ID   AHT1_YEAST              Reviewed;         182 AA.
AC   P29589; A0A1S0SZW8; P38807;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   24-JAN-2024, entry version 98.
DE   RecName: Full=Hexose transport activator protein;
GN   Name=AHT1; OrderedLocusNames=YHR093W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=MC 971 B;
RA   Oezcan S., Ciriacy M.;
RL   Submitted (MAY-1991) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   FUNCTION.
RX   PubMed=8366037; DOI=10.1128/jb.175.17.5520-5528.1993;
RA   Oezcan S., Freidel K., Leuker A., Ciriacy M.;
RT   "Glucose uptake and catabolite repression in dominant HTR1 mutants of
RT   Saccharomyces cerevisiae.";
RL   J. Bacteriol. 175:5520-5528(1993).
RN   [6]
RP   IDENTIFICATION AS PROBABLE DUBIOUS PREDICTION.
RX   PubMed=7982576; DOI=10.1093/genetics/137.4.957;
RA   Theodoris G., Fong N.M., Coons D.M., Bisson L.F.;
RT   "High-copy suppression of glucose transport defects by HXT4 and regulatory
RT   elements in the promoters of the HXT genes in Saccharomyces cerevisiae.";
RL   Genetics 137:957-966(1994).
CC   -!- FUNCTION: Multicopy expression suppresses glucose-uptake defects in
CC       various yeast mutants. {ECO:0000269|PubMed:8366037}.
CC   -!- CAUTION: Present in the 5'-UTR of low-affinity glucose transporter
CC       HXT4, the multicopy suppression phenotype is probably due to the
CC       presence of an HXT4 regulatory element in this region.
CC       {ECO:0000305|PubMed:7982576}.
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DR   EMBL; X59464; CAA42071.1; -; Genomic_DNA.
DR   EMBL; U00060; AAB68925.1; -; Genomic_DNA.
DR   EMBL; AY693252; AAT93271.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA80259.1; -; Genomic_DNA.
DR   PIR; S17005; S17005.
DR   AlphaFoldDB; P29589; -.
DR   STRING; 4932.YHR093W; -.
DR   PaxDb; 4932-YHR093W; -.
DR   EnsemblFungi; YHR093W_mRNA; YHR093W; YHR093W.
DR   AGR; SGD:S000001135; -.
DR   SGD; S000001135; AHT1.
DR   HOGENOM; CLU_134598_0_0_1; -.
DR   InParanoid; P29589; -.
DR   OMA; DIFLPCF; -.
DR   PRO; PR:P29589; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P29589; Protein.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..182
FT                   /note="Hexose transport activator protein"
FT                   /id="PRO_0000064511"
FT   REGION          46..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   182 AA;  19776 MW;  7B0723BAA1066713 CRC64;
     MDCKIKAAGK NSGIFHEGGT KSSKSFLTVF IRSVFPLSPS FPAGGGIWGP MEKKPGGVGK
     KKGSEKKTAQ GNIFFSTERD AGQEKCGILY KHCFSILYGF FWKKADKPKE KTGNGSGLGI
     VFPIGQKKIP EPADSDIFLP CFRYAAASDF TKAKRFLVEI TAVYWVSLEA QPSSASCLFI
     LI
//