P30799 (DDH_ZYMMO) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 75.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: 2-hydroxyacid dehydrogenase homolog EC=1.1.1.- | ||||||
| Gene names |
| ||||||
| Organism | Zymomonas mobilis [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 542 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas |
Protein attributes
| Sequence length | 331 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Sequence similarities | Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Molecular function | NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 331 | 331 | 2-hydroxyacid dehydrogenase homolog | PRO_0000076020 | |||||
Regions | |||||||||
| Nucleotide binding | 154 – 155 | 2 | NAD By similarity | ||||||
| Nucleotide binding | 234 – 236 | 3 | NAD By similarity | ||||||
| Nucleotide binding | 297 – 300 | 4 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 236 | 1 | By similarity | ||||||
| Active site | 265 | 1 | By similarity | ||||||
| Active site | 297 | 1 | Proton donor By similarity | ||||||
| Binding site | 260 | 1 | NAD By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 184 | 1 | K → E in AAA71934. Ref.1 | ||||||
| Sequence conflict | 219 | 1 | E → G in AAA71934. Ref.1 | ||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Cloning, sequencing, and expression of the Zymomonas mobilis phosphoglycerate mutase gene (pgm) in Escherichia coli." Yomano L.P., Scopes R.K., Ingram L.O. J. Bacteriol. 175:3926-3933(1993) [PubMed: 8320209] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 31821 / ZM4 / CP4. |
| [2] | "The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4." Seo J.-S., Chong H., Park H.S., Yoon K.-O., Jung C., Kim J.J., Hong J.H., Kim H., Kim J.-H., Kil J.-I., Park C.J., Oh H.-M., Lee J.-S., Jin S.-J., Um H.-W., Lee H.-J., Oh S.-J., Kim J.Y. Kang H.S.Nat. Biotechnol. 23:63-68(2005) [PubMed: 15592456] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 31821 / ZM4 / CP4. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | L09650 Genomic DNA. Translation: AAA71934.1. L09651 Unassigned DNA. Translation: AAA71938.1. AE008692 Genomic DNA. Translation: AAV89861.1. |
| PIR | D40649. |
| RefSeq | YP_162972.1. NC_006526.2. |
3D structure databases | |
| ProteinModelPortal | P30799. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 3188392. |
| GenomeReviews | Gene locus ZMO1237 in contig AE008692_GR. |
| KEGG | zmo:ZMO1237. |
| NMPDR | fig|264203.3.peg.429. |
| PATRIC | 32567770. VBIZymMob102260_1173. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG731446. |
| OMA | LEFFDFM. |
| ProtClustDB | CLSK2524817. |
Enzyme and pathway databases | |
| BioCyc | ZMOB264203:ZMO1237-MONOMER. |
Family and domain databases | |
| InterPro | IPR006139. D-isomer_2_OHA_DH_cat_dom. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 2 hits. |
| KO | K03778. |
| Pfam | PF00389. 2-Hacid_dh. 1 hit. PF02826. 2-Hacid_dh_C. 1 hit. [Graphical view] |
| PROSITE | PS00065. D_2_HYDROXYACID_DH_1. 1 hit. PS00670. D_2_HYDROXYACID_DH_2. 1 hit. PS00671. D_2_HYDROXYACID_DH_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DDH_ZYMMO | ||||||||
| Accession | Primary (citable) accession number: P30799 Secondary accession number(s): Q5NN49 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with