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P30180

- AACC7_STRRY

UniProt

P30180 - AACC7_STRRY

Protein

Aminoglycoside N(3')-acetyltransferase VII

Gene

aacC7

Organism
Streptomyces rimosus subsp. paromomycinus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
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    Functioni

    Resistance to paromomycin.

    Catalytic activityi

    Acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N(3')-acetyl-2-deoxystreptamine antibiotic.

    GO - Molecular functioni

    1. aminoglycoside 3-N-acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. response to antibiotic Source: UniProtKB-KW

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Antibiotic resistance

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aminoglycoside N(3')-acetyltransferase VII (EC:2.3.1.81)
    Alternative name(s):
    ACC(3)-VII
    Aminocyclitol 3-N-acetyltransferase type VII
    Gene namesi
    Name:aacC7
    OrganismiStreptomyces rimosus subsp. paromomycinus
    Taxonomic identifieri92743 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 288288Aminoglycoside N(3')-acetyltransferase VIIPRO_0000068549Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP30180.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR003679. Amioglycoside_AcTrfase.
    [Graphical view]
    PfamiPF02522. Antibiotic_NAT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P30180-1 [UniParc]FASTAAdd to Basket

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    MDELALLKRS DGPVTRTRLA RDLTALGLGD GDTVMFHTRM SAVGYVAGGP    50
    ETVIGALRDV VGERGTLMVT CGWNDAPPYD FTDWPQTWQD ARRAEHPAYD 100
    PVLSEADHNN GRLPEALRRR PGAVRSRHPD ASFAALGAAA TALTADHPWD 150
    DPHGPDSPLA RLVAMGGRVL LLGAPLEALT LLHHAEALAD APGKRFVDYE 200
    QPILVDGERV WRRFHDIDSE DGAFDYSALV PEGTEAFEII GRDMRAAGIG 250
    RRGTVGAADS HLFEARDVVD FGVAWMEEKL GRERGPGG 288
    Length:288
    Mass (Da):31,202
    Last modified:April 1, 1993 - v1
    Checksum:i430DCBBF30822382
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M22999 Genomic DNA. Translation: AAA88552.1.
    PIRiB32245.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M22999 Genomic DNA. Translation: AAA88552.1 .
    PIRi B32245.

    3D structure databases

    ProteinModelPortali P30180.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR003679. Amioglycoside_AcTrfase.
    [Graphical view ]
    Pfami PF02522. Antibiotic_NAT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and nucleotide sequencing of an aminocyclitol acetyltransferase gene from Streptomyces rimosus forma paromomycinus."
      Lopez-Cabrera M., Perez-Gonzalez J.A., Heinzel P., Piepersberg W., Jimenez A.
      J. Bacteriol. 171:321-328(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 14827 / DSM 41429 / JCM 4541 / NBRC 15454 / NRRL 2455 / VKM Ac-605.

    Entry informationi

    Entry nameiAACC7_STRRY
    AccessioniPrimary (citable) accession number: P30180
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3