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Protein

Fibril-forming collagen alpha chain

Gene
N/A
Organism
Riftia pachyptila (Vent tube worm)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Fibril-forming collagen.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei610Imperfection in the GAA repeat1

Names & Taxonomyi

Protein namesi
Recommended name:
Fibril-forming collagen alpha chain
OrganismiRiftia pachyptila (Vent tube worm)
Taxonomic identifieri6426 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaAnnelidaPolychaetaPalpataCanalipalpataSabellidaSiboglinidaeRiftia

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrix, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000059394‹1 – ›1027Fibril-forming collagen alpha chainAdd BLAST›1027

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei214-hydroxyproline; partial1 Publication1
Modified residuei244-hydroxyproline; partial1 Publication1
Modified residuei274-hydroxyproline1 Publication1
Modified residuei394-hydroxyproline1 Publication1
Modified residuei533-hydroxyproline; partial1 Publication1
Modified residuei544-hydroxyproline1 Publication1
Modified residuei724-hydroxyproline; partial1 Publication1
Modified residuei904-hydroxyproline1 Publication1
Modified residuei934-hydroxyproline1 Publication1
Modified residuei965-hydroxylysine1 Publication1
Glycosylationi96O-linked (Gal...) hydroxylysineCurated1
Modified residuei1085-hydroxylysine1 Publication1
Glycosylationi108O-linked (Gal...) hydroxylysineCurated1
Modified residuei1234-hydroxyproline; partial1 Publication1
Modified residuei1284-hydroxyproline; partial1 Publication1
Modified residuei1504-hydroxyproline1 Publication1
Modified residuei1613-hydroxyproline; partial1 Publication1
Modified residuei1624-hydroxyproline1 Publication1
Modified residuei1644-hydroxyproline; partial1 Publication1
Modified residuei1653-hydroxyproline1 Publication1
Modified residuei1744-hydroxyproline1 Publication1
Modified residuei1774-hydroxyproline1 Publication1
Modified residuei1804-hydroxyproline1 Publication1
Modified residuei1835-hydroxylysine1 Publication1
Modified residuei1925-hydroxylysine1 Publication1
Glycosylationi192O-linked (Gal...) hydroxylysineCurated1
Modified residuei2074-hydroxyproline1 Publication1
Modified residuei2164-hydroxyproline1 Publication1
Modified residuei2194-hydroxyproline1 Publication1
Modified residuei2284-hydroxyproline1 Publication1
Modified residuei2374-hydroxyproline1 Publication1
Modified residuei2434-hydroxyproline; partial1 Publication1
Modified residuei2494-hydroxyproline1 Publication1
Modified residuei2554-hydroxyproline1 Publication1
Modified residuei2615-hydroxylysine1 Publication1
Glycosylationi261O-linked (Gal...) hydroxylysineCurated1
Modified residuei2734-hydroxyproline; partial1 Publication1
Modified residuei2764-hydroxyproline; partial1 Publication1
Modified residuei2795-hydroxylysine1 Publication1
Glycosylationi279O-linked (Gal...) hydroxylysineCurated1
Modified residuei2854-hydroxyproline; partial1 Publication1
Modified residuei2914-hydroxyproline; partial1 Publication1
Modified residuei3034-hydroxyproline; partial1 Publication1
Modified residuei3064-hydroxyproline1 Publication1
Modified residuei3124-hydroxyproline1 Publication1
Modified residuei3214-hydroxyproline1 Publication1
Modified residuei3274-hydroxyproline1 Publication1
Modified residuei3394-hydroxyproline1 Publication1
Modified residuei3425-hydroxylysine1 Publication1
Modified residuei3484-hydroxyproline; partial1 Publication1
Modified residuei3515-hydroxylysine; partial1 Publication1
Modified residuei3664-hydroxyproline1 Publication1
Modified residuei3724-hydroxyproline1 Publication1
Modified residuei3754-hydroxyproline1 Publication1
Modified residuei3814-hydroxyproline; partial1 Publication1
Modified residuei3874-hydroxyproline1 Publication1
Modified residuei4163-hydroxyproline; partial1 Publication1
Modified residuei4174-hydroxyproline1 Publication1
Modified residuei4234-hydroxyproline1 Publication1
Modified residuei4294-hydroxyproline1 Publication1
Modified residuei4324-hydroxyproline1 Publication1
Modified residuei4534-hydroxyproline1 Publication1
Modified residuei4654-hydroxyproline1 Publication1
Modified residuei4834-hydroxyproline1 Publication1
Modified residuei5004-hydroxyproline; partial1 Publication1
Modified residuei5034-hydroxyproline; partial1 Publication1
Modified residuei5064-hydroxyproline; partial1 Publication1
Modified residuei5134-hydroxyproline1 Publication1
Modified residuei5254-hydroxyproline1 Publication1
Modified residuei5334-hydroxyproline; partial1 Publication1
Modified residuei5364-hydroxyproline; partial1 Publication1
Modified residuei5404-hydroxyproline1 Publication1
Modified residuei5465-hydroxylysine1 Publication1
Modified residuei5513-hydroxyproline; partial1 Publication1
Modified residuei5524-hydroxyproline1 Publication1
Modified residuei5614-hydroxyproline1 Publication1
Modified residuei5675-hydroxylysine1 Publication1
Modified residuei5735-hydroxylysine1 Publication1
Glycosylationi573O-linked (Gal...) hydroxylysineCurated1
Modified residuei6034-hydroxyproline1 Publication1
Modified residuei6125-hydroxylysine1 Publication1
Glycosylationi612O-linked (Gal...) hydroxylysineCurated1
Modified residuei6214-hydroxyproline; partial1 Publication1
Modified residuei6274-hydroxyproline1 Publication1
Modified residuei6454-hydroxyproline; partial1 Publication1
Modified residuei6473-hydroxyproline; partial1 Publication1
Modified residuei6484-hydroxyproline1 Publication1
Modified residuei6575-hydroxylysine1 Publication1
Glycosylationi657O-linked (Gal...) hydroxylysineCurated1
Modified residuei6634-hydroxyproline1 Publication1
Modified residuei7084-hydroxyproline1 Publication1
Modified residuei7114-hydroxyproline1 Publication1
Modified residuei7144-hydroxyproline1 Publication1
Modified residuei7174-hydroxyproline1 Publication1
Modified residuei7234-hydroxyproline1 Publication1
Modified residuei7385-hydroxylysine1 Publication1
Glycosylationi738O-linked (Gal...) hydroxylysineCurated1
Modified residuei7444-hydroxyproline1 Publication1
Modified residuei7594-hydroxyproline1 Publication1
Modified residuei7655-hydroxylysine1 Publication1
Glycosylationi765O-linked (Gal...) hydroxylysineCurated1
Modified residuei7733-hydroxyproline; partial1 Publication1
Modified residuei7744-hydroxyproline1 Publication1
Modified residuei7834-hydroxyproline1 Publication1
Modified residuei7924-hydroxyproline1 Publication1
Modified residuei8105-hydroxylysine1 Publication1
Glycosylationi810O-linked (Gal...) hydroxylysineCurated1
Modified residuei8153-hydroxyproline; partial1 Publication1
Modified residuei8164-hydroxyproline1 Publication1
Modified residuei8434-hydroxyproline1 Publication1
Modified residuei8494-hydroxyproline1 Publication1
Modified residuei8554-hydroxyproline1 Publication1
Modified residuei8614-hydroxyproline1 Publication1
Modified residuei8674-hydroxyproline1 Publication1
Modified residuei8884-hydroxyproline1 Publication1
Modified residuei8944-hydroxyproline1 Publication1
Modified residuei9034-hydroxyproline1 Publication1
Modified residuei9154-hydroxyproline1 Publication1
Modified residuei9275-hydroxylysine1 Publication1
Glycosylationi927O-linked (Gal...) hydroxylysineCurated1
Modified residuei9335-hydroxylysine; partial1 Publication1
Modified residuei9365-hydroxylysine1 Publication1
Glycosylationi936O-linked (Gal...) hydroxylysineCurated1
Modified residuei9395-hydroxylysine1 Publication1
Modified residuei9454-hydroxyproline1 Publication1
Modified residuei9544-hydroxyproline; partial1 Publication1
Modified residuei9634-hydroxyproline1 Publication1
Modified residuei9664-hydroxyproline1 Publication1
Modified residuei9844-hydroxyproline1 Publication1
Modified residuei9904-hydroxyproline1 Publication1
Modified residuei10103-hydroxyproline; partial1 Publication1
Modified residuei10114-hydroxyproline1 Publication1
Modified residuei10133-hydroxyproline; partial1 Publication1
Modified residuei10144-hydroxyproline1 Publication1
Modified residuei10163-hydroxyproline; partial1 Publication1
Modified residuei10174-hydroxyproline1 Publication1
Modified residuei10193-hydroxyproline; partial1 Publication1
Modified residuei10204-hydroxyproline1 Publication1

Keywords - PTMi

Glycoprotein, Hydroxylation

Proteomic databases

PRIDEiP30754.

Interactioni

Subunit structurei

Homotetramer.

Structurei

3D structure databases

ProteinModelPortaliP30754.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 12Nonhelical region (N-terminal)Add BLAST12
Regioni13 – 1023Triple-helical regionAdd BLAST1011
Regioni1024 – 1027Nonhelical region (C-terminal)4

Keywords - Domaini

Collagen, Repeat

Family and domain databases

InterProiView protein in InterPro
IPR008160. Collagen.
PfamiView protein in Pfam
PF01391. Collagen. 4 hits.

Sequencei

Sequence statusi: Fragment.

P30754-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
YRAGPRYIQA QVGPIGPRGP PGPPGSPGQQ GYQGLRGEPG DSGPMGPIGK
60 70 80 90 100
RGPPGPAGIA GKSGDDGRDG EPGPRGGIGP MGPRGAGGMP GMPGPKGHRG
110 120 130 140 150
FRGLSGSKGE QGKSGNQGPD GGPGPAGPSG PIGPRGQTGE RGRDGKSGLP
160 170 180 190 200
GLRGVDGLAG PPGPPGPIGS TGSPGFPGTP GSKGDRGQSG IKGAQGLQGP
210 220 230 240 250
VGLSGQPGVA GENGHPGMPG MDGANGEPGA SGESGLPGPS GFPGPRGMPG
260 270 280 290 300
TAGSPGQAGA KGDGGPTGEQ GRPGAPGVKG SSGPPGDVGA PGHAGEAGKR
310 320 330 340 350
GSPGSPGPAG SPGPQGDRGL PGSRGLPGMT GASGAMGIPG EKGPSGEPGA
360 370 380 390 400
KGPTGDTGRQ GNQGTPGIAG LPGNPGSDGR PGKDGRPGIR GKDGKQGEQG
410 420 430 440 450
PQGPQGLAGL QGRAGPPGAR GEPGKNGAPG EPGAHGEQGD AGKDGETGAA
460 470 480 490 500
GPPGAAGPTG ARGPPGPRGQ QGFQGLAGAQ GTPGEAGKTG ERGAVGATGP
510 520 530 540 550
SGPAGPGGER GAPGDRGNVG PRGMPGERGA TGPAGPTGSP GVAGAKGQGG
560 570 580 590 600
PPGPAGLVGL PGERGPKGVG GSKGSRGDIG PRGKAGERGK DGERGERGEN
610 620 630 640 650
GLPGPSGLAA SKGERGDMGS PGERGSPGPA GERGPAGSQG IQGQPGPPGD
660 670 680 690 700
AGPAGTKGDI GFPGERGTRG ATGKQGARGP RGLAGKRGLR GAGGSRGETG
710 720 730 740 750
AQGEIGLPGS PGQPGLPGPS GQPGPSGPAG TAGKQGVKGA RGSPGLVGKQ
760 770 780 790 800
GDRGSDGEPG RDGTKGERGE DGPPGVSGPT GAPGQQGERG MPGMVGLRGE
810 820 830 840 850
TGPMGGQGMK GDGGPPGPSG DRGERGNAGP QGPTGPSGQA GAPGQEGAPG
860 870 880 890 900
KDGLPGLAGR PGERGEPGVA GRAGSQGLAG LMGQRGLPGA AGPPGDRGER
910 920 930 940 950
GEPGGQGVQG PVGAPGSQGP AGIMGMKGEA GGKGAKGDKG WTGLPGLQGL
960 970 980 990 1000
QGTPGHSGES GPPGAPGPRG ARGEAGGRGS QGPPGKDGQP GPSGRVGPRG
1010 1020
PSGDDGRSGP PGPPGPPGPP GNSDYGA
Length:1,027
Mass (Da):94,587
Last modified:August 16, 2004 - v2
Checksum:i0555C50E880FDAF6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Sequence uncertaintyi961
Sequence uncertaintyi1081
Sequence uncertaintyi1921
Sequence uncertaintyi2611
Sequence uncertaintyi2791
Sequence uncertaintyi5731
Sequence uncertaintyi6121
Sequence uncertaintyi6571
Sequence uncertaintyi7381
Sequence uncertaintyi7651
Sequence uncertaintyi8101
Sequence uncertaintyi9271
Sequence uncertaintyi9361
Non-terminal residuei10271

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti903P → A. 1

Sequence databases

PIRiS28774.

Similar proteinsi

Entry informationi

Entry nameiCAFF_RIFPA
AccessioniPrimary (citable) accession number: P30754
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: August 16, 2004
Last modified: May 10, 2017
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing