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P29589 (AHT1_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative hexose transport activator protein
Gene names
Name:AHT1
Ordered Locus Names:YHR093W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length182 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Multicopy expression suppresses glucose-uptake defects in various yeast mutants. Ref.5

Caution

Product of a dubious gene prediction. Present in the 5'-UTR of low-affinity glucose transporter HXT4, the multicopy suppression phenotype is probably due to the presence of an HXT4 regulatory element in this region.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 182182Putative hexose transport activator protein
PRO_0000064511

Sequences

Sequence LengthMass (Da)Tools
P29589 [UniParc].

Last modified April 1, 1993. Version 1.
Checksum: 7B0723BAA1066713

FASTA18219,776
        10         20         30         40         50         60 
MDCKIKAAGK NSGIFHEGGT KSSKSFLTVF IRSVFPLSPS FPAGGGIWGP MEKKPGGVGK 

        70         80         90        100        110        120 
KKGSEKKTAQ GNIFFSTERD AGQEKCGILY KHCFSILYGF FWKKADKPKE KTGNGSGLGI 

       130        140        150        160        170        180 
VFPIGQKKIP EPADSDIFLP CFRYAAASDF TKAKRFLVEI TAVYWVSLEA QPSSASCLFI 


LI 

« Hide

References

« Hide 'large scale' references
[1]Oezcan S., Ciriacy M.
Submitted (MAY-1991) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: MC 971 B.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII."
Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. expand/collapse author list , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M.
Science 265:2077-2082(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]"The reference genome sequence of Saccharomyces cerevisiae: Then and now."
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.
G3 (Bethesda) 4:389-398(2014) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Glucose uptake and catabolite repression in dominant HTR1 mutants of Saccharomyces cerevisiae."
Oezcan S., Freidel K., Leuker A., Ciriacy M.
J. Bacteriol. 175:5520-5528(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
[6]"High-copy suppression of glucose transport defects by HXT4 and regulatory elements in the promoters of the HXT genes in Saccharomyces cerevisiae."
Theodoris G., Fong N.M., Coons D.M., Bisson L.F.
Genetics 137:957-966(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION AS PROBABLE DUBIOUS PREDICTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59464 Genomic DNA. Translation: CAA42071.1.
U00060 Genomic DNA. Translation: AAB68925.1.
AY693252 Genomic DNA. Translation: AAT93271.1.
BK006934 Genomic DNA. No translation available.
PIRS17005.

3D structure databases

ProteinModelPortalP29589.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4932.YHR093W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYHR093W; YHR093W; YHR093W.

Organism-specific databases

SGDS000001135. AHT1.

Phylogenomic databases

OMAVNTRIHE.
OrthoDBEOG77Q57X.

Gene expression databases

GenevestigatorP29589.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameAHT1_YEAST
AccessionPrimary (citable) accession number: P29589
Secondary accession number(s): P38807
Entry history
Integrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: April 1, 1993
Last modified: May 14, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome VIII

Yeast (Saccharomyces cerevisiae) chromosome VIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD