P29694 (EF1G_RABIT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor 1-gamma
Short name=EF-1-gamma

Alternative name(s):
eEF-1B gamma

Gene names

Name:

EEF1G

Organism

Oryctolagus cuniculus (Rabbit) [Complete proteome]

Taxonomic identifier

9986 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Lagomorpha › Leporidae › Oryctolagus

Protein attributes

Sequence length	437 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
PTM	Acetylation Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 437	436	Elongation factor 1-gamma		PRO_0000208816
Regions
	Domain	2 – 87	86	GST N-terminal
	Domain	88 – 216	129	GST C-terminal
	Domain	276 – 437	162	EF-1-gamma C-terminal
Amino acid modifications
	Modified residue	2	1	N-acetylalanine By similarity
	Modified residue	43	1	Phosphothreonine By similarity
	Modified residue	46	1	Phosphothreonine By similarity
	Modified residue	132	1	N6-acetyllysine By similarity
	Modified residue	147	1	N6-acetyllysine By similarity
	Modified residue	434	1	N6-acetyllysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P29694 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: DDC2864547C1FBFE	FASTA	437	50,049
	10 20 30 40 50 60 MAAGTLYTYP ENWRAFKALI AAQYSGAQVR VLSAPPHFHF GQTNRTPEFL RKFPAGKVPA 70 80 90 100 110 120 FEGDDGFCVF ESNAIAYYVS NEELRGSTPE AAAQVVQWVS FADSDIVPPA STWVFPTLGI 130 140 150 160 170 180 MHHNKQATEN AKEEVKRILG LLDAHLKTRT FLVGERVTLA DITVVCTLLW LYKQVLEPSF 190 200 210 220 230 240 RQAFPNTNRW FLTCINQPQF RAVLGEVKLC EKMAQFDAKK FAESQPKKDT PRKEKGSREE 250 260 270 280 290 300 KQKPQAERKE EKKAAAPAPE EEMDECEQAL AAEPKAKDPF AHLPKSTFVL DEFKRKYSNE 310 320 330 340 350 360 DTLSVALPYF WEHFDKDGWS LWYAEYRFPE ELTQTFMSCN LITGMFQRLD KLRKNAFASV 370 380 390 400 410 420 ILFGTNNSSS ISGIWVFRGQ ELAFPLSPDW QVDYESYTWR KLDPSSEETQ TLVREYFAWE 430 GAFQHVGKAF NQGKVFK

References

[1]	"Nucleotide sequence of a rabbit cDNA encoding elongation factor 1 gamma." Sheu G.-T., Traugh J.A. Nucleic Acids Res. 20:5849-5849(1992) [PubMed: 1454551] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: New Zealand white. Tissue: Spleen.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X68142 mRNA. Translation: CAA48242.1.
PIR	S26649.
RefSeq	NP_001095173.1. NM_001101703.1.
UniGene	Ocu.6252.
3D structure databases
ProteinModelPortal	P29694.
SMR	P29694. Positions 276-437.
ModBase	Search...
Protein-protein interaction databases
STRING	P29694.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	100009282.
Organism-specific databases
CTD	1937.
Phylogenomic databases
GeneTree	ENSGT00390000007552.
HOVERGEN	HBG051444.
OrthoDB	EOG43JC4V.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012336. Thioredoxin-like_fold. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit. SSF89942. Transl_elong_EF1_G_con. 1 hit.
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_RABIT

Accession

Primary (citable) accession number: P29694

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	January 23, 2007
Last modified:	November 16, 2011
This is version 80 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program