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Protein

Uncharacterized oxidoreductase YbiC

Gene

ybiC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG11581-MONOMER.
ECOL316407:JW0786-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YbiC (EC:1.1.1.-)
Gene namesi
Name:ybiC
Ordered Locus Names:b0801, JW0786
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11581. ybiC.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000838401 – 361Uncharacterized oxidoreductase YbiCAdd BLAST361

Proteomic databases

PaxDbiP30178.
PRIDEiP30178.

Interactioni

Protein-protein interaction databases

BioGridi4259966. 8 interactors.
DIPiDIP-11426N.
STRINGi511145.b0801.

Structurei

Secondary structure

1361
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi5 – 7Combined sources3
Helixi9 – 23Combined sources15
Helixi27 – 43Combined sources17
Helixi46 – 48Combined sources3
Helixi50 – 52Combined sources3
Helixi53 – 61Combined sources9
Beta strandi64 – 66Combined sources3
Beta strandi72 – 77Combined sources6
Beta strandi80 – 84Combined sources5
Helixi90 – 108Combined sources19
Beta strandi109 – 119Combined sources11
Helixi124 – 133Combined sources10
Beta strandi137 – 144Combined sources8
Beta strandi165 – 171Combined sources7
Beta strandi174 – 181Combined sources8
Beta strandi183 – 186Combined sources4
Helixi188 – 197Combined sources10
Beta strandi205 – 207Combined sources3
Helixi217 – 220Combined sources4
Beta strandi222 – 224Combined sources3
Turni231 – 233Combined sources3
Helixi234 – 246Combined sources13
Turni247 – 252Combined sources6
Helixi258 – 260Combined sources3
Beta strandi269 – 277Combined sources9
Helixi279 – 281Combined sources3
Helixi287 – 299Combined sources13
Helixi314 – 326Combined sources13
Beta strandi328 – 330Combined sources3
Helixi332 – 344Combined sources13
Helixi349 – 360Combined sources12

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2G8YX-ray2.15A/B1-361[»]
ProteinModelPortaliP30178.
SMRiP30178.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP30178.

Family & Domainsi

Sequence similaritiesi

Belongs to the LDH2/MDH2 oxidoreductase family.Curated

Phylogenomic databases

eggNOGiENOG4105DG4. Bacteria.
COG2055. LUCA.
HOGENOMiHOG000173271.
InParanoidiP30178.
KOiK13574.
OMAiANGMFSI.
PhylomeDBiP30178.

Family and domain databases

InterProiIPR003767. Malate/L-lactate_DH.
[Graphical view]
PANTHERiPTHR11091. PTHR11091. 1 hit.
PfamiPF02615. Ldh_2. 1 hit.
[Graphical view]
SUPFAMiSSF89733. SSF89733. 1 hit.

Sequencei

Sequence statusi: Complete.

P30178-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESGHRFDAQ TLHSFIQAVF RQMGSEEQEA KLVADHLIAA NLAGHDSHGI
60 70 80 90 100
GMIPSYVRSW SQGHLQINHH AKTVKEAGAA VTLDGDRAFG QVAAHEAMAL
110 120 130 140 150
GIEKAHQHGI AAVALHNSHH IGRIGYWAEQ CAAAGFVSIH FVSVVGIPMV
160 170 180 190 200
APFHGRDSRF GTNPFCVVFP RKDNFPLLLD YATSAIAFGK TRVAWHKGVP
210 220 230 240 250
VPPGCLIDVN GVPTTNPAVM QESPLGSLLT FAEHKGYALA AMCEILGGAL
260 270 280 290 300
SGGKTTHQET LQTSPDAILN CMTTIIINPE LFGAPDCNAQ TEAFAEWVKA
310 320 330 340 350
SPHDDDKPIL LPGEWEVNTR RERQKQGIPL DAGSWQAICD AARQIGMPEE
360
TLQAFCQQLA S
Length:361
Mass (Da):38,897
Last modified:November 1, 1997 - v2
Checksum:i2B29784979E48543
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti23 – 24MG → IP in AAA53657 (PubMed:8037924).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02123 Genomic DNA. Translation: AAA53657.1.
U00096 Genomic DNA. Translation: AAC73888.1.
AP009048 Genomic DNA. Translation: BAA35467.1.
PIRiA64817.
RefSeqiNP_415322.1. NC_000913.3.
WP_000443530.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73888; AAC73888; b0801.
BAA35467; BAA35467; BAA35467.
GeneIDi945412.
KEGGiecj:JW0786.
eco:b0801.
PATRICi32116805. VBIEscCol129921_0828.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02123 Genomic DNA. Translation: AAA53657.1.
U00096 Genomic DNA. Translation: AAC73888.1.
AP009048 Genomic DNA. Translation: BAA35467.1.
PIRiA64817.
RefSeqiNP_415322.1. NC_000913.3.
WP_000443530.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2G8YX-ray2.15A/B1-361[»]
ProteinModelPortaliP30178.
SMRiP30178.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259966. 8 interactors.
DIPiDIP-11426N.
STRINGi511145.b0801.

Proteomic databases

PaxDbiP30178.
PRIDEiP30178.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73888; AAC73888; b0801.
BAA35467; BAA35467; BAA35467.
GeneIDi945412.
KEGGiecj:JW0786.
eco:b0801.
PATRICi32116805. VBIEscCol129921_0828.

Organism-specific databases

EchoBASEiEB1541.
EcoGeneiEG11581. ybiC.

Phylogenomic databases

eggNOGiENOG4105DG4. Bacteria.
COG2055. LUCA.
HOGENOMiHOG000173271.
InParanoidiP30178.
KOiK13574.
OMAiANGMFSI.
PhylomeDBiP30178.

Enzyme and pathway databases

BioCyciEcoCyc:EG11581-MONOMER.
ECOL316407:JW0786-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP30178.
PROiP30178.

Family and domain databases

InterProiIPR003767. Malate/L-lactate_DH.
[Graphical view]
PANTHERiPTHR11091. PTHR11091. 1 hit.
PfamiPF02615. Ldh_2. 1 hit.
[Graphical view]
SUPFAMiSSF89733. SSF89733. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYBIC_ECOLI
AccessioniPrimary (citable) accession number: P30178
Secondary accession number(s): P75778
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 118 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.