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Protein

Chalcone synthase 6

Gene

CHS6

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi: flavonoid biosynthesis

This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.
View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei164PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processFlavonoid biosynthesis

Enzyme and pathway databases

BRENDAi2.3.1.74 2483
UniPathwayiUPA00154

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 6 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 6
Gene namesi
Name:CHS6
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
Proteomesi
  • UP000008827 Componenti: Chromosome 9

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002160661 – 388Chalcone synthase 6Add BLAST388

Proteomic databases

PRIDEiP30080

Expressioni

Gene expression databases

GenevisibleiP30080 GM

Interactioni

Protein-protein interaction databases

STRINGi3847.GLYMA09G08780.1

Structurei

3D structure databases

ProteinModelPortaliP30080
SMRiP30080
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Phylogenomic databases

eggNOGiENOG410IKG2 Eukaryota
COG3424 LUCA
InParanoidiP30080
KOiK00660
OMAiSVCAYME

Family and domain databases

Gene3Di3.40.47.10, 2 hits
InterProiView protein in InterPro
IPR012328 Chalcone/stilbene_synth_C
IPR018088 Chalcone/stilbene_synthase_AS
IPR001099 Chalcone/stilbene_synthase_N
IPR011141 Polyketide_synthase_type-III
IPR016039 Thiolase-like
PANTHERiPTHR11877 PTHR11877, 1 hit
PfamiView protein in Pfam
PF02797 Chal_sti_synt_C, 1 hit
PF00195 Chal_sti_synt_N, 1 hit
PIRSFiPIRSF000451 PKS_III, 1 hit
SUPFAMiSSF53901 SSF53901, 2 hits
PROSITEiView protein in PROSITE
PS00441 CHALCONE_SYNTH, 1 hit

Sequencei

Sequence statusi: Complete.

P30080-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSVEEIRKA QRAEGPATVM AIGTATPPNC VDQSTYPDYY FRITNSDHMN
60 70 80 90 100
ELKEKFKRMC DKSMIKKRYM YLNEEILKEN PSVCAYMEPS LDARQDMVVV
110 120 130 140 150
EVPKLGKEAA TKAIKEWGQP KSKITHLIFC TTSGVDMPGA DYQLTKLLGL
160 170 180 190 200
RPSVKRYMMY QQGCFAGGTV LRLAKDLAEN NTGARVLVVC SEITAVTFRG
210 220 230 240 250
PSDTHLDSLV GQALFGDGAA AVIVGSDPLP AEKPLFELVW TAQTILPDSE
260 270 280 290 300
GAIDGHLREV GLTFHLLKDV PGLISKNIQK ALVEAFQPLG IDDYNSIFWI
310 320 330 340 350
AHPGGPAILD QVEAKLGLKP EKMEATRHVL SEYGNMSSAC VLFILDQMRK
360 370 380
KSIENGLGTT GEGLEWGVLF GFGPGLTVET VVLRSVTV
Length:388
Mass (Da):42,532
Last modified:April 1, 1993 - v1
Checksum:i77062AE778734BAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L03352 Genomic DNA Translation: AAA33951.1
PIRiJQ2259
RefSeqiXP_003533807.1, XM_003533759.3

Genome annotation databases

EnsemblPlantsiKRH37579; KRH37579; GLYMA_09G075200
GeneIDi100809433
GrameneiKRH37579; KRH37579; GLYMA_09G075200
KEGGigmx:100809433

Similar proteinsi

Entry informationi

Entry nameiCHS6_SOYBN
AccessioniPrimary (citable) accession number: P30080
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: April 25, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health