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P30110

- GSTF1_WHEAT

UniProt

P30110 - GSTF1_WHEAT

Protein

Glutathione S-transferase 1

Gene

GSTA1

Organism
Triticum aestivum (Wheat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
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    • Comment

    Functioni

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase 1 (EC:2.5.1.18)
    Alternative name(s):
    GST class-phi
    Gene namesi
    Name:GSTA1
    OrganismiTriticum aestivum (Wheat)
    Taxonomic identifieri4565 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum
    ProteomesiUP000019116: Unplaced

    Organism-specific databases

    GrameneiP30110.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 229229Glutathione S-transferase 1PRO_0000185858Add
    BLAST

    Expressioni

    Inductioni

    By pathogen infection.

    Structurei

    3D structure databases

    ProteinModelPortaliP30110.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini2 – 8382GST N-terminalAdd
    BLAST
    Domaini93 – 223131GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni41 – 422Glutathione bindingBy similarity
    Regioni54 – 552Glutathione bindingBy similarity
    Regioni67 – 682Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily. Phi family.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P30110-1 [UniParc]FASTAAdd to Basket

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    MSPVKVFGHP MLTNVARVLL FLEEVGAEYE LVPMDFVAGE HKRPQHVQLN    50
    PFAKMPGFQD GDLVLFESRA IAKYILRKYG GTAGLDLLGE NSGIEELAMV 100
    DVWTEVEAQQ YYPAISPVVF ECIIIPFIIP GGGAAPNQTV VDESLERLRG 150
    VLGIYEARLE KSRYLAGDSI TFADLNHIPF TFYFMTTPYA KVFDDYPKVK 200
    AWWEMLMARP AVQRVCKHMP TEFKLGAQY 229
    Length:229
    Mass (Da):25,828
    Last modified:April 1, 1993 - v1
    Checksum:iC6A2543D53678570
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti34 – 341M → V.
    Natural varianti171 – 1711T → S in strain: cv. Fidel.
    Natural varianti195 – 1951D → E in strain: cv. Fidel.
    Natural varianti226 – 2261G → R in strain: cv. Fidel.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X56012 Genomic DNA. Translation: CAA39487.1.
    PIRiT06509.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X56012 Genomic DNA. Translation: CAA39487.1 .
    PIRi T06509.

    3D structure databases

    ProteinModelPortali P30110.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    Gramenei P30110.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A pathogen-induced wheat gene encodes a protein homologous to glutathione-S-transferases."
      Dudler R., Hertig C., Rebmann G., Bull J., Mauch F.
      Mol. Plant Microbe Interact. 4:14-18(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Cheyenne.

    Entry informationi

    Entry nameiGSTF1_WHEAT
    AccessioniPrimary (citable) accession number: P30110
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3