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Protein

Elongation factor 1-delta

Gene

EEF1D

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.
Isoform 2: Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).

GO - Molecular functioni

  • activating transcription factor binding Source: UniProtKB
  • cadherin binding involved in cell-cell adhesion Source: BHF-UCL
  • DNA binding Source: UniProtKB
  • heat shock protein binding Source: UniProtKB
  • signal transducer activity Source: UniProtKB
  • translation elongation factor activity Source: UniProtKB-KW
  • translation factor activity, RNA binding Source: ProtInc

GO - Biological processi

  • cellular response to ionizing radiation Source: UniProtKB
  • mRNA transcription Source: UniProtKB
  • positive regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
  • regulation of cell death Source: UniProtKB
  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: UniProtKB-KW
  • translational elongation Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciZFISH:ENSG00000104529-MONOMER.
ReactomeiR-HSA-156842. Eukaryotic Translation Elongation.
SIGNORiP29692.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor 1-delta
Short name:
EF-1-delta
Alternative name(s):
Antigen NY-CO-4
Gene namesi
Name:EEF1D
Synonyms:EF1D
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

HGNCiHGNC:3211. EEF1D.

Subcellular locationi

Isoform 2 :
  • Nucleus 1 Publication

GO - Cellular componenti

  • cell-cell adherens junction Source: BHF-UCL
  • cytoplasm Source: UniProtKB
  • cytosol Source: Reactome
  • eukaryotic translation elongation factor 1 complex Source: ProtInc
  • nucleolus Source: HPA
  • nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

DisGeNETi1936.
OpenTargetsiENSG00000104529.
ENSG00000273594.
PharmGKBiPA27647.

Polymorphism and mutation databases

BioMutaiEEF1D.
DMDMi20141357.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources1 Publication
ChainiPRO_00001550462 – 281Elongation factor 1-deltaAdd BLAST280

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineCombined sources1 Publication1
Modified residuei17N6-acetyllysineCombined sources1
Modified residuei37PhosphoserineCombined sources1
Modified residuei44PhosphoserineCombined sources1
Modified residuei60PhosphoserineCombined sources1
Modified residuei73PhosphothreonineCombined sources1
Modified residuei86PhosphoserineCombined sources1
Modified residuei106PhosphoserineBy similarity1
Modified residuei107N6-acetyllysineCombined sources1
Modified residuei117N6-acetyllysine; alternateCombined sources1
Modified residuei117N6-succinyllysine; alternateBy similarity1
Modified residuei119PhosphoserineCombined sources1
Modified residuei129PhosphothreonineCombined sources1
Modified residuei133PhosphoserineCombined sources1
Modified residuei147PhosphothreonineCombined sources1
Modified residuei162Phosphoserine; by CK2Combined sources1 Publication1
Isoform 3 (identifier: P29692-3)
Modified residuei40PhosphoserineCombined sources1
Isoform 2 (identifier: P29692-2)
Modified residuei91PhosphoserineCombined sourcesCurated1
Modified residuei94PhosphoserineCombined sourcesCurated1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiP29692.
MaxQBiP29692.
PaxDbiP29692.
PeptideAtlasiP29692.
PRIDEiP29692.
TopDownProteomicsiP29692-1. [P29692-1]
P29692-3. [P29692-3]
P29692-4. [P29692-4]

2D gel databases

OGPiP29692.

PTM databases

iPTMnetiP29692.
PhosphoSitePlusiP29692.
SwissPalmiP29692.

Expressioni

Tissue specificityi

Isoform 2 is specifically expressed in brain, cerebellum and testis.

Inductioni

By homocysteine (HC), may mediate accelerated synthesis of free thiol-containing proteins in response to HC-induced oxidative stress. Also induced following exposure to ionizing radiation.2 Publications

Gene expression databases

BgeeiENSG00000104529.
CleanExiHS_EEF1D.
ExpressionAtlasiP29692. baseline and differential.
GenevisibleiP29692. HS.

Organism-specific databases

HPAiHPA045101.
HPA051002.

Interactioni

Subunit structurei

EF-1 is composed of 4 subunits: alpha, beta, delta isoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2.

Binary interactionsi

WithEntry#Exp.IntActNotes
ARHGAP21Q5T5U32EBI-358607,EBI-1642518
ATG7O953522EBI-358607,EBI-987834
CAMSAP2Q08AD12EBI-358607,EBI-1051869
EEF1GP266413EBI-358607,EBI-351467
EEF1GP26641-23EBI-358607,EBI-10177695
ERP27Q96DN03EBI-358607,EBI-953772
MAXP612442EBI-358607,EBI-751711
PAQ670202EBI-358607,EBI-11514477From a different organism.
SIAH1Q8IUQ44EBI-358607,EBI-747107
TPT1P136933EBI-358607,EBI-1783169

GO - Molecular functioni

  • activating transcription factor binding Source: UniProtKB
  • cadherin binding involved in cell-cell adhesion Source: BHF-UCL
  • heat shock protein binding Source: UniProtKB

Protein-protein interaction databases

BioGridi108256. 126 interactors.
IntActiP29692. 87 interactors.
MINTiMINT-1139610.
STRINGi9606.ENSP00000391944.

Structurei

Secondary structure

1281
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi153 – 157Combined sources5
Beta strandi159 – 161Combined sources3
Beta strandi162 – 165Combined sources4
Helixi169 – 185Combined sources17
Turni187 – 190Combined sources4
Beta strandi195 – 206Combined sources12
Helixi211 – 219Combined sources9
Beta strandi226 – 235Combined sources10
Beta strandi237 – 239Combined sources3
Beta strandi241 – 250Combined sources10
Turni251 – 253Combined sources3
Helixi256 – 265Combined sources10
Helixi266 – 268Combined sources3
Beta strandi270 – 280Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MVMNMR-A153-192[»]
2MVNNMR-A153-192[»]
2N51NMR-A153-281[»]
ProteinModelPortaliP29692.
SMRiP29692.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni80 – 115Leucine-zipperAdd BLAST36
Regioni173 – 281Catalytic (GEF)Add BLAST109

Sequence similaritiesi

Belongs to the EF-1-beta/EF-1-delta family.Curated

Phylogenomic databases

eggNOGiKOG1668. Eukaryota.
COG2092. LUCA.
GeneTreeiENSGT00390000011747.
HOGENOMiHOG000207272.
HOVERGENiHBG000787.
InParanoidiP29692.
KOiK15410.
PhylomeDBiP29692.
TreeFamiTF313134.

Family and domain databases

CDDicd00292. EF1B. 1 hit.
Gene3Di3.30.70.60. 1 hit.
InterProiIPR018940. EF-1_beta_acid_region_euk.
IPR014038. EF1B_bsu/dsu_GNE.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
IPR001326. Transl_elong_EF1B_B/D_CS.
[Graphical view]
PfamiPF10587. EF-1_beta_acid. 1 hit.
PF00736. EF1_GNE. 1 hit.
[Graphical view]
SMARTiSM01182. EF-1_beta_acid. 1 hit.
SM00888. EF1_GNE. 1 hit.
[Graphical view]
SUPFAMiSSF54984. SSF54984. 1 hit.
PROSITEiPS00824. EF1BD_1. 1 hit.
PS00825. EF1BD_2. 1 hit.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P29692-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MATNFLAHEK IWFDKFKYDD AERRFYEQMN GPVAGASRQE NGASVILRDI
60 70 80 90 100
ARARENIQKS LAGSSGPGAS SGTSGDHGEL VVRIASLEVE NQSLRGVVQE
110 120 130 140 150
LQQAISKLEA RLNVLEKSSP GHRATAPQTQ HVSPMRQVEP PAKKPATPAE
160 170 180 190 200
DDEDDDIDLF GSDNEEEDKE AAQLREERLR QYAEKKAKKP ALVAKSSILL
210 220 230 240 250
DVKPWDDETD MAQLEACVRS IQLDGLVWGA SKLVPVGYGI RKLQIQCVVE
260 270 280
DDKVGTDLLE EEITKFEEHV QSVDIAAFNK I
Length:281
Mass (Da):31,122
Last modified:January 23, 2007 - v5
Checksum:iCE778D6D5D09BD6C
GO
Isoform 2 (identifier: P29692-2) [UniParc]FASTAAdd to basket
Also known as: eEF1BdeltaL

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MRSGKASCTL...VSSLRPNRKM

Show »
Length:647
Mass (Da):71,408
Checksum:iA4CADBF40FCFCC09
GO
Isoform 3 (identifier: P29692-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     40-63: Missing.

Show »
Length:257
Mass (Da):28,558
Checksum:iE38BA673BE18FBE5
GO
Isoform 4 (identifier: P29692-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     78-96: Missing.

Note: No experimental confirmation available.
Show »
Length:262
Mass (Da):29,071
Checksum:i7F9682E53B69BC17
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti34A → R in CAA79716 (PubMed:8334168).Curated1
Sequence conflicti44S → T in CAA79716 (PubMed:8334168).Curated1
Sequence conflicti209T → A in BAG56855 (PubMed:14702039).Curated1
Isoform 2 (identifier: P29692-2)
Sequence conflicti189D → E in AAP35906 (Ref. 3) Combined sourcesCurated1
Sequence conflicti189D → E in EAW82228 (PubMed:14702039).Combined sourcesCurated1
Sequence conflicti189D → E in AAH07847 (PubMed:16421571).Combined sourcesCurated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0378841M → MRSGKASCTLETVWEDKHKY EEAERRFYEHEATQAAASAQ QLPAEGPAMNGPGQDDPEDA DEAEAPDGGSRRDPRKSQDS RKPLQKKRKRSPKSGLGPAD LALLGLSAERVWLDKSLFDQ AESSYRQKLADVAAQAAWPP ALAPWGLCTHGNQVACHHVT WGIWVNKSSFDQAERAFVEW SQALLLAPDGSRRQGTPNTG QQVAVPDLAHQPSPPVNGQP PLGSLQALVREVWLEKPRYD AAERGFYEALFDGHPPGKVR LQERAGLAEGARRGRRDRRG RNILGNKRAGLRRADGEAPS ALPYCYFLQKDAEAPWLSKP AYDSAECRHHAAEALRVAWC LEAASLSHRPGPRSGLSVSS LRPNRKM in isoform 2. 2 Publications1
Alternative sequenceiVSP_04381240 – 63Missing in isoform 3. 1 PublicationAdd BLAST24
Alternative sequenceiVSP_04596078 – 96Missing in isoform 4. 1 PublicationAdd BLAST19

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z21507 mRNA. Translation: CAA79716.1.
BT007242 mRNA. Translation: AAP35906.1.
AK293339 mRNA. Translation: BAG56855.1.
AC067930 Genomic DNA. No translation available.
CH471162 Genomic DNA. Translation: EAW82227.1.
CH471162 Genomic DNA. Translation: EAW82228.1.
CH471162 Genomic DNA. Translation: EAW82229.1.
CH471162 Genomic DNA. Translation: EAW82230.1.
CH471162 Genomic DNA. Translation: EAW82232.1.
BC007847 mRNA. Translation: AAH07847.1.
BC009907 mRNA. Translation: AAH09907.1.
BC012819 mRNA. Translation: AAH12819.1.
BC062535 mRNA. Translation: AAH62535.1.
BC094806 mRNA. Translation: AAH94806.1.
CCDSiCCDS47930.1. [P29692-3]
CCDS56559.1. [P29692-4]
CCDS6404.1. [P29692-2]
CCDS6405.1. [P29692-1]
PIRiS34626.
RefSeqiNP_001123525.2. NM_001130053.3.
NP_001123527.1. NM_001130055.3. [P29692-1]
NP_001123528.1. NM_001130056.3. [P29692-3]
NP_001123529.1. NM_001130057.3. [P29692-1]
NP_001182132.1. NM_001195203.2. [P29692-4]
NP_001276879.1. NM_001289950.2. [P29692-1]
NP_001304672.1. NM_001317743.2. [P29692-3]
NP_001317575.1. NM_001330646.1.
NP_001951.2. NM_001960.5. [P29692-1]
NP_115754.3. NM_032378.5.
XP_005250880.1. XM_005250823.1. [P29692-2]
XP_006716585.1. XM_006716522.1. [P29692-2]
XP_006716586.1. XM_006716523.1. [P29692-2]
XP_006716587.1. XM_006716524.1. [P29692-2]
XP_006716588.1. XM_006716525.1. [P29692-1]
XP_011515207.1. XM_011516905.2. [P29692-2]
XP_011515208.1. XM_011516906.2. [P29692-2]
XP_016868659.1. XM_017013170.1. [P29692-2]
UniGeneiHs.333388.
Hs.686554.
Hs.703306.

Genome annotation databases

EnsembliENST00000317198; ENSP00000317399; ENSG00000104529. [P29692-1]
ENST00000395119; ENSP00000378551; ENSG00000104529. [P29692-1]
ENST00000419152; ENSP00000388261; ENSG00000104529. [P29692-1]
ENST00000423316; ENSP00000410059; ENSG00000104529. [P29692-2]
ENST00000442189; ENSP00000391944; ENSG00000104529. [P29692-2]
ENST00000524624; ENSP00000435697; ENSG00000104529. [P29692-3]
ENST00000526838; ENSP00000436507; ENSG00000104529. [P29692-4]
ENST00000528610; ENSP00000431763; ENSG00000104529. [P29692-3]
ENST00000529272; ENSP00000434872; ENSG00000104529. [P29692-1]
ENST00000614575; ENSP00000478340; ENSG00000273594. [P29692-1]
ENST00000615067; ENSP00000479653; ENSG00000273594. [P29692-1]
ENST00000615698; ENSP00000483527; ENSG00000273594. [P29692-1]
ENST00000619144; ENSP00000477608; ENSG00000273594. [P29692-2]
ENST00000620155; ENSP00000480505; ENSG00000273594. [P29692-2]
ENST00000631698; ENSP00000488672; ENSG00000273594. [P29692-4]
ENST00000632587; ENSP00000487680; ENSG00000273594. [P29692-1]
ENST00000632675; ENSP00000488026; ENSG00000273594. [P29692-3]
ENST00000632965; ENSP00000488275; ENSG00000273594. [P29692-3]
GeneIDi1936.
KEGGihsa:1936.
UCSCiuc003yyr.4. human. [P29692-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z21507 mRNA. Translation: CAA79716.1.
BT007242 mRNA. Translation: AAP35906.1.
AK293339 mRNA. Translation: BAG56855.1.
AC067930 Genomic DNA. No translation available.
CH471162 Genomic DNA. Translation: EAW82227.1.
CH471162 Genomic DNA. Translation: EAW82228.1.
CH471162 Genomic DNA. Translation: EAW82229.1.
CH471162 Genomic DNA. Translation: EAW82230.1.
CH471162 Genomic DNA. Translation: EAW82232.1.
BC007847 mRNA. Translation: AAH07847.1.
BC009907 mRNA. Translation: AAH09907.1.
BC012819 mRNA. Translation: AAH12819.1.
BC062535 mRNA. Translation: AAH62535.1.
BC094806 mRNA. Translation: AAH94806.1.
CCDSiCCDS47930.1. [P29692-3]
CCDS56559.1. [P29692-4]
CCDS6404.1. [P29692-2]
CCDS6405.1. [P29692-1]
PIRiS34626.
RefSeqiNP_001123525.2. NM_001130053.3.
NP_001123527.1. NM_001130055.3. [P29692-1]
NP_001123528.1. NM_001130056.3. [P29692-3]
NP_001123529.1. NM_001130057.3. [P29692-1]
NP_001182132.1. NM_001195203.2. [P29692-4]
NP_001276879.1. NM_001289950.2. [P29692-1]
NP_001304672.1. NM_001317743.2. [P29692-3]
NP_001317575.1. NM_001330646.1.
NP_001951.2. NM_001960.5. [P29692-1]
NP_115754.3. NM_032378.5.
XP_005250880.1. XM_005250823.1. [P29692-2]
XP_006716585.1. XM_006716522.1. [P29692-2]
XP_006716586.1. XM_006716523.1. [P29692-2]
XP_006716587.1. XM_006716524.1. [P29692-2]
XP_006716588.1. XM_006716525.1. [P29692-1]
XP_011515207.1. XM_011516905.2. [P29692-2]
XP_011515208.1. XM_011516906.2. [P29692-2]
XP_016868659.1. XM_017013170.1. [P29692-2]
UniGeneiHs.333388.
Hs.686554.
Hs.703306.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2MVMNMR-A153-192[»]
2MVNNMR-A153-192[»]
2N51NMR-A153-281[»]
ProteinModelPortaliP29692.
SMRiP29692.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi108256. 126 interactors.
IntActiP29692. 87 interactors.
MINTiMINT-1139610.
STRINGi9606.ENSP00000391944.

PTM databases

iPTMnetiP29692.
PhosphoSitePlusiP29692.
SwissPalmiP29692.

Polymorphism and mutation databases

BioMutaiEEF1D.
DMDMi20141357.

2D gel databases

OGPiP29692.

Proteomic databases

EPDiP29692.
MaxQBiP29692.
PaxDbiP29692.
PeptideAtlasiP29692.
PRIDEiP29692.
TopDownProteomicsiP29692-1. [P29692-1]
P29692-3. [P29692-3]
P29692-4. [P29692-4]

Protocols and materials databases

DNASUi1936.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000317198; ENSP00000317399; ENSG00000104529. [P29692-1]
ENST00000395119; ENSP00000378551; ENSG00000104529. [P29692-1]
ENST00000419152; ENSP00000388261; ENSG00000104529. [P29692-1]
ENST00000423316; ENSP00000410059; ENSG00000104529. [P29692-2]
ENST00000442189; ENSP00000391944; ENSG00000104529. [P29692-2]
ENST00000524624; ENSP00000435697; ENSG00000104529. [P29692-3]
ENST00000526838; ENSP00000436507; ENSG00000104529. [P29692-4]
ENST00000528610; ENSP00000431763; ENSG00000104529. [P29692-3]
ENST00000529272; ENSP00000434872; ENSG00000104529. [P29692-1]
ENST00000614575; ENSP00000478340; ENSG00000273594. [P29692-1]
ENST00000615067; ENSP00000479653; ENSG00000273594. [P29692-1]
ENST00000615698; ENSP00000483527; ENSG00000273594. [P29692-1]
ENST00000619144; ENSP00000477608; ENSG00000273594. [P29692-2]
ENST00000620155; ENSP00000480505; ENSG00000273594. [P29692-2]
ENST00000631698; ENSP00000488672; ENSG00000273594. [P29692-4]
ENST00000632587; ENSP00000487680; ENSG00000273594. [P29692-1]
ENST00000632675; ENSP00000488026; ENSG00000273594. [P29692-3]
ENST00000632965; ENSP00000488275; ENSG00000273594. [P29692-3]
GeneIDi1936.
KEGGihsa:1936.
UCSCiuc003yyr.4. human. [P29692-1]

Organism-specific databases

CTDi1936.
DisGeNETi1936.
GeneCardsiEEF1D.
H-InvDBHIX0034587.
HGNCiHGNC:3211. EEF1D.
HPAiHPA045101.
HPA051002.
MIMi130592. gene.
neXtProtiNX_P29692.
OpenTargetsiENSG00000104529.
ENSG00000273594.
PharmGKBiPA27647.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1668. Eukaryota.
COG2092. LUCA.
GeneTreeiENSGT00390000011747.
HOGENOMiHOG000207272.
HOVERGENiHBG000787.
InParanoidiP29692.
KOiK15410.
PhylomeDBiP29692.
TreeFamiTF313134.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000104529-MONOMER.
ReactomeiR-HSA-156842. Eukaryotic Translation Elongation.
SIGNORiP29692.

Miscellaneous databases

ChiTaRSiEEF1D. human.
GeneWikiiEEF1D.
GenomeRNAii1936.
PROiP29692.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000104529.
CleanExiHS_EEF1D.
ExpressionAtlasiP29692. baseline and differential.
GenevisibleiP29692. HS.

Family and domain databases

CDDicd00292. EF1B. 1 hit.
Gene3Di3.30.70.60. 1 hit.
InterProiIPR018940. EF-1_beta_acid_region_euk.
IPR014038. EF1B_bsu/dsu_GNE.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
IPR001326. Transl_elong_EF1B_B/D_CS.
[Graphical view]
PfamiPF10587. EF-1_beta_acid. 1 hit.
PF00736. EF1_GNE. 1 hit.
[Graphical view]
SMARTiSM01182. EF-1_beta_acid. 1 hit.
SM00888. EF1_GNE. 1 hit.
[Graphical view]
SUPFAMiSSF54984. SSF54984. 1 hit.
PROSITEiPS00824. EF1BD_1. 1 hit.
PS00825. EF1BD_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiEF1D_HUMAN
AccessioniPrimary (citable) accession number: P29692
Secondary accession number(s): B4DDU4
, D3DWK3, E9PBQ9, Q4VBZ6, Q969J1, Q96I38
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 183 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.