##gff-version 3
P30560	UniProtKB	Chain	1	424	.	.	.	ID=PRO_0000070201;Note=Vasopressin V1a receptor	
P30560	UniProtKB	Topological domain	1	52	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	53	76	.	.	.	Note=Helical%3B Name%3D1;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	77	88	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	89	110	.	.	.	Note=Helical%3B Name%3D2;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	111	125	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	126	147	.	.	.	Note=Helical%3B Name%3D3;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	148	168	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	169	190	.	.	.	Note=Helical%3B Name%3D4;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	191	220	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	221	241	.	.	.	Note=Helical%3B Name%3D5;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	242	299	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	300	319	.	.	.	Note=Helical%3B Name%3D6;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	320	337	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Transmembrane	338	357	.	.	.	Note=Helical%3B Name%3D7;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Topological domain	358	424	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Region	1	40	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P30560	UniProtKB	Region	383	416	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P30560	UniProtKB	Compositional bias	1	30	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P30560	UniProtKB	Compositional bias	389	416	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P30560	UniProtKB	Modified residue	410	410	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q62463	
P30560	UniProtKB	Lipidation	371	371	.	.	.	Note=S-palmitoyl cysteine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11466323;Dbxref=PMID:11466323	
P30560	UniProtKB	Lipidation	372	372	.	.	.	Note=S-palmitoyl cysteine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11466323;Dbxref=PMID:11466323	
P30560	UniProtKB	Glycosylation	27	27	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P30560	UniProtKB	Disulfide bond	124	205	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00521	
P30560	UniProtKB	Mutagenesis	14	14	.	.	.	Note=Reduced ligand binding affinity. N->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11520055;Dbxref=PMID:11520055	
P30560	UniProtKB	Mutagenesis	27	27	.	.	.	Note=Reduced ligand binding affinity. N->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11520055;Dbxref=PMID:11520055	
P30560	UniProtKB	Mutagenesis	115	115	.	.	.	Note=No significant change in affinity for arginine vasopressin or oxytocin. Increased affinity for 1-deamino%2C D-Arg8-vasopressin. Y->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7774575;Dbxref=PMID:7774575	
P30560	UniProtKB	Mutagenesis	115	115	.	.	.	Note=17-fold increase in affinity for oxytocin. No change in affinity for arginine vasopressin or 1-deamino%2C D-Arg8-vasopressin. Y->F;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7774575;Dbxref=PMID:7774575	
P30560	UniProtKB	Mutagenesis	115	115	.	.	.	Note=50-fold decrease in affinity for arginine vasopressin. Little affect on affinity for oxytocin or 1-deamino%2C D-Arg8-vasopressin. Y->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:7774575;Dbxref=PMID:7774575	
P30560	UniProtKB	Mutagenesis	371	371	.	.	.	Note=Reduced palmitoylation%2C coupling to G protein unaffected. Abolished isoprenylation%2C coupling to G protein unaffected%3B when associated with G-372. C->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11466323;Dbxref=PMID:11466323	
P30560	UniProtKB	Mutagenesis	372	372	.	.	.	Note=Reduced palmitoylation%2C coupling to G protein unaffected. Abolished isoprenylation%2C coupling to G protein unaffected%3B when associated with G-371. C->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11466323;Dbxref=PMID:11466323	
P30560	UniProtKB	Sequence conflict	115	116	.	.	.	Note=YR->SS;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P30560	UniProtKB	Sequence conflict	390	424	.	.	.	Note=RQTSYSNNRSPTNSTGMWKDSPKSSKSIRFIPVST->KTDFLF;Ontology_term=ECO:0000305;evidence=ECO:0000305