Reviewed, UniProtKB/Swiss-Prot P29968 (XOXF_PARDE)

Names and origin

Protein names

Recommended name:
    Putative dehydrogenase xoxF
    EC=1.1.99.-

Gene names

Name:

xoxF

Organism

Paracoccus denitrificans

Taxonomic identifier

266 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	600 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Cofactor	Binds 1 PQQ group per subunit By similarity. Binds 1 calcium ion per subunit By similarity.
Sequence similarities	Belongs to the bacterial PQQ dehydrogenase family.

Ontologies

Keywords
Domain	Signal
Ligand	Calcium Metal-binding
Molecular function	Oxidoreductase
PTM	PQQ
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	membrane Inferred from electronic annotation. Source: InterPro outer membrane-bounded periplasmic space Inferred from electronic annotation. Source: InterPro
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on CH-OH group of donors Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 21	21	Potential
	Chain	22 – 600	579	Putative dehydrogenase xoxF		PRO_0000025564
Sites
	Active site	318	1	Proton acceptor Potential
	Metal binding	192	1	Calcium By similarity
	Metal binding	276	1	Calcium By similarity

Sequences

	Sequence		Length	Mass (Da)
	P29968-1 [UniParc]. Last modified October 1, 1996. Version 2. Checksum: DCA996F1BCC5A3CE	FASTA	600	65,159
	10 20 30 40 50 60 MKNLMNGACL ALLMSGTAAL ANEQRAGRDR QAPQWAIQMG DYANTRYSTL DQINKDNVKD 70 80 90 100 110 120 LRVAWTFSTG VLRGHEGSPL VIGDVMYVHT PFPNRVFALD LNDNGKILWR YEPQQDPNVI 130 140 150 160 170 180 AVMSCDTVYR GLSYADGMIL LGQADTTVVA LDATSGEVKW STKIGDPGIG ETLTATVVPV 190 200 210 220 230 240 KDKVLVGISG GEYGVRGRMT ALNLTDGSEA WKAWSTGPDE ELLVDPETTT HLGKPIGADS 250 260 270 280 290 300 SLNSWEGDQW QIGGGTIWGW FSYDPDLNLV YYGTGNPSTW NPSQRPGDNK WSMTIMARDA 310 320 330 340 350 360 DTGMAKWFYQ MTPHDEWDYD GVNEMILTNQ TVDGQERKLL THFDRNGLAY TMDRETGELL 370 380 390 400 410 420 VAEKYDPVVN WTTGVDMDPN SETYGRPAVV AEYSTAQNGE DENTTGVCPA ALGTKDQQPA 430 440 450 460 470 480 AFSPKTNLFY VPTNHVCMDY EPFRVAYTAG QPYVGATLSM YPAPNSHGGM GNFIAWHNTT 490 500 510 520 530 540 GEIKWSVPEQ FSVWSGALAT AGDVVFYGTL EGYLKPVDAQ TGEELYKFKT PSGIIGNVMT 550 560 570 580 590 600 YEHGGKQYVG ILSGVGGWAG IGLAAGLTNP NDGLGAVGGY ASLSQYTELG GQLTVFELPG

References

[1]	Harms N. Submitted (AUG-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Isolation, sequencing, and mutagenesis of the gene encoding cytochrome c553i of Paracoccus denitrificans and characterization of the mutant strain." Ras J., Reijnders W.N.M., van Spanning R.J.M., Harms N., Oltmann L.F., Stouthamer A.H. J. Bacteriol. 173:6971-6979(1991) [PubMed: 1657873] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 380-600. Strain: Pd 1235.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U34346 Genomic DNA. Translation: AAC44555.1. M75583 Genomic DNA. Translation: AAA25574.1.
PIR	A41378.
3D structure databases
HSSP	HSSP built from PDB template 1H4J based on UniProtKB P16027.
ModBase	Search...
Family and domain databases
InterPro	IPR019556. PQQ-dependent_C. IPR019551. PQQ-dependent_N. IPR018391. PQQ_beta_propeller_repeat. IPR017512. PQQ_MeOH/EtOH_DH. IPR002372. PQQ_repeat. IPR011047. Quino_AlcDH-like. IPR001479. Quinoprotein_DH_CS. [Graphical view]
Gene3D	G3DSA:2.140.10.10. Quinoprotein_alc_DH-like. 1 hit.
Pfam	PF01011. PQQ. 4 hits. PF10535. PQQ_C. 1 hit. PF10527. PQQ_N. 1 hit. [Graphical view]
SMART	SM00564. PQQ. 5 hits. [Graphical view]
TIGRFAMs	TIGR03075. PQQ_enz_alc_DH. 1 hit.
PROSITE	PS00364. BACTERIAL_PQQ_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XOXF_PARDE

Accession

Primary (citable) accession number: P29968

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	October 1, 1996
Last modified:	June 16, 2009
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)