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P30143 (YAAJ_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized transporter YaaJ
Gene names
Name:yaaJ
Ordered Locus Names:b0007, JW0006
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length476 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Cell inner membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the sodium:alanine (SAF) symporter family.

Ontologies

Keywords
   Biological processSymport
Transport
   Cellular componentCell inner membrane
Cell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionalanine:sodium symporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 476476Uncharacterized transporter YaaJ
PRO_0000161566

Regions

Transmembrane4 – 2421Helical; Potential
Transmembrane81 – 10121Helical; Potential
Transmembrane141 – 16121Helical; Potential
Transmembrane174 – 19421Helical; Potential
Transmembrane207 – 22721Helical; Potential
Transmembrane233 – 25321Helical; Potential
Transmembrane300 – 32021Helical; Potential
Transmembrane351 – 37121Helical; Potential
Transmembrane391 – 41121Helical; Potential
Transmembrane414 – 43421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P30143 [UniParc].

Last modified July 1, 1993. Version 1.
Checksum: 2F6EB2E12E126E63

FASTA47651,663
        10         20         30         40         50         60 
MPDFFSFINS VLWGSVMIYL LFGAGCWFTF RTGFVQFRYI RQFGKSLKNS IHPQPGGLTS 

        70         80         90        100        110        120 
FQSLCTSLAA RVGSGNLAGV ALAITAGGPG AVFWMWVAAF IGMATSFAEC SLAQLYKERD 

       130        140        150        160        170        180 
VNGQFRGGPA WYMARGLGMR WMGVLFAVFL LIAYGIIFSG VQANAVARAL SFSFDFPPLV 

       190        200        210        220        230        240 
TGIILAVFTL LAITRGLHGV ARLMQGFVPL MAIIWVLTSL VICVMNIGQL PHVIWSIFES 

       250        260        270        280        290        300 
AFGWQEAAGG AAGYTLSQAI TNGFQRSMFS NEAGMGSTPN AAAAAASWPP HPAAQGIVQM 

       310        320        330        340        350        360 
IGIFIDTLVI CTASAMLILL AGNGTTYMPL EGIQLIQKAM RVLMGSWGAE FVTLVVILFA 

       370        380        390        400        410        420 
FSSIVANYIY AENNLFFLRL NNPKAIWCLR ICTFATVIGG TLLSLPLMWQ LADIIMACMA 

       430        440        450        460        470 
ITNLTAILLL SPVVHTIASD YLRQRKLGVR PVFDPLRYPD IGRQLSPDAW DDVSQE 

« Hide

References

[1]"Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region."
Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K., Mizobuchi K., Nakata A.
Nucleic Acids Res. 20:3305-3308(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00096 Genomic DNA. Translation: AAC73118.1.
AP009048 Genomic DNA. Translation: BAB96585.1.
PIRG64720.
RefSeqNP_414548.1. NC_000913.3.
YP_488313.1. NC_007779.1.

3D structure databases

ProteinModelPortalP30143.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING511145.b0007.

Proteomic databases

PRIDEP30143.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC73118; AAC73118; b0007.
BAB96585; BAB96585; BAB96585.
GeneID12932944.
944745.
KEGGecj:Y75_p0007.
eco:b0007.
PATRIC32115109. VBIEscCol129921_0006.

Organism-specific databases

EchoBASEEB1516.
EcoGeneEG11555. yaaJ.

Phylogenomic databases

eggNOGCOG1115.
HOGENOMHOG000255107.
KOK03310.
OMAFISEILW.
OrthoDBEOG6D2KVD.
PhylomeDBP30143.

Enzyme and pathway databases

BioCycEcoCyc:YAAJ-MONOMER.
ECOL316407:JW0006-MONOMER.

Gene expression databases

GenevestigatorP30143.

Family and domain databases

InterProIPR001463. Na/Ala_symport.
[Graphical view]
PfamPF01235. Na_Ala_symp. 1 hit.
[Graphical view]
PRINTSPR00175. NAALASMPORT.
TIGRFAMsTIGR00835. agcS. 1 hit.
PROSITEPS00873. NA_ALANINE_SYMP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP30143.

Entry information

Entry nameYAAJ_ECOLI
AccessionPrimary (citable) accession number: P30143
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: July 1, 1993
Last modified: May 14, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene