P29589 (AHT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative hexose transport activator protein

Gene names

Name:	AHT1
Ordered Locus Names:	YHR093W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › Saccharomyces cerevisiae

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Function	Multicopy expression suppresses glucose-uptake defects in various yeast mutants. Ref.4
Caution	Product of a dubious gene prediction. Present in the 5'-UTR of low-affinity glucose transporter HXT4, the multicopy suppression phenotype is probably due to the presence of an HXT4 regulatory element in this region.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 182	182	Putative hexose transport activator protein		PRO_0000064511

Sequences

	Sequence		Length	Mass (Da)
	P29589 [UniParc]. Last modified April 1, 1993. Version 1. Checksum: 7B0723BAA1066713	FASTA	182	19,776
	10 20 30 40 50 60 MDCKIKAAGK NSGIFHEGGT KSSKSFLTVF IRSVFPLSPS FPAGGGIWGP MEKKPGGVGK 70 80 90 100 110 120 KKGSEKKTAQ GNIFFSTERD AGQEKCGILY KHCFSILYGF FWKKADKPKE KTGNGSGLGI 130 140 150 160 170 180 VFPIGQKKIP EPADSDIFLP CFRYAAASDF TKAKRFLVEI TAVYWVSLEA QPSSASCLFI LI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Oezcan S., Ciriacy M. Submitted (MAY-1991) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: MC 971 B.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[4]	"Glucose uptake and catabolite repression in dominant HTR1 mutants of Saccharomyces cerevisiae." Oezcan S., Freidel K., Leuker A., Ciriacy M. J. Bacteriol. 175:5520-5528(1993) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION.
[5]	"High-copy suppression of glucose transport defects by HXT4 and regulatory elements in the promoters of the HXT genes in Saccharomyces cerevisiae." Theodoris G., Fong N.M., Coons D.M., Bisson L.F. Genetics 137:957-966(1994) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION AS PROBABLE DUBIOUS PREDICTION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X59464 Genomic DNA. Translation: CAA42071.1. U00060 Genomic DNA. Translation: AAB68925.1. AY693252 Genomic DNA. Translation: AAT93271.1.
PIR	S17005.
3D structure databases
ProteinModelPortal	P29589.
ModBase	Search...
Protein-protein interaction databases
STRING	4932.YHR093W.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHR093W; YHR093W; YHR093W.
Organism-specific databases
SGD	S000001135. AHT1.
Gene expression databases
Genevestigator	P29589.
GermOnline	YHR093W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

AHT1_YEAST

Accession

Primary (citable) accession number: P29589
Secondary accession number(s): P38807

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 1, 1993
Last sequence update:	April 1, 1993
Last modified:	April 3, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program