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Protein

Glutathione S-transferase Y-2

Gene

GSTY2

Organism
Pichia kudriavzevii (Yeast) (Issatchenkia orientalis)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

Keywordsi

Molecular functionTransferase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase Y-2 (EC:2.5.1.18)
Gene namesi
Name:GSTY2
OrganismiPichia kudriavzevii (Yeast) (Issatchenkia orientalis)
Taxonomic identifieri4909 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPichiaceaePichia

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001859832 – 191Glutathione S-transferase Y-2Add BLAST190

Expressioni

Inductioni

By O-dinitrobenzene.

Structurei

3D structure databases

ProteinModelPortaliP30102
SMRiP30102
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 80GST N-terminalAdd BLAST79
Domaini85 – 191GST C-terminalAdd BLAST107

Sequence similaritiesi

Belongs to the GST superfamily.Curated

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P30102-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFATVYIKP HTPRGDWLAS LGQYVGLEIK TVDYKSAEAS KFEELFPLKR
60 70 80 90 100
VPALVTPNGF QLTELIAIVE YIVAKGSKPE LSGKTTEERA TNTRWLSFFN
110 120 130 140 150
SDFVQAAGGY FMGPNDEIKQ QSLQTMLSLL EYIDKHLSQS KYFTNNTILT
160 170 180 190
ADIFAFQIFA MAKQFGVDFT HYPNVERFTG EVSQHPIIKN M
Length:191
Mass (Da):21,652
Last modified:January 23, 2007 - v2
Checksum:i3BD1849C2C91363D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57957 mRNA Translation: CAA41025.1
PIRiS16178

Similar proteinsi

Entry informationi

Entry nameiGSTY2_PICKU
AccessioniPrimary (citable) accession number: P30102
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 72 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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