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P30556

- AGTR1_HUMAN

UniProt

P30556 - AGTR1_HUMAN

Protein

Type-1 angiotensin II receptor

Gene

AGTR1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 152 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
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    Functioni

    Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

    GO - Molecular functioni

    1. angiotensin type II receptor activity Source: UniProtKB
    2. angiotensin type I receptor activity Source: BHF-UCL
    3. bradykinin receptor binding Source: BHF-UCL
    4. protein binding Source: UniProtKB
    5. protein heterodimerization activity Source: BHF-UCL

    GO - Biological processi

    1. angiotensin-activated signaling pathway Source: GOC
    2. calcium-mediated signaling Source: BHF-UCL
    3. cell chemotaxis Source: UniProtKB
    4. G-protein coupled receptor signaling pathway Source: BHF-UCL
    5. kidney development Source: BHF-UCL
    6. low-density lipoprotein particle remodeling Source: BHF-UCL
    7. phospholipase C-activating angiotensin-activated signaling pathway Source: GOC
    8. phospholipase C-activating G-protein coupled receptor signaling pathway Source: BHF-UCL
    9. positive regulation of cellular protein metabolic process Source: BHF-UCL
    10. positive regulation of cholesterol esterification Source: BHF-UCL
    11. positive regulation of cytosolic calcium ion concentration Source: BHF-UCL
    12. positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway Source: BHF-UCL
    13. positive regulation of inflammatory response Source: BHF-UCL
    14. positive regulation of macrophage derived foam cell differentiation Source: BHF-UCL
    15. positive regulation of NAD(P)H oxidase activity Source: BHF-UCL
    16. positive regulation of phospholipase A2 activity Source: BHF-UCL
    17. positive regulation of reactive oxygen species metabolic process Source: BHF-UCL
    18. regulation of blood vessel size by renin-angiotensin Source: BHF-UCL
    19. regulation of cell growth Source: BHF-UCL
    20. regulation of cell proliferation Source: BHF-UCL
    21. regulation of inflammatory response Source: BHF-UCL
    22. regulation of renal sodium excretion Source: BHF-UCL
    23. regulation of systemic arterial blood pressure by renin-angiotensin Source: BHF-UCL
    24. regulation of vasoconstriction Source: BHF-UCL
    25. regulation of vasodilation Source: BHF-UCL
    26. renin-angiotensin regulation of aldosterone production Source: BHF-UCL
    27. Rho protein signal transduction Source: UniProtKB

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_14819. Peptide ligand-binding receptors.
    REACT_18283. G alpha (q) signalling events.
    SignaLinkiP30556.

    Protein family/group databases

    TCDBi9.A.14.13.1. the g-protein-coupled receptor (gpcr) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Type-1 angiotensin II receptor
    Alternative name(s):
    AT1AR
    AT1BR
    Angiotensin II type-1 receptor
    Short name:
    AT1
    Gene namesi
    Name:AGTR1
    Synonyms:AGTR1A, AGTR1B, AT2R1, AT2R1B
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:336. AGTR1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB
    2. integral component of plasma membrane Source: BHF-UCL
    3. plasma membrane Source: UniProtKB

    Keywords - Cellular componenti

    Cell membrane, Membrane

    Pathology & Biotechi

    Involvement in diseasei

    Renal tubular dysgenesis (RTD) [MIM:267430]: Autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).1 Publication
    Note: The disease is caused by mutations affecting the gene represented in this entry.
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti282 – 2821T → M in RTD. 1 Publication
    VAR_035086

    Keywords - Diseasei

    Disease mutation

    Organism-specific databases

    MIMi267430. phenotype.
    Orphaneti97369. Renal tubular dysgenesis of genetic origin.
    PharmGKBiPA43.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 359359Type-1 angiotensin II receptorPRO_0000069153Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi4 – 41N-linked (GlcNAc...) (complex)1 Publication
    Disulfide bondi101 ↔ 180PROSITE-ProRule annotation
    Glycosylationi176 – 1761N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi188 – 1881N-linked (GlcNAc...)Sequence Analysis
    Lipidationi355 – 3551S-palmitoyl cysteineSequence Analysis

    Post-translational modificationi

    C-terminal Ser or Thr residues may be phosphorylated.

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein

    Proteomic databases

    PaxDbiP30556.
    PRIDEiP30556.

    PTM databases

    PhosphoSiteiP30556.

    Expressioni

    Tissue specificityi

    Liver, lung, adrenal and adrenocortical adenomas.

    Gene expression databases

    ArrayExpressiP30556.
    BgeeiP30556.
    CleanExiHS_AGTR1.
    GenevestigatoriP30556.

    Organism-specific databases

    HPAiHPA003596.

    Interactioni

    Subunit structurei

    Interacts with MAS1 Probable. Interacts with ARRB1 By similarity.By similarityCurated

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    AGTP010192EBI-6623016,EBI-6622938

    Protein-protein interaction databases

    BioGridi106691. 13 interactions.
    IntActiP30556. 5 interactions.
    MINTiMINT-107041.
    STRINGi9606.ENSP00000273430.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1ZV0model-B1-359[»]
    ProteinModelPortaliP30556.
    SMRiP30556. Positions 27-318.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2727ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini53 – 6412CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini88 – 10215ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini125 – 14218CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini163 – 19230ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini215 – 24026CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini263 – 27513ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini297 – 35963CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei28 – 5225Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei65 – 8723Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei103 – 12422Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei143 – 16220Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei193 – 21422Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei241 – 26222Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei276 – 29621Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG256015.
    HOVERGENiHBG104998.
    InParanoidiP30556.
    KOiK04166.
    OMAiCIVIWLL.
    OrthoDBiEOG7J4473.
    PhylomeDBiP30556.
    TreeFamiTF330024.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000190. ATII_AT1_rcpt.
    IPR000248. ATII_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00241. ANGIOTENSINR.
    PR00635. ANGIOTENSN1R.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P30556-1 [UniParc]FASTAAdd to Basket

    « Hide

    MILNSSTEDG IKRIQDDCPK AGRHNYIFVM IPTLYSIIFV VGIFGNSLVV    50
    IVIYFYMKLK TVASVFLLNL ALADLCFLLT LPLWAVYTAM EYRWPFGNYL 100
    CKIASASVSF NLYASVFLLT CLSIDRYLAI VHPMKSRLRR TMLVAKVTCI 150
    IIWLLAGLAS LPAIIHRNVF FIENTNITVC AFHYESQNST LPIGLGLTKN 200
    ILGFLFPFLI ILTSYTLIWK ALKKAYEIQK NKPRNDDIFK IIMAIVLFFF 250
    FSWIPHQIFT FLDVLIQLGI IRDCRIADIV DTAMPITICI AYFNNCLNPL 300
    FYGFLGKKFK RYFLQLLKYI PPKAKSHSNL STKMSTLSYR PSDNVSSSTK 350
    KPAPCFEVE 359
    Length:359
    Mass (Da):41,061
    Last modified:April 1, 1993 - v1
    Checksum:i35FC856F53E911A6
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti187 – 1871Q → R in BAA02968. (PubMed:8135787)Curated
    Sequence conflicti204 – 2052FL → SC in BAA02968. (PubMed:8135787)Curated
    Sequence conflicti232 – 2321K → N in BAA02968. (PubMed:8135787)Curated
    Sequence conflicti240 – 2401K → R in BAA02968. (PubMed:8135787)Curated
    Sequence conflicti268 – 2681L → Q in BAA02968. (PubMed:8135787)Curated
    Sequence conflicti311 – 3133RYF → KDI in BAA02968. (PubMed:8135787)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti48 – 481L → V.
    Corresponds to variant rs2011425 [ dbSNP | Ensembl ].
    VAR_011846
    Natural varianti163 – 1631A → T.
    Corresponds to variant rs12721226 [ dbSNP | Ensembl ].
    VAR_029206
    Natural varianti222 – 2221L → V.1 Publication
    Corresponds to variant rs17852013 [ dbSNP | Ensembl ].
    VAR_070375
    Natural varianti244 – 2441A → S.
    Corresponds to variant rs12721225 [ dbSNP | Ensembl ].
    VAR_029207
    Natural varianti282 – 2821T → M in RTD. 1 Publication
    VAR_035086
    Natural varianti289 – 2891C → W.1 Publication
    Corresponds to variant rs1064533 [ dbSNP | Ensembl ].
    VAR_011847
    Natural varianti336 – 3361T → P.
    Corresponds to variant rs1801021 [ dbSNP | Ensembl ].
    VAR_011848
    Natural varianti341 – 3411P → H.1 Publication
    Corresponds to variant rs17852012 [ dbSNP | Ensembl ].
    VAR_070376

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M91464 Genomic DNA. Translation: AAA35569.1.
    Z11162 Genomic DNA. Translation: CAA77513.1.
    M87290 mRNA. Translation: AAA35535.1.
    S77410 mRNA. Translation: AAB34644.1.
    M93394 mRNA. Translation: AAA58370.1.
    D13814 mRNA. Translation: BAA02968.1.
    X65699 mRNA. Translation: CAA46621.1.
    AF245699 Genomic DNA. Translation: AAF70464.1.
    AY221090 Genomic DNA. Translation: AAO65968.1.
    BC022447 mRNA. Translation: AAH22447.1.
    CCDSiCCDS3137.1.
    PIRiI39418.
    JC1104.
    RefSeqiNP_000676.1. NM_000685.4.
    NP_004826.5. NM_004835.4.
    NP_033611.1. NM_009585.3.
    UniGeneiHs.477887.
    Hs.744837.

    Genome annotation databases

    EnsembliENST00000349243; ENSP00000273430; ENSG00000144891.
    ENST00000402260; ENSP00000385641; ENSG00000144891.
    ENST00000404754; ENSP00000385612; ENSG00000144891.
    ENST00000418473; ENSP00000398832; ENSG00000144891.
    ENST00000461609; ENSP00000418851; ENSG00000144891.
    ENST00000474935; ENSP00000418084; ENSG00000144891.
    ENST00000475347; ENSP00000419783; ENSG00000144891.
    ENST00000497524; ENSP00000419422; ENSG00000144891.
    GeneIDi185.
    KEGGihsa:185.
    UCSCiuc003ewi.3. human.

    Polymorphism databases

    DMDMi231519.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Web resourcesi

    SHMPD

    The Singapore human mutation and polymorphism database

    Wikipedia

    Angiotensin receptor entry

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M91464 Genomic DNA. Translation: AAA35569.1 .
    Z11162 Genomic DNA. Translation: CAA77513.1 .
    M87290 mRNA. Translation: AAA35535.1 .
    S77410 mRNA. Translation: AAB34644.1 .
    M93394 mRNA. Translation: AAA58370.1 .
    D13814 mRNA. Translation: BAA02968.1 .
    X65699 mRNA. Translation: CAA46621.1 .
    AF245699 Genomic DNA. Translation: AAF70464.1 .
    AY221090 Genomic DNA. Translation: AAO65968.1 .
    BC022447 mRNA. Translation: AAH22447.1 .
    CCDSi CCDS3137.1.
    PIRi I39418.
    JC1104.
    RefSeqi NP_000676.1. NM_000685.4.
    NP_004826.5. NM_004835.4.
    NP_033611.1. NM_009585.3.
    UniGenei Hs.477887.
    Hs.744837.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1ZV0 model - B 1-359 [» ]
    ProteinModelPortali P30556.
    SMRi P30556. Positions 27-318.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 106691. 13 interactions.
    IntActi P30556. 5 interactions.
    MINTi MINT-107041.
    STRINGi 9606.ENSP00000273430.

    Chemistry

    BindingDBi P30556.
    ChEMBLi CHEMBL227.
    DrugBanki DB00796. Candesartan.
    DB00876. Eprosartan.
    DB01342. Forasartan.
    DB01029. Irbesartan.
    DB00678. Losartan.
    DB00275. Olmesartan.
    DB01347. Saprisartan.
    DB00421. Spironolactone.
    DB01349. Tasosartan.
    DB00966. Telmisartan.
    DB00177. Valsartan.
    GuidetoPHARMACOLOGYi 34.

    Protein family/group databases

    TCDBi 9.A.14.13.1. the g-protein-coupled receptor (gpcr) family.
    GPCRDBi Search...

    PTM databases

    PhosphoSitei P30556.

    Polymorphism databases

    DMDMi 231519.

    Proteomic databases

    PaxDbi P30556.
    PRIDEi P30556.

    Protocols and materials databases

    DNASUi 185.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000349243 ; ENSP00000273430 ; ENSG00000144891 .
    ENST00000402260 ; ENSP00000385641 ; ENSG00000144891 .
    ENST00000404754 ; ENSP00000385612 ; ENSG00000144891 .
    ENST00000418473 ; ENSP00000398832 ; ENSG00000144891 .
    ENST00000461609 ; ENSP00000418851 ; ENSG00000144891 .
    ENST00000474935 ; ENSP00000418084 ; ENSG00000144891 .
    ENST00000475347 ; ENSP00000419783 ; ENSG00000144891 .
    ENST00000497524 ; ENSP00000419422 ; ENSG00000144891 .
    GeneIDi 185.
    KEGGi hsa:185.
    UCSCi uc003ewi.3. human.

    Organism-specific databases

    CTDi 185.
    GeneCardsi GC03P148415.
    HGNCi HGNC:336. AGTR1.
    HPAi HPA003596.
    MIMi 106165. gene.
    267430. phenotype.
    neXtProti NX_P30556.
    Orphaneti 97369. Renal tubular dysgenesis of genetic origin.
    PharmGKBi PA43.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG256015.
    HOVERGENi HBG104998.
    InParanoidi P30556.
    KOi K04166.
    OMAi CIVIWLL.
    OrthoDBi EOG7J4473.
    PhylomeDBi P30556.
    TreeFami TF330024.

    Enzyme and pathway databases

    Reactomei REACT_14819. Peptide ligand-binding receptors.
    REACT_18283. G alpha (q) signalling events.
    SignaLinki P30556.

    Miscellaneous databases

    GeneWikii Angiotensin_II_receptor_type_1.
    GenomeRNAii 185.
    NextBioi 752.
    PROi P30556.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P30556.
    Bgeei P30556.
    CleanExi HS_AGTR1.
    Genevestigatori P30556.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000190. ATII_AT1_rcpt.
    IPR000248. ATII_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00241. ANGIOTENSINR.
    PR00635. ANGIOTENSN1R.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning, expression, and characterization of a gene encoding the human angiotensin II type 1A receptor."
      Mauzy C.A., Hwang O., Egloff A.M., Wu L.H., Chung F.-Z.
      Biochem. Biophys. Res. Commun. 186:277-284(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Molecular cloning and sequencing of the gene encoding human angiotensin II type 1 receptor."
      Furuta H., Guo D.F., Inagami T.
      Biochem. Biophys. Res. Commun. 183:8-13(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Tissue: Lymphocyte.
    3. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Liver.
    4. "Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor."
      Takayanagi R., Ohnaka K., Sakai Y., Nakao R., Yanase T., Haji M., Inagami T., Furuta H., Gou D.F., Nakamuta M., Nawata H.
      Biochem. Biophys. Res. Commun. 183:910-916(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Liver.
    5. "Genetic analysis of the human type-1 angiotensin II receptor."
      Curnow K.M., Pascoe L., White P.C.
      Mol. Endocrinol. 6:1113-1118(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    6. "Novel subtype of human angiotensin II type 1 receptor: cDNA cloning and expression."
      Konishi H., Kuroda S., Inada Y., Fujisawa Y.
      Biochem. Biophys. Res. Commun. 199:467-474(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT TRP-289.
      Tissue: Placenta.
    7. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Liver.
    8. "Cloning and sequencing of a human cDNA encoding the angiotensin II receptor type 1."
      Ostermann E., Castanon M.J.
      Submitted (JUL-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Placenta.
    9. "Rapid identification of polymorphisms in genomic DNA: a high density SNP map of the type I angiotensin II receptor gene locus on chromosome 3q."
      Antonellis A., Rogus J.J., Pezzolesi M.G., Makita Y., Nam M., Doria A., Warram J.H., Krolewski A.S.
      Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    10. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A., Aronstam R.S., Sharma S.V.
      Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS VAL-222 AND HIS-341.
      Tissue: Brain.
    12. Cited for: INTERACTION WITH MAS1.
    13. Cited for: GLYCOSYLATION AT ASN-4.
    14. Cited for: VARIANT RTD MET-282.

    Entry informationi

    Entry nameiAGTR1_HUMAN
    AccessioniPrimary (citable) accession number: P30556
    Secondary accession number(s): Q13725, Q8TBK4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 152 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    6. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    7. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3