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Protein

Aminoglycoside N(3)-acetyltransferase IX

Gene

aacC9

Organism
Micromonospora chalcea
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Resistance to neomycin.

Catalytic activityi

Acetyl-CoA + a 2-deoxystreptamine antibiotic = CoA + N3-acetyl-2-deoxystreptamine antibiotic.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processAntibiotic resistance

Names & Taxonomyi

Protein namesi
Recommended name:
Aminoglycoside N(3)-acetyltransferase IX (EC:2.3.1.81)
Alternative name(s):
ACC(3)-IX
Aminocyclitol 3-N-acetyltransferase type IX
Gene namesi
Name:aacC9
OrganismiMicromonospora chalcea
Taxonomic identifieri1874 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicromonosporalesMicromonosporaceaeMicromonospora

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000685511 – 281Aminoglycoside N(3)-acetyltransferase IXAdd BLAST281

Structurei

3D structure databases

ProteinModelPortaliP29810.
SMRiP29810.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00662.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiView protein in InterPro
IPR029058. AB_hydrolase.
IPR003679. Amioglycoside_AcTrfase.
IPR028345. Antibiotic_NAT-like.
PANTHERiPTHR11104. PTHR11104. 1 hit.
PfamiView protein in Pfam
PF02522. Antibiotic_NAT. 1 hit.
SUPFAMiSSF110710. SSF110710. 1 hit.

Sequencei

Sequence statusi: Complete.

P29810-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEMSLLNHS GGPVTRSRIK HDLADLGLKD GDVVIFHTRM SAIGYVAGGT
60 70 80 90 100
QTIIGALLDV VGARGTLMVP CGWNNAPPYD FLDWPRDWQD ALRAEHPAYD
110 120 130 140 150
PDLSEADYNN GRLPEALPRW PGAIRSRHPD ASFAALGPAA AELMAEHPWD
160 170 180 190 200
HPHGPDTPLA RLIAHSGRVL LLGAPLDTMT LLHHAEALAD VRSKRFVTYE
210 220 230 240 250
QPILVNGQRV WRQFRDIDSE EGAFDYSTVR RGVEPFEAIA RDMLSAGIGR
260 270 280
QGRVGAADSY LFDAGPVFNF AINWIEAKLK R
Length:281
Mass (Da):30,989
Last modified:April 1, 1993 - v1
Checksum:iEB62D6B086F7F9E4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M55427 Genomic DNA. Translation: AAA25334.1.
PIRiJE0418.
RefSeqiWP_063840269.1. NG_047255.1.

Genome annotation databases

KEGGiag:AAA25334.

Similar proteinsi

Entry informationi

Entry nameiAACC9_MICCH
AccessioniPrimary (citable) accession number: P29810
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: October 25, 2017
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families