P30355Q9D138AL5AP_MOUSEArachidonate 5-lipoxygenase-activating proteinFLAPMK-886-binding proteinAlox5apFlapMus musculusMouseEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMusThe transcriptional landscape of the mammalian genome.NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]Cross-species comparison of 5-lipoxygenase-activating protein.NUCLEOTIDE SEQUENCE [MRNA] OF 1-153The nuclear membrane organization of leukotriene synthesis.SUBCELLULAR LOCATIONFUNCTIONINTERACTION WITH ALOX5A tissue-specific atlas of mouse protein phosphorylation and expression.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity).Homotrimer. Interacts with LTC4S and ALOX5.Nucleus membraneMulti-pass membrane proteinEndoplasmic reticulum membraneMulti-pass membrane proteinThe C-terminal part after residue 140 is mostly disordered.Belongs to the MAPEG family.Endoplasmic reticulumLeukotriene biosynthesisMembraneNucleusReference proteomeTransmembraneTransmembrane helixDYMDQEAVGNVVLLALVTLISVVQNAFFAHKVEHESKAHNGRSFQRTGTLAFERVYTANQNCVDAYPTFLVVLWTAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSFAGILNHYLIFFFGSDFENYIRTVSTTISPLLLIP
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