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Protein

Glutathione S-transferase 2

Gene

GSTA2

Organism
Triticum aestivum (Wheat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BRENDAi2.5.1.18. 6500.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase 2 (EC:2.5.1.18)
Alternative name(s):
GST class-phi
Gene namesi
Name:GSTA2
OrganismiTriticum aestivum (Wheat)
Taxonomic identifieri4565 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeTriticinaeTriticum
Proteomesi
  • UP000019116 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001858591 – 291Glutathione S-transferase 2Add BLAST291

Structurei

3D structure databases

ProteinModelPortaliP30111.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 83GST N-terminalAdd BLAST82
Domaini93 – 223GST C-terminalAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni41 – 42Glutathione bindingBy similarity2
Regioni54 – 55Glutathione bindingBy similarity2
Regioni67 – 68Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated
Contains 1 GST C-terminal domain.Curated
Contains 1 GST N-terminal domain.Curated

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P30111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPVKVFGHP MLTNVARVLL FLEEVGAEYE LVPVDFVAGE HKRPQHVQLN
60 70 80 90 100
PFAKMPGFQD GESLHIKSRA IAKYILRKYG GTAGLDLLGE NSGIEELAMV
110 120 130 140 150
DVWTEVEAQQ YYPAISPVVF ECIIIPFIIP GGGAAPNQTV VDESLERLRG
160 170 180 190 200
VLGIYEARLE KSRYLAGDSI SFADLNHIPF TFYFMTTPYA KVFDEYPKVK
210 220 230 240 250
AWWEMLMARP AVQRVCKHMP TEFKLRARTR CLCTPRGCVP CRAGDDPTQE
260 270 280 290
KRPPSRGWVI ICPSTSSIPF QFQQHEESAC ASARASPDSL L
Length:291
Mass (Da):32,580
Last modified:April 1, 1993 - v1
Checksum:iD0EB6F13D8F85909
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56004 Genomic DNA. Translation: CAA39480.1.
PIRiT06510.

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.
GrameneiTRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56004 Genomic DNA. Translation: CAA39480.1.
PIRiT06510.

3D structure databases

ProteinModelPortaliP30111.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiTRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.
GrameneiTRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.2; TRIAE_CS42_4BS_TGACv1_327885_AA1077750.

Enzyme and pathway databases

BRENDAi2.5.1.18. 6500.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGSTF2_WHEAT
AccessioniPrimary (citable) accession number: P30111
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: November 30, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

GSTA2 is said to be a defective gene.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.