ID   YAAJ_ECOLI              Reviewed;         476 AA.
AC   P30143;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   27-MAR-2024, entry version 146.
DE   RecName: Full=Uncharacterized transporter YaaJ;
GN   Name=yaaJ; OrderedLocusNames=b0007, JW0006;
OS   Escherichia coli (strain K12).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA   Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA   Mizobuchi K., Nakata A.;
RT   "Systematic sequencing of the Escherichia coli genome: analysis of the
RT   0-2.4 min region.";
RL   Nucleic Acids Res. 20:3305-3308(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000305}.
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DR   EMBL; U00096; AAC73118.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAB96585.1; -; Genomic_DNA.
DR   PIR; G64720; G64720.
DR   RefSeq; NP_414548.1; NC_000913.3.
DR   RefSeq; WP_001112606.1; NZ_LN832404.1.
DR   AlphaFoldDB; P30143; -.
DR   SMR; P30143; -.
DR   BioGRID; 4261938; 470.
DR   STRING; 511145.b0007; -.
DR   TCDB; 2.A.25.1.10; the alanine or glycine:cation symporter (agcs) family.
DR   PaxDb; 511145-b0007; -.
DR   EnsemblBacteria; AAC73118; AAC73118; b0007.
DR   GeneID; 66671701; -.
DR   GeneID; 944745; -.
DR   KEGG; ecj:JW0006; -.
DR   KEGG; eco:b0007; -.
DR   PATRIC; fig|1411691.4.peg.2276; -.
DR   EchoBASE; EB1516; -.
DR   eggNOG; COG1115; Bacteria.
DR   HOGENOM; CLU_024867_0_1_6; -.
DR   InParanoid; P30143; -.
DR   OMA; TGNMTQS; -.
DR   OrthoDB; 9806926at2; -.
DR   PhylomeDB; P30143; -.
DR   BioCyc; EcoCyc:YAAJ-MONOMER; -.
DR   PRO; PR:P30143; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..476
FT                   /note="Uncharacterized transporter YaaJ"
FT                   /id="PRO_0000161566"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        391..411
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   476 AA;  51663 MW;  2F6EB2E12E126E63 CRC64;
     MPDFFSFINS VLWGSVMIYL LFGAGCWFTF RTGFVQFRYI RQFGKSLKNS IHPQPGGLTS
     FQSLCTSLAA RVGSGNLAGV ALAITAGGPG AVFWMWVAAF IGMATSFAEC SLAQLYKERD
     VNGQFRGGPA WYMARGLGMR WMGVLFAVFL LIAYGIIFSG VQANAVARAL SFSFDFPPLV
     TGIILAVFTL LAITRGLHGV ARLMQGFVPL MAIIWVLTSL VICVMNIGQL PHVIWSIFES
     AFGWQEAAGG AAGYTLSQAI TNGFQRSMFS NEAGMGSTPN AAAAAASWPP HPAAQGIVQM
     IGIFIDTLVI CTASAMLILL AGNGTTYMPL EGIQLIQKAM RVLMGSWGAE FVTLVVILFA
     FSSIVANYIY AENNLFFLRL NNPKAIWCLR ICTFATVIGG TLLSLPLMWQ LADIIMACMA
     ITNLTAILLL SPVVHTIASD YLRQRKLGVR PVFDPLRYPD IGRQLSPDAW DDVSQE
//