P30040C9J183Q3MJC3Q6FHT4ERP29_HUMANEndoplasmic reticulum resident protein 29ERp29Endoplasmic reticulum resident protein 28ERp28Endoplasmic reticulum resident protein 31ERp31ERP29C12orf8ERP28Homo sapiensHumanEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomoERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif.NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)CHARACTERIZATIONThe WashU-Merck EST project.NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201).NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)The finished DNA sequence of human chromosome 12.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)Human liver protein map: update 1993.PROTEIN SEQUENCE OF 33-52Human liver protein map: a reference database established by microsequencing and gel comparison.PRELIMINARY PROTEIN SEQUENCE OF 33-42PROTEIN SEQUENCE OF 113-122IDENTIFICATION BY MASS SPECTROMETRYPARTIAL PROTEIN SEQUENCEHuman ERp29: isolation, primary structural characterisation and two-dimensional gel mapping.PARTIAL PROTEIN SEQUENCECHARACTERIZATIONA subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins.COMPONENT OF A CHAPERONE COMPLEXProteomic analysis of early melanosomes: identification of novel melanosomal proteins.SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Initial characterization of the human central proteome.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]A secreted tyrosine kinase acts in the extracellular environment.PHOSPHORYLATION AT TYR-64 AND TYR-66An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]N-terminome analysis of the human mitochondrial proteome.CLEAVAGE OF SIGNAL PEPTIDE [LARGE SCALE ANALYSIS] AFTER GLY-32IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER.Homodimer. Part of a large chaperone multiprotein complex comprising CABP1, DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PPIB, SDF2L1, UGGT1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX (PubMed:12475965).P30040Q15848false3P30040O95393false3P30040Q6ICB0false3P30040Q9P0W2false6P30040Q8IXM6false3P30040O43765false3P30040Q96EQ0false6P30040Q969S0false3P30040Q9NVC3false3P30040P55061false3P30040Q8N661false3P30040Q5TGU0false3P30040Q5BVD1false3P30040Q9UMX0false3P30040Q9UHD9false3PRO_0000021197P52555true2Endoplasmic reticulum lumenMelanosomeIdentified by mass spectrometry in melanosome fractions from stage I to stage IV.P30040-11P30040-22Ubiquitous. Mostly expressed in secretory tissues.3D-structureAlternative splicingDirect protein sequencingEndoplasmic reticulumPhosphoproteinReference proteomeSignalVIPKSIMVTSMAAAVPRAAFLSPLLPLLLGFLLLSAPHGGSGLHTKGALPLDTVTFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKESYPVFYLFRDGDFENPVPYTGAVKVGAIQRWLKGQGVYLGMPGCLPVYDALAGEFIRASGVEARQALLKQGQDNLSSVKETQKKWAEQYLKIMGKILDQGEDFPASEMTRIARLIEKNKMSDGKKEELQKSLNILTAFQKKGAEKEEL
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