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P30641

- RPAP2_CAEEL

UniProt

P30641 - RPAP2_CAEEL

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Protein
Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2
Gene
R08D7.2
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation By similarity.

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri36 – 12186RTR1-type
Add
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2 (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2
Gene namesi
ORF Names:R08D7.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome III

Organism-specific databases

WormBaseiR08D7.2; CE00290; WBGene00011143.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 455455Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2
PRO_0000065430Add
BLAST

Proteomic databases

PaxDbiP30641.

Interactioni

Protein-protein interaction databases

STRINGi6239.R08D7.2.2.

Structurei

3D structure databases

ProteinModelPortaliP30641.

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG241465.
HOGENOMiHOG000018107.
InParanoidiP30641.
OMAiLPNLDKY.
OrthoDBiEOG7XWPQD.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P30641-1 [UniParc]FASTAAdd to Basket

« Hide

METEIPVNEK ETSFRRRVYT TIETLIDIEN TDQLQEHLPH LHCLGWDEVV    50
EERYVNKQCG FPSCQKAPPK ITRNQMFEID RKEGKIFEFR KQRAKFCSEM 100
CYQKSSFVRK QLDEHPLWIT GLTEARTQKV YEVPDESFVS PIAEKSEPVD 150
SQFKKEPSIW LVTDSIIAKV QDMKLSEEAE EPKSLDPEDQ DIEPFKLTDD 200
DKDFIKSIKE FRNSNFGPPS TSKLLKTAPK PVLSAKDRKK EDEVLAKLRA 250
KYGNKNALQK KPPILIEAQE IHSKLKTMEK AKEAWLVDLI KSWFTPETRK 300
LVREGARPTG GAAEQILMDF LSGKKVDAEK LVNLPNLDKY NVKEKRLNIF 350
LHSIRNHWMD LEARLHLTPT RRDILSRVAS TFQLDSENIT GWTKREINSI 400
VIALFIVICL VDVELGDDYF KKDNASPELT AISNELCGLD SFQITGLHAA 450
IKSQC 455
Length:455
Mass (Da):52,438
Last modified:April 1, 1993 - v1
Checksum:i1FDFADAA58980F3E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z12017 Genomic DNA. Translation: CAA78048.1.
PIRiS41037. S24458.
RefSeqiNP_498983.1. NM_066582.4.
UniGeneiCel.10207.

Genome annotation databases

EnsemblMetazoaiR08D7.2.1; R08D7.2.1; WBGene00011143.
R08D7.2.2; R08D7.2.2; WBGene00011143.
GeneIDi176267.
KEGGicel:CELE_R08D7.2.
UCSCiR08D7.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z12017 Genomic DNA. Translation: CAA78048.1 .
PIRi S41037. S24458.
RefSeqi NP_498983.1. NM_066582.4.
UniGenei Cel.10207.

3D structure databases

ProteinModelPortali P30641.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.R08D7.2.2.

Proteomic databases

PaxDbi P30641.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai R08D7.2.1 ; R08D7.2.1 ; WBGene00011143 .
R08D7.2.2 ; R08D7.2.2 ; WBGene00011143 .
GeneIDi 176267.
KEGGi cel:CELE_R08D7.2.
UCSCi R08D7.2.1. c. elegans.

Organism-specific databases

CTDi 176267.
WormBasei R08D7.2 ; CE00290 ; WBGene00011143 .

Phylogenomic databases

eggNOGi NOG241465.
HOGENOMi HOG000018107.
InParanoidi P30641.
OMAi LPNLDKY.
OrthoDBi EOG7XWPQD.

Miscellaneous databases

NextBioi 891842.
PROi P30641.

Family and domain databases

InterProi IPR007308. DUF408.
[Graphical view ]
Pfami PF04181. RPAP2_Rtr1. 1 hit.
[Graphical view ]
PROSITEi PS51479. ZF_RTR1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiRPAP2_CAEEL
AccessioniPrimary (citable) accession number: P30641
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: June 11, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi