P30603 (CHS1_XYLBA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chitin synthase 1
EC=2.4.1.16

Alternative name(s):
Chitin-UDP acetyl-glucosaminyl transferase 1

Gene names

Name:

CHS1

Organism

Xylohypha bantiana

Taxonomic identifier

5590 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Chaetothyriomycetidae › Chaetothyriales › mitosporic Chaetothyriales › Xylohypha

Protein attributes

Sequence length	189 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays a major role in cell wall biogenesis.
Catalytic activity	UDP-N-acetyl-D-glucosamine + (1,4-(N-acetyl-beta-D-glucosaminyl))(n) = UDP + (1,4-(N-acetyl-beta-D-glucosaminyl))(n+1).
Subcellular location	Cell membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the chitin synthase family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Molecular function	Glycosyltransferase Transferase
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW chitin biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	chitin synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›189	›189	Chitin synthase 1		PRO_0000193725
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	189	1

Sequences

	Sequence		Length	Mass (Da)
	P30603 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: 19B6333E682A2EDE	FASTA	189	21,208
	10 20 30 40 50 60 DFLFARTMIG VFKNIEIMCN KGSSQTWGKE AWKKIVVCIV SDRRAKINPR TRAVLAGLGV 70 80 90 100 110 120 YQDGIAKQQV NGKDVTAHIY EYTTQVGIDL KGTQVSLRPK GATPVQLLFC LKEKIRRKIN 130 140 150 160 170 180 SHRWFFQAFG RVLDPNICVL IDAGTKPGKD SIYHLWKAFD LEPMIGGACG EIKVMLEHGK KLYNPLVAT

References

[1]	"Classification of fungal chitin synthases." Bowen A.R., Chen-Wu J.L.-P., Momany M., Young R., Szaniszlo P.J., Robbins P.W. Proc. Natl. Acad. Sci. U.S.A. 89:519-523(1992) [PubMed: 1731323] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M82960 Genomic DNA. Translation: AAC05300.1.
PIR	B45188.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT2. Glycosyltransferase Family 2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR004834. Chitin_synth. [Graphical view]
Pfam	PF01644. Chitin_synth_1. 1 hit. [Graphical view]
ProDom	PD002998. Chitin_synth. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

CHS1_XYLBA

Accession

Primary (citable) accession number: P30603

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	May 31, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program