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P30265 (CATA_LACSK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Catalase
EC=1.11.1.6
Gene names
Name:katA
OrganismLactobacillus sakei
Taxonomic identifier1599 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length478 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activity

2 H2O2 = O2 + 2 H2O.

Cofactor

Heme group.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the catalase family.

Ontologies

Keywords
   Biological processHydrogen peroxide
   Cellular componentCytoplasm
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
Gene Ontology (GO)
   Biological processhydrogen peroxide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncatalase activity

Inferred from electronic annotation. Source: EC

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 478478Catalase
PRO_0000084989

Sites

Active site531 By similarity
Active site1261 By similarity
Metal binding3361Iron (heme axial ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
P30265 [UniParc].

Last modified July 15, 1999. Version 2.
Checksum: 85952A05DB16EF3D

FASTA47854,076
        10         20         30         40         50         60 
MTNQLTTNEG QPWADNQHSQ TAGQRGPVLI QDYQLLEKLA HFNRERIPER VVHAKGAGAK 

        70         80         90        100        110        120 
GYFKVTKDMS AYTKAAVFSG VGKKTPLITR FSQVAGEAGY PDTYRDVRGF AVKFYTEEGN 

       130        140        150        160        170        180 
YDIVGNNTPV FFVNDPLKFP DFIHSQKRDP RTHARSQDMQ WDFWSLSPES VHQVTILMSD 

       190        200        210        220        230        240 
RGIPASYRMM HGFGSHTFKW VNAQGEQFWV KYHFKTNQGI HNLSNELADE LAGKDTDYLQ 

       250        260        270        280        290        300 
NDLFDAIETG DYPSWTVAVQ LVPYEDGLNY PQDIFDVTKV ISQKDYPLIE IGQMVLDENP 

       310        320        330        340        350        360 
TNNFEDIQEL AFSPANLVPG IEASPDKLLQ GRLFGYKDAE RYRLGANYEQ LPVNRPKVPV 

       370        380        390        400        410        420 
HNYERDGAMA QNQATGVNYE PNSQDGPTEV PAAKIHGDQL SGTTGNFSAD PDYYSAAGKL 

       430        440        450        460        470 
YRLLSADEQT RLIENIRMNL GQVTKPEIQI REVKQFYQAD PEYGRRVATS VKLRFSSV

« Hide

References

[1]"Cloning, sequence, and phenotypic expression of katA, which encodes the catalase of Lactobacillus sake LTH677."
Knauf H.J., Vogel R.F., Hammes W.P.
Appl. Environ. Microbiol. 58:832-839(1992) [PubMed: 1575485] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LTH677.
[2]"Oxygen-dependent regulation of the expression of the catalase gene katA of Lactobacillus sakei LTH677."
Hertel C., Schmidt G., Fischer M., Oellers K., Hammes W.P.
Appl. Environ. Microbiol. 64:1359-1365(1998) [PubMed: 9546173] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SEQUENCE REVISION.
Strain: LTH677.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		M84015 Genomic DNA. Translation: AAC19139.1.
PIRT09652.

3D structure databases

ProteinModelPortalP30265.
SMRP30265. Positions 4-472.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024711. Catalase_clade1/3.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
[Graphical view]
Gene3DG3DSA:2.40.180.10. Catalase_N. 1 hit.
PANTHERPTHR11465. Catalase. 1 hit.
PfamPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFPIRSF038928. Catalase_clade1-3. 1 hit.
PRINTSPR00067. CATALASE.
SMARTSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMSSF56634. Catalase_N. 1 hit.
PROSITEPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCATA_LACSK
AccessionPrimary (citable) accession number: P30265
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: July 15, 1999
Last modified: January 25, 2012
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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