P30111 (GSTF2_WHEAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutathione S-transferase 2
EC=2.5.1.18

Alternative name(s):
GST class-phi

Gene names

Name:

GSTA2

Organism

Triticum aestivum (Wheat)

Taxonomic identifier

4565 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Pooideae › Triticeae › Triticum

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Miscellaneous	GSTA2 is said to be a defective gene.
Sequence similarities	Belongs to the GST superfamily. Phi family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Molecular function	Transferase
Gene Ontology (GO)
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Glutathione S-transferase 2		PRO_0000185859
Regions
	Domain	2 – 83	82	GST N-terminal
	Domain	93 – 223	131	GST C-terminal
	Region	41 – 42	2	Glutathione binding By similarity
	Region	54 – 55	2	Glutathione binding By similarity
	Region	67 – 68	2	Glutathione binding By similarity

Sequences

	Sequence		Length	Mass (Da)
	P30111 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: D0EB6F13D8F85909	FASTA	291	32,580
	10 20 30 40 50 60 MSPVKVFGHP MLTNVARVLL FLEEVGAEYE LVPVDFVAGE HKRPQHVQLN PFAKMPGFQD 70 80 90 100 110 120 GESLHIKSRA IAKYILRKYG GTAGLDLLGE NSGIEELAMV DVWTEVEAQQ YYPAISPVVF 130 140 150 160 170 180 ECIIIPFIIP GGGAAPNQTV VDESLERLRG VLGIYEARLE KSRYLAGDSI SFADLNHIPF 190 200 210 220 230 240 TFYFMTTPYA KVFDEYPKVK AWWEMLMARP AVQRVCKHMP TEFKLRARTR CLCTPRGCVP 250 260 270 280 290 CRAGDDPTQE KRPPSRGWVI ICPSTSSIPF QFQQHEESAC ASARASPDSL L

References

[1]	"A wheat glutathione-S-transferase gene with transposon-like sequences in the promoter region." Mauch F., Hertig C., Rebmann G., Bull J., Dudler R. Plant Mol. Biol. 16:1089-1091(1991) [PubMed: 1650615] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: cv. Cheyenne.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X56004 Genomic DNA. Translation: CAA39480.1.
PIR	T06510.
3D structure databases
ProteinModelPortal	P30111.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
Gramene	P30111.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSTF2_WHEAT

Accession

Primary (citable) accession number: P30111

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	September 21, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program