Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P30102 (GSTY2_ISSOR) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase Y-2

EC=2.5.1.18
Gene names
Name:GSTY2
OrganismIssatchenkia orientalis (Yeast) (Candida krusei)
Taxonomic identifier4909 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesPichiaceaePichia

Protein attributes

Sequence length191 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Induction

By O-dinitrobenzene.

Sequence similarities

Belongs to the GST superfamily.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.2
Chain2 – 191190Glutathione S-transferase Y-2
PRO_0000185983

Regions

Domain2 – 8079GST N-terminal
Domain85 – 191107GST C-terminal

Sequences

Sequence LengthMass (Da)Tools
P30102 [UniParc].

Last modified January 23, 2007. Version 2.
Checksum: 3BD1849C2C91363D

FASTA19121,652
        10         20         30         40         50         60 
MTFATVYIKP HTPRGDWLAS LGQYVGLEIK TVDYKSAEAS KFEELFPLKR VPALVTPNGF 

        70         80         90        100        110        120 
QLTELIAIVE YIVAKGSKPE LSGKTTEERA TNTRWLSFFN SDFVQAAGGY FMGPNDEIKQ 

       130        140        150        160        170        180 
QSLQTMLSLL EYIDKHLSQS KYFTNNTILT ADIFAFQIFA MAKQFGVDFT HYPNVERFTG 

       190 
EVSQHPIIKN M 

« Hide

References

[1]"Nucleotide sequence of the yeast glutathione S-transferase cDNA."
Tamaki H., Kumagai H., Tochikura T.
Biochim. Biophys. Acta 1089:276-279(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Glutathione S-transferase in yeast: induction of mRNA, cDNA cloning and expression in Escherichia coli."
Tamaki H., Kumagai H., Tochikura T.
Biochem. Biophys. Res. Commun. 172:669-675(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-16 AND 164-189.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X57957 mRNA. Translation: CAA41025.1.
PIRS16178.

3D structure databases

ProteinModelPortalP30102.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTY2_ISSOR
AccessionPrimary (citable) accession number: P30102
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 64 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families