Reviewed, UniProtKB/Swiss-Prot P30109 (GSTF1_TOBAC)

Names and origin

Protein names

Recommended name:
    Glutathione S-transferase PARB
    EC=2.5.1.18
Alternative name(s):
    GST class-phi

Gene names

Name:

PARB

Organism

Nicotiana tabacum (Common tobacco)

Taxonomic identifier

4097 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Nicotianoideae › Nicotianeae › Nicotiana

Protein attributes

Sequence length	213 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
Catalytic activity	RX + glutathione = HX + R-S-glutathione.
Developmental stage	Its expression was observed during transition from G0 to the S phase of tobacco mesophyll protoplasts in vitro.
Induction	By auxin.
Sequence similarities	Belongs to the GST superfamily. Phi family. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Molecular function	Transferase
Gene Ontology (GO)
Molecular function	glutathione transferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 213	213	Glutathione S-transferase PARB		PRO_0000185856
Regions
	Domain	1 – 82	82	GST N-terminal
	Domain	89 – 213	125	GST C-terminal

Sequences

	Sequence		Length	Mass (Da)
	P30109-1 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: 0AB971171E7CCFDC	FASTA	213	23,967
	10 20 30 40 50 60 MAIKVHGSPM STATMRVAAC LIEKELDFEF VPVDMASGEH KKHPYLSLNP FGQVPAFEDG 70 80 90 100 110 120 DLKLFESRAI TQYIAHVYAD NGYQLILQDP KKMPSMSVWM EVEGQKFEPP ATKLTWELGI 130 140 150 160 170 180 KPIIGMTTDD AAVKESEAQL SKVLDIYETQ LAESKYLGGD SFTLVDLHHI PNIYYLMSSK 190 200 210 VKEVFDSRPR VSAWCADILA RPAWVKGLEK LQK

References

[1]	"parB: an auxin-regulated gene encoding glutathione S-transferase." Takahashi Y., Nagata T. Proc. Natl. Acad. Sci. U.S.A. 89:56-59(1992) [PubMed: 1729717] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Xanthi NC. Tissue: Leaf mesophyll.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D10524 mRNA. Translation: BAA01394.1.
PIR	A41789.
3D structure databases
HSSP	HSSP built from PDB template 1GNW based on UniProtKB P46422.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.5.1.18. 298.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012335. Thioredoxin_fold. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
Pfam	PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
PROSITE	PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GSTF1_TOBAC

Accession

Primary (citable) accession number: P30109

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	May 5, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)