Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2

Gene

R08D7.2

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri36 – 12186RTR1-typeAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2 (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2
Gene namesi
ORF Names:R08D7.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiR08D7.2; CE00290; WBGene00011143.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 455455Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2PRO_0000065430Add
BLAST

Proteomic databases

PaxDbiP30641.

Interactioni

Protein-protein interaction databases

STRINGi6239.R08D7.2.2.

Structurei

3D structure databases

ProteinModelPortaliP30641.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.Curated
Contains 1 RTR1-type zinc finger.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri36 – 12186RTR1-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG241465.
HOGENOMiHOG000018107.
InParanoidiP30641.
OMAiLPNLDKY.
OrthoDBiEOG7XWPQD.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P30641-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METEIPVNEK ETSFRRRVYT TIETLIDIEN TDQLQEHLPH LHCLGWDEVV
60 70 80 90 100
EERYVNKQCG FPSCQKAPPK ITRNQMFEID RKEGKIFEFR KQRAKFCSEM
110 120 130 140 150
CYQKSSFVRK QLDEHPLWIT GLTEARTQKV YEVPDESFVS PIAEKSEPVD
160 170 180 190 200
SQFKKEPSIW LVTDSIIAKV QDMKLSEEAE EPKSLDPEDQ DIEPFKLTDD
210 220 230 240 250
DKDFIKSIKE FRNSNFGPPS TSKLLKTAPK PVLSAKDRKK EDEVLAKLRA
260 270 280 290 300
KYGNKNALQK KPPILIEAQE IHSKLKTMEK AKEAWLVDLI KSWFTPETRK
310 320 330 340 350
LVREGARPTG GAAEQILMDF LSGKKVDAEK LVNLPNLDKY NVKEKRLNIF
360 370 380 390 400
LHSIRNHWMD LEARLHLTPT RRDILSRVAS TFQLDSENIT GWTKREINSI
410 420 430 440 450
VIALFIVICL VDVELGDDYF KKDNASPELT AISNELCGLD SFQITGLHAA

IKSQC
Length:455
Mass (Da):52,438
Last modified:April 1, 1993 - v1
Checksum:i1FDFADAA58980F3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z12017 Genomic DNA. Translation: CAA78048.1.
PIRiS41037. S24458.
RefSeqiNP_498983.1. NM_066582.4.
UniGeneiCel.10207.

Genome annotation databases

EnsemblMetazoaiR08D7.2.1; R08D7.2.1; WBGene00011143.
R08D7.2.2; R08D7.2.2; WBGene00011143.
GeneIDi176267.
KEGGicel:CELE_R08D7.2.
UCSCiR08D7.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z12017 Genomic DNA. Translation: CAA78048.1.
PIRiS41037. S24458.
RefSeqiNP_498983.1. NM_066582.4.
UniGeneiCel.10207.

3D structure databases

ProteinModelPortaliP30641.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.R08D7.2.2.

Proteomic databases

PaxDbiP30641.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiR08D7.2.1; R08D7.2.1; WBGene00011143.
R08D7.2.2; R08D7.2.2; WBGene00011143.
GeneIDi176267.
KEGGicel:CELE_R08D7.2.
UCSCiR08D7.2.1. c. elegans.

Organism-specific databases

CTDi176267.
WormBaseiR08D7.2; CE00290; WBGene00011143.

Phylogenomic databases

eggNOGiNOG241465.
HOGENOMiHOG000018107.
InParanoidiP30641.
OMAiLPNLDKY.
OrthoDBiEOG7XWPQD.

Miscellaneous databases

NextBioi891842.
PROiP30641.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiRPAP2_CAEEL
AccessioniPrimary (citable) accession number: P30641
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.