translation: AAA71938.1.
AE008692 Genomic DNA. Translation: AAV89861.1.
PIRD40649.
RefSeqYP_162972.1.

3D structure databases

HSSPHSSP built from PDB template 1J4A based on UniProtKB P26297.
ModBaseSearch...

Genome annotation databases

GeneID3188392.
GenomeReviewsGene locus ZMO1237 in contig AE008692_GR.
KEGGzmo:ZMO1237.
NMPDRfig|264203.3.peg.429.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP30799.
OMAP30799. NERELFF.

Enzyme and pathway databases

BioCycZMOB264203:ZMO1237-MON.

Family and domain databases

InterProIPR006139. D-isomer_2_OHA_DH.
IPR006140. D-isomer_2_OHA_DH_NAD-bd.
[Graphical view]
PfamPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
PROSITEPS00065. D_2_HYDROXYACID_DH_1. 1 hit.
PS00670. D_2_HYDROXYACID_DH_2. 1 hit.
PS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDDH_ZYMMO
AccessionPrimary (citable) accession number: P30799
Secondary accession number(s): Q5NN49
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: February 15, 2005
Last modified: June 16, 2009
This is version 56 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents