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Protein

Uncharacterized oxidoreductase YbiC

Gene

ybiC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Enzyme and pathway databases

BioCyciEcoCyc:EG11581-MONOMER.
ECOL316407:JW0786-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YbiC (EC:1.1.1.-)
Gene namesi
Name:ybiC
Ordered Locus Names:b0801, JW0786
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11581. ybiC.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Uncharacterized oxidoreductase YbiCPRO_0000083840Add
BLAST

Proteomic databases

EPDiP30178.
PaxDbiP30178.
PRIDEiP30178.

Interactioni

Protein-protein interaction databases

BioGridi4259966. 8 interactions.
DIPiDIP-11426N.
STRINGi511145.b0801.

Structurei

Secondary structure

1
361
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi5 – 73Combined sources
Helixi9 – 2315Combined sources
Helixi27 – 4317Combined sources
Helixi46 – 483Combined sources
Helixi50 – 523Combined sources
Helixi53 – 619Combined sources
Beta strandi64 – 663Combined sources
Beta strandi72 – 776Combined sources
Beta strandi80 – 845Combined sources
Helixi90 – 10819Combined sources
Beta strandi109 – 11911Combined sources
Helixi124 – 13310Combined sources
Beta strandi137 – 1448Combined sources
Beta strandi165 – 1717Combined sources
Beta strandi174 – 1818Combined sources
Beta strandi183 – 1864Combined sources
Helixi188 – 19710Combined sources
Beta strandi205 – 2073Combined sources
Helixi217 – 2204Combined sources
Beta strandi222 – 2243Combined sources
Turni231 – 2333Combined sources
Helixi234 – 24613Combined sources
Turni247 – 2526Combined sources
Helixi258 – 2603Combined sources
Beta strandi269 – 2779Combined sources
Helixi279 – 2813Combined sources
Helixi287 – 29913Combined sources
Helixi314 – 32613Combined sources
Beta strandi328 – 3303Combined sources
Helixi332 – 34413Combined sources
Helixi349 – 36012Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2G8YX-ray2.15A/B1-361[»]
ProteinModelPortaliP30178.
SMRiP30178. Positions 3-361.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP30178.

Family & Domainsi

Sequence similaritiesi

Belongs to the LDH2/MDH2 oxidoreductase family.Curated

Phylogenomic databases

eggNOGiENOG4105DG4. Bacteria.
COG2055. LUCA.
HOGENOMiHOG000173271.
InParanoidiP30178.
KOiK13574.
OMAiANGMFSI.
OrthoDBiEOG6ZPSZJ.
PhylomeDBiP30178.

Family and domain databases

InterProiIPR003767. Malate/L-lactate_DH.
[Graphical view]
PANTHERiPTHR11091. PTHR11091. 1 hit.
PfamiPF02615. Ldh_2. 1 hit.
[Graphical view]
SUPFAMiSSF89733. SSF89733. 1 hit.

Sequencei

Sequence statusi: Complete.

P30178-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESGHRFDAQ TLHSFIQAVF RQMGSEEQEA KLVADHLIAA NLAGHDSHGI
60 70 80 90 100
GMIPSYVRSW SQGHLQINHH AKTVKEAGAA VTLDGDRAFG QVAAHEAMAL
110 120 130 140 150
GIEKAHQHGI AAVALHNSHH IGRIGYWAEQ CAAAGFVSIH FVSVVGIPMV
160 170 180 190 200
APFHGRDSRF GTNPFCVVFP RKDNFPLLLD YATSAIAFGK TRVAWHKGVP
210 220 230 240 250
VPPGCLIDVN GVPTTNPAVM QESPLGSLLT FAEHKGYALA AMCEILGGAL
260 270 280 290 300
SGGKTTHQET LQTSPDAILN CMTTIIINPE LFGAPDCNAQ TEAFAEWVKA
310 320 330 340 350
SPHDDDKPIL LPGEWEVNTR RERQKQGIPL DAGSWQAICD AARQIGMPEE
360
TLQAFCQQLA S
Length:361
Mass (Da):38,897
Last modified:November 1, 1997 - v2
Checksum:i2B29784979E48543
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti23 – 242MG → IP in AAA53657 (PubMed:8037924).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02123 Genomic DNA. Translation: AAA53657.1.
U00096 Genomic DNA. Translation: AAC73888.1.
AP009048 Genomic DNA. Translation: BAA35467.1.
PIRiA64817.
RefSeqiNP_415322.1. NC_000913.3.
WP_000443530.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73888; AAC73888; b0801.
BAA35467; BAA35467; BAA35467.
GeneIDi945412.
KEGGiecj:JW0786.
eco:b0801.
PATRICi32116805. VBIEscCol129921_0828.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L02123 Genomic DNA. Translation: AAA53657.1.
U00096 Genomic DNA. Translation: AAC73888.1.
AP009048 Genomic DNA. Translation: BAA35467.1.
PIRiA64817.
RefSeqiNP_415322.1. NC_000913.3.
WP_000443530.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2G8YX-ray2.15A/B1-361[»]
ProteinModelPortaliP30178.
SMRiP30178. Positions 3-361.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259966. 8 interactions.
DIPiDIP-11426N.
STRINGi511145.b0801.

Proteomic databases

EPDiP30178.
PaxDbiP30178.
PRIDEiP30178.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73888; AAC73888; b0801.
BAA35467; BAA35467; BAA35467.
GeneIDi945412.
KEGGiecj:JW0786.
eco:b0801.
PATRICi32116805. VBIEscCol129921_0828.

Organism-specific databases

EchoBASEiEB1541.
EcoGeneiEG11581. ybiC.

Phylogenomic databases

eggNOGiENOG4105DG4. Bacteria.
COG2055. LUCA.
HOGENOMiHOG000173271.
InParanoidiP30178.
KOiK13574.
OMAiANGMFSI.
OrthoDBiEOG6ZPSZJ.
PhylomeDBiP30178.

Enzyme and pathway databases

BioCyciEcoCyc:EG11581-MONOMER.
ECOL316407:JW0786-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP30178.
PROiP30178.

Family and domain databases

InterProiIPR003767. Malate/L-lactate_DH.
[Graphical view]
PANTHERiPTHR11091. PTHR11091. 1 hit.
PfamiPF02615. Ldh_2. 1 hit.
[Graphical view]
SUPFAMiSSF89733. SSF89733. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural analysis of the rhlE gene of Escherichia coli."
    Ohmori H.
    Jpn. J. Genet. 69:1-12(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYBIC_ECOLI
AccessioniPrimary (citable) accession number: P30178
Secondary accession number(s): P75778
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: November 1, 1997
Last modified: March 16, 2016
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.