P29899 (CYCL_PARDE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c-L

Alternative name(s):
Cytochrome c551I
Cytochrome c552

Gene names

Name:

moxG

Organism

Paracoccus denitrificans

Taxonomic identifier

266 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	177 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Electron acceptor for MDH. Acts in methanol oxidation.
Subcellular location	Periplasm Potential.
Induction	During growth on methanol.
Post-translational modification	Binds 1 heme group per subunit.
Biophysicochemical properties	Redox potential: E0 is about +190 mV.

Ontologies

Keywords
Biological process	Electron transport Methanol utilization Transport
Cellular component	Periplasm
Domain	Signal
Ligand	Heme Iron Metal-binding
Technical term	3D-structure
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW methanol metabolic process Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro heme binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

1 – 22

22

Potential

Chain

23 – 177

155

Cytochrome c-L

PRO_0000006553

Sites

Metal binding

83

1

Iron (heme axial ligand)

Binding site

79

1

Heme (covalent)

Binding site

82

1

Heme (covalent)

Secondary structure

1

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177

Helix Strand Turn

Details...

Turn

29 – 31

3

Helix

37 – 39

3

Beta strand

45 – 47

3

Helix

48 – 56

9

Turn

60 – 63

4

Turn

65 – 67

3

Helix

68 – 78

11

Helix

80 – 83

4

Beta strand

90 – 92

3

Beta strand

96 – 98

3

Helix

103 – 106

4

Helix

108 – 117

10

Turn

127 – 129

3

Helix

132 – 144

13

Helix

150 – 152

3

Helix

158 – 162

5

Sequences

	Sequence		Length	Mass (Da)
	P29899 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: 6949FBDC8B2C056E	FASTA	177	19,396
	10 20 30 40 50 60 MTKPRILAAF AMTLIIPVAA MAAPQFFNII DGSPLNFDDA MEEGRDTEAV KHFLETGENV 70 80 90 100 110 120 YNEDPEILPE AEELYAGMCS GCHGHYAEGK IGPGLNDAYW TYPGNETDVG LFSTLYGGAT 130 140 150 160 170 GQMGPMWGSL TLDEMLRTMA WVRHLYTGDP KDASWLTDEQ KAGFTPFQPK SSGEDQS

References

[1]	"Isolation and characterization of the moxJ, moxG, moxI, and moxR genes of Paracoccus denitrificans: inactivation of moxJ, moxG, and moxR and the resultant effect on methylotrophic growth." van Spanning R.J.M., Wansell C.W., de Boer T., Hazelaar M.J., Anazawa H., Harms N., Oltmann L.F., Stouthamer A.H. J. Bacteriol. 173:6948-6961(1991) [PubMed: 1657871] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Pd 1222.
[2]	"Structure of an electron transfer complex: methylamine dehydrogenase, amicyanin, and cytochrome c551i." Chen L., Durley R., Mathews F.S., Davidson V.L. Science 264:86-90(1994) [PubMed: 8140419] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS).
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M57684 Genomic DNA. Translation: AAA25583.1.

PIR

B41377.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1MG2	X-ray	2.25	D/H/L/P	23-177	[»]
1MG3	X-ray	2.40	D/H/L/P	23-177	[»]
2GC4	X-ray	1.90	D/H/L/P	23-169	[»]
2GC7	X-ray	1.90	D/H/L/P	23-169	[»]
2MTA	X-ray	2.40	C	23-169	[»]

ProteinModelPortal

P29899.

SMR

P29899. Positions 23-169.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR009056. Cyt_c_dom.
IPR003088. Cyt_c_I.
IPR009153. Cyt_cL.
[Graphical view]

Gene3D

G3DSA:1.10.760.10. Cytochrome_c_R. 1 hit.

Pfam

PF00034. Cytochrom_C. 1 hit.
[Graphical view]

PIRSF

PIRSF000008. Cytochrome_c551i. 1 hit.

SUPFAM

SSF46626. Cytochrome_c. 1 hit.

TIGRFAMs

TIGR03872. Cytochrome_MoxG. 1 hit.

PROSITE

PS51007. CYTC. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

CYCL_PARDE

Accession

Primary (citable) accession number: P29899

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	November 30, 2010
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program