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P29954 (MANA_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannose-6-phosphate isomerase

EC=5.3.1.8
Alternative name(s):
Phosphohexomutase
Phosphomannose isomerase
Short name=PMI
Gene names
Name:pmi
Ordered Locus Names:R02982
ORF Names:SMc03111
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannose 6-phosphate = D-fructose 6-phosphate.

Sequence similarities

Belongs to the N-acylglucosamine 2-epimerase family.

Caution

It is uncertain whether Met-1 or Met-3 is the initiator.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionmannose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 387387Mannose-6-phosphate isomerase
PRO_0000208953

Sequences

Sequence LengthMass (Da)Tools
P29954 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: 334893FF7F9B3E95

FASTA38743,489
        10         20         30         40         50         60 
MGMDIHLQAG ELAGWLNDAA LPLWRQKGFD GEGGGFVETI DMKGEPTRDD RRSRVQPRQV 

        70         80         90        100        110        120 
YCFAAAGRRG WDGDWRTAAE GGLLYFDRVY GQPGGFYGAL ANADGKLIDA SFDLYNQAFA 

       130        140        150        160        170        180 
LLAFAHLAEV LPERGAEMVG RSDKLRRQLE ARCKHPLAGF EEDDPPRLPL GSNPHMHLFE 

       190        200        210        220        230        240 
ACLASEEVEG FDRVAWANLA DEIAHLAMDR FIDAESGALR EFFDHDWAPF PGEKGRIVEP 

       250        260        270        280        290        300 
GHLFEWAWLL LRWAERRGNA QAIVKARRLF EIGEKDGTCP DRDVVVMTLF DDFSVADPTA 

       310        320        330        340        350        360 
RLWPQTEWLK AAIRFAALTE GAERERYLAS AGRAAAALQR FLNVPVRGLW RDKQKADGSF 

       370        380 
VEEPAPASTF YHILCAIYEL EDCLKRM 

« Hide

References

« Hide 'large scale' references
[1]"The Rhizobium meliloti pmi gene encodes a new type of phosphomannose isomerase."
Schmidt M., Arnold W., Niemann A., Kleickmann A., Puehler A.
Gene 122:35-43(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: RCR2011 / SU47.
[2]"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021."
Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. expand/collapse author list , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.
Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1021.
[3]"The composite genome of the legume symbiont Sinorhizobium meliloti."
Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. expand/collapse author list , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J.
Science 293:668-672(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1021.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M96584 Genomic DNA. Translation: AAA26356.1.
AL591688 Genomic DNA. Translation: CAC47561.1.
RefSeqNP_387088.1. NC_003047.1.

3D structure databases

ProteinModelPortalP29954.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SMc03111.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC47561; CAC47561; SMc03111.
GeneID1234665.
KEGGsme:SMc03111.
PATRIC23635568. VBISinMel96828_4508.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2942.
HOGENOMHOG000278099.
KOK01809.
OMAPQTERIK.
OrthoDBEOG6DC6G1.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-3057-MONOMER.

Family and domain databases

Gene3D1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
[Graphical view]
SUPFAMSSF48208. SSF48208. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMANA_RHIME
AccessionPrimary (citable) accession number: P29954
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: May 14, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families