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Reviewed, UniProtKB/Swiss-Prot P30187 (CML10_ARATH)

Last modified June 16, 2009. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Calmodulin-like protein 10
Alternative name(s):
    22 kDa calmodulin-like calcium-binding protein
    CABP-22
Gene names
Name: CML10
Ordered Locus Names: At2g41090
ORF Names: T3K9.14
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis

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Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Function

Potential calcium sensor.

Tissue specificity

Specifically expressed in leaves.

Induction

By touch. Ref.6

Sequence similarities

Belongs to the calmodulin family.

Contains 4 EF-hand domains.

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Ontologies

Keywords
   DomainRepeat
   LigandCalcium
   PTMMethylation
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functioncalcium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

protein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

O221791EBI-1238722,EBI-1238013
P274501EBI-1238722,EBI-1238108
Q29Q721EBI-1238722,EBI-1238714
Q2V3591EBI-1238722,EBI-1235819
Q3EAG31EBI-1238722,EBI-1238312
Q3EBV71EBI-1238722,EBI-1235683
Q4PSE31EBI-1238722,EBI-1238507
Q7X9H61EBI-1238722,EBI-1238497
Q7X9N21EBI-1238722,EBI-622264
Q84WW11EBI-1238722,EBI-1238751
Q8H1D61EBI-1238722,EBI-1238166
Q8LPR41EBI-1238722,EBI-1238087
Q8VZ701EBI-1238722,EBI-1238078
Q8VZK41EBI-1238722,EBI-1238776
Q93Z301EBI-1238722,EBI-1237782
Q9FGX21EBI-1238722,EBI-942623
Q9FGZ51EBI-1238722,EBI-622281
Q9FIW61EBI-1238722,EBI-1237967
Q9FL191EBI-1238722,EBI-622440
Q9FLL01EBI-1238722,EBI-1238516
Q9FLV41EBI-1238722,EBI-1238700
Q9FME91EBI-1238722,EBI-1238771
Q9FUD31EBI-1238722,EBI-942633
Q9LW451EBI-1238722,EBI-942952
Q9LW661EBI-1238722,EBI-1238066
Q9LX561EBI-1238722,EBI-1235891
Q9SGN71EBI-1238722,EBI-1238190
Q9SJX81EBI-1238722,EBI-1238001
Q9SKN21EBI-1238722,EBI-1237944
Q9SL701EBI-1238722,EBI-1238421
ABF4Q9M7Q21EBI-1238722,EBI-1237867
AFRQ8LAW21EBI-1238722,EBI-604438
AGL15Q388471EBI-1238722,EBI-622076
AGL21Q9SZJ61EBI-1238722,EBI-621986
AGL61Q4PSU41EBI-1238722,EBI-1237976
AGL80Q9FJK31EBI-1238722,EBI-622424
ALDH3F1Q70E961EBI-1238722,EBI-1237774
APK2aO498391EBI-1238722,EBI-1238631
ASK6Q390101EBI-1238722,EBI-1238323
At1g08320Q56W431EBI-1238722,EBI-1237844
At1g27190O045671EBI-1238722,EBI-1238687
At1g54610Q9ZVM91EBI-1238722,EBI-1235713
At1g58110Q84WC81EBI-1238722,EBI-1237819
At1g60040Q9ZUI91EBI-1238722,EBI-622185
At1g68380/T2E12_7Q9M9C31EBI-1238722,EBI-1238618
At1g77145O806511EBI-1238722,EBI-1238133
At1g80120Q9SSC71EBI-1238722,EBI-1238625
At3g02880Q9M8T01EBI-1238722,EBI-1238677
At3g17600Q2VW981EBI-1238722,EBI-1235997
At3g19100Q9LJL91EBI-1238722,EBI-1238393
AT4g02410O812921EBI-1238722,EBI-1237950
AT4g02640O227631EBI-1238722,EBI-969959
AT4g34380Q9SZ031EBI-1238722,EBI-1238343
At4g37240/C7A10_120Q8LE561EBI-1238722,EBI-1237996
At4g39540/F23K16_170Q8GY881EBI-1238722,EBI-1238334
At5g37670/K12B20_120Q9FHQ31EBI-1238722,EBI-1238761
At5g38800Q9FMC21EBI-1238722,EBI-1237855
At5g49760/K2I5_13Q8GZ991EBI-1238722,EBI-1238218
AtMg00870P925251EBI-1238722,EBI-1238547
BZIP61Q9M2K41EBI-1238722,EBI-1237830
CAX2Q392541EBI-1238722,EBI-1238729
CDKB2-2Q8LG641EBI-1238722,EBI-1235761
CIPK24Q9LDI31EBI-1238722,EBI-537551
CIPK6O655541EBI-1238722,EBI-537615
CKI1Q390501EBI-1238722,EBI-1237881
CML45Q93Z271EBI-1238722,EBI-1235938
CPK3Q424791EBI-1238722,EBI-1235782
CPK30Q9SSF81EBI-1238722,EBI-1235738
CRK40Q9SYS31EBI-1238722,EBI-1238119
CRK9O654691EBI-1238722,EBI-1238158
CYP705A20Q9LJY71EBI-1238722,EBI-1237907
CYP78A9Q9SLP11EBI-1238722,EBI-1238437
dl4570wO235521EBI-1238722,EBI-1235805
F11C1_150Q9SND61EBI-1238722,EBI-1235872
F14F8_210Q9LFU31EBI-1238722,EBI-1237805
F18O21_230Q9LYL61EBI-1238722,EBI-1238139
FBW2Q9ZPE41EBI-1238722,EBI-604740
FBX14Q8RWQ81EBI-1238722,EBI-1235922
HSP81-2P557371EBI-1238722,EBI-1235834
JAC1Q9C9Q41EBI-1238722,EBI-1238741
LRR-RLKQ3ECN41EBI-1238722,EBI-1238268
LRR-RLKQ8VYG71EBI-1238722,EBI-1238236
LRR-RLKQ9LSI91EBI-1238722,EBI-1238253
LRR-RLKQ9M9C51EBI-1238722,EBI-1238661
MHKP432941EBI-1238722,EBI-1238022
MPK18Q9C5C01EBI-1238722,EBI-1238534
NEK7Q9LHI71EBI-1238722,EBI-1238055
PCKAQ9T0741EBI-1238722,EBI-1238593
PEPKR2Q8W4901EBI-1238722,EBI-1238381
PFK2Q9FIK01EBI-1238722,EBI-1238609
psbAP837551EBI-1238722,EBI-1236013
RKF3P930501EBI-1238722,EBI-1238281
SCL4Q9FL031EBI-1238722,EBI-1238466
SHP1Q5XXJ31EBI-1238722,EBI-1237985
T12C14_120Q9LZP81EBI-1238722,EBI-942845
T20L15_160Q9LZV71EBI-1238722,EBI-1238200
T4M14.10Q9LQ651EBI-1238722,EBI-942986
TGA4Q391621EBI-1238722,EBI-541600
TT16Q8RYD91EBI-1238722,EBI-621993
WAKL21Q8GYF51EBI-1238722,EBI-1238355
WRKY43Q8GY111EBI-1238722,EBI-1235953
WRKY53Q9SUP61EBI-1238722,EBI-1235980

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 191191Calmodulin-like protein 10
PRO_0000073658

Regions

Domain8 – 4336EF-hand 1
Domain44 – 7734EF-hand 2
Domain78 – 11336EF-hand 3
Domain114 – 14936EF-hand 4
Calcium binding21 – 32121 Potential
Calcium binding57 – 68122 Potential
Calcium binding91 – 102123 Potential
Calcium binding127 – 138124 Potential

Amino acid modifications

Modified residue1131N6,N6,N6-trimethyllysine By similarity

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Sequences

Sequence LengthMass (Da)Tools
P30187-1 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: 571F40C1E64370A8

FASTA19121,727
        10         20         30         40         50         60 
MANKFTRQQI SEFREQFSVY DKNGDGHITT EEFGAVMRSL GLNLTQAELQ EEINDSDLDG 

        70         80         90        100        110        120 
DGTINFTEFL CAMAKDTYSE KDLKKDFRLF DIDKNGFISA AEMRYVRTIL RWKQTDEEID 

       130        140        150        160        170        180 
EIIKAADVDG DGQINYREFA RLMMAKNQGH DTKYDTTGGT LERDLAAGVA KNIIAAPMTD 

       190 
FIKNLFEALF S

« Hide

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References

« Hide 'large scale' references
[1]"Isolation of an Arabidopsis cDNA sequence encoding a 22 kDa calcium-binding protein (CaBP-22) related to calmodulin."
Ling V., Zielinski R.E.
Plant Mol. Biol. 22:207-214(1993) [PubMed: 8507824] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
Tissue: Leaf.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed: 10617197] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed: 14593172] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Calmodulins and related potential calcium sensors of Arabidopsis."
McCormack E., Braam J.
New Phytol. 159:585-598(2003)
Cited for: GENE FAMILY, NOMENCLATURE.
[6]"Genome-wide identification of touch- and darkness-regulated Arabidopsis genes: a focus on calmodulin-like and XTH genes."
Lee D., Polisensky D.H., Braam J.
New Phytol. 165:429-444(2005) [PubMed: 15720654] [Abstract]
Cited for: INDUCTION.

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Cross-references

Sequence databases

Z12136 mRNA. Translation: CAA78124.1.
AC004261 Genomic DNA. Translation: AAD12002.1.
AY046044 mRNA. Translation: AAK76718.1.
AY084987 mRNA. Translation: AAM61546.1.
IPIIPI00548265.
PIRS35188.
RefSeqNP_181642.1.
UniGeneAt.12547

3D structure databases

HSSPHSSP built from PDB template 1CDM based on UniProtKB P02593.
ModBaseSearch...

Protein-protein interaction databases

IntActP30187. 102 interactions.

Proteomic databases

PRIDEP30187.

Genome annotation databases

GeneID818708.
GenomeReviewsGene locus AT2G41090 in contig CT485783_GR.
KEGGath:AT2G41090.
NMPDRfig|3702.1.peg.11246.

Organism-specific databases

TAIRAt2g41090.

Gene expression databases

ArrayExpressP30187.
GermOnlineAT2G41090. Arabidopsis thaliana.

Family and domain databases

InterProIPR011992. EF-Hand_type.
IPR018248. EF_hand.
IPR018247. EF_HAND_1.
IPR018249. EF_HAND_2.
IPR002048. EF_hand_Ca_bd.
[Graphical view]
Gene3DG3DSA:1.10.238.10. EF-Hand_type. 1 hit.
PfamPF00036. efhand. 4 hits.
[Graphical view]
ProDomPD000012. EF-hand. 2 hits.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00054. EFh. 4 hits.
[Graphical view]
PROSITEPS00018. EF_HAND_1. 4 hits.
PS50222. EF_HAND_2. 4 hits.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameCML10_ARATH
AccessionPrimary (citable) accession number: P30187
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: June 16, 2009
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

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Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents