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P30641 (RPAP2_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2

EC=3.1.3.16
Alternative name(s):
RNA polymerase II-associated protein 2
Gene names
ORF Names:R08D7.2
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation By similarity.

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the RPAP2 family.

Contains 1 RTR1-type zinc finger.

Ontologies

Keywords
   Cellular componentNucleus
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 455455Putative RNA polymerase II subunit B1 CTD phosphatase R08D7.2
PRO_0000065430

Regions

Zinc finger36 – 12186RTR1-type

Sequences

Sequence LengthMass (Da)Tools
P30641 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: 1FDFADAA58980F3E

FASTA45552,438
        10         20         30         40         50         60 
METEIPVNEK ETSFRRRVYT TIETLIDIEN TDQLQEHLPH LHCLGWDEVV EERYVNKQCG 

        70         80         90        100        110        120 
FPSCQKAPPK ITRNQMFEID RKEGKIFEFR KQRAKFCSEM CYQKSSFVRK QLDEHPLWIT 

       130        140        150        160        170        180 
GLTEARTQKV YEVPDESFVS PIAEKSEPVD SQFKKEPSIW LVTDSIIAKV QDMKLSEEAE 

       190        200        210        220        230        240 
EPKSLDPEDQ DIEPFKLTDD DKDFIKSIKE FRNSNFGPPS TSKLLKTAPK PVLSAKDRKK 

       250        260        270        280        290        300 
EDEVLAKLRA KYGNKNALQK KPPILIEAQE IHSKLKTMEK AKEAWLVDLI KSWFTPETRK 

       310        320        330        340        350        360 
LVREGARPTG GAAEQILMDF LSGKKVDAEK LVNLPNLDKY NVKEKRLNIF LHSIRNHWMD 

       370        380        390        400        410        420 
LEARLHLTPT RRDILSRVAS TFQLDSENIT GWTKREINSI VIALFIVICL VDVELGDDYF 

       430        440        450 
KKDNASPELT AISNELCGLD SFQITGLHAA IKSQC 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z12017 Genomic DNA. Translation: CAA78048.1.
PIRS24458. S41037.
RefSeqNP_498983.1. NM_066582.4.
UniGeneCel.10207.

3D structure databases

ProteinModelPortalP30641.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6239.R08D7.2.2.

Proteomic databases

PaxDbP30641.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaR08D7.2.1; R08D7.2.1; R08D7.2.
R08D7.2.2; R08D7.2.2; R08D7.2.
GeneID176267.
KEGGcel:CELE_R08D7.2.
UCSCR08D7.2.1. c. elegans.

Organism-specific databases

CTD176267.
WormBaseR08D7.2; CE00290; WBGene00011143.

Phylogenomic databases

eggNOGNOG241465.
HOGENOMHOG000018107.
InParanoidP30641.
OMALPNLDKY.
OrthoDBEOG7XWPQD.

Family and domain databases

InterProIPR007308. DUF408.
[Graphical view]
PfamPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEPS51479. ZF_RTR1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio891842.
PROP30641.

Entry information

Entry nameRPAP2_CAEEL
AccessionPrimary (citable) accession number: P30641
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: April 16, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

SIMILARITY comments

Index of protein domains and families

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase