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P29566

- T2MZ_METTF

UniProt

P29566 - T2MZ_METTF

Protein

Probable type-2 restriction enzyme MthZI

Gene

mthZIR

Organism
Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (01 Apr 1993)
      Previous versions | rss
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    Functioni

    Recognizes the double-stranded sequence CTAG and cleaves after C-1.1 Publication

    Catalytic activityi

    Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.1 Publication

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. Type II site-specific deoxyribonuclease activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    Restriction system

    Protein family/group databases

    REBASEi2204. MthZI.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable type-2 restriction enzyme MthZI (EC:3.1.21.4)
    Short name:
    R.MthZI
    Alternative name(s):
    Endonuclease MthZI
    Type II restriction enzyme MthZI
    Gene namesi
    Name:mthZIR
    Encoded oniPlasmid pFZ10 Publication
    OrganismiMethanothermobacter thermautotrophicus (Methanobacterium thermoformicicum)
    Taxonomic identifieri145262 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanobacteriaMethanobacterialesMethanobacteriaceaeMethanothermobacter

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 202202Probable type-2 restriction enzyme MthZIPRO_0000077340Add
    BLAST

    Family & Domainsi

    Family and domain databases

    InterProiIPR019068. Restrct_endonuc_II_MjaI.
    [Graphical view]
    PfamiPF09568. RE_MjaI. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P29566-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIDNFKEIRL DFKDELKKIT GKEVEFPKYT TQIINLANQN AQGTRPRVVG    50
    QMSDLIHECP DKSYEGWKKW YLEHYSDRIE KATKKISKMI ENMKAAMELI 100
    DEEMIRKWVE DLVITKTAEG LIIQEIILKT IAEEAGLEWR LATSKEESKN 150
    IDGFIGSTPV SIKPMSYESM RPTVREEIDI QTIFYKKPKN SRYLYIYHNL 200
    NI 202
    Length:202
    Mass (Da):23,742
    Last modified:April 1, 1993 - v1
    Checksum:i1AC0274DEC882F49
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X67212 Genomic DNA. Translation: CAA47652.1.
    X68367 Genomic DNA. Translation: CAA48446.1.
    PIRiS26074.
    RefSeqiNP_039774.1. NC_001337.1.
    WP_010889861.1. NC_001337.1.

    Genome annotation databases

    GeneIDi3355220.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X67212 Genomic DNA. Translation: CAA47652.1 .
    X68367 Genomic DNA. Translation: CAA48446.1 .
    PIRi S26074.
    RefSeqi NP_039774.1. NC_001337.1.
    WP_010889861.1. NC_001337.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 2204. MthZI.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3355220.

    Family and domain databases

    InterProi IPR019068. Restrct_endonuc_II_MjaI.
    [Graphical view ]
    Pfami PF09568. RE_MjaI. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of the CTAG-recognizing restriction-modification systems MthZI and MthFI from Methanobacterium thermoformicicum and characterization of the plasmid-encoded mthZIM gene."
      Noelling J., de Vos W.M.
      Nucleic Acids Res. 20:5047-5052(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, CATALYTIC ACTIVITY.
      Strain: DSM 3720 / Z-245.
    2. "Modular organization of related Archaeal plasmids encoding different restriction-modification systems in Methanobacterium thermoformicicum."
      Noelling J., van Eeden F.J.M., Eggen R.I.L., de Vos W.M.
      Nucleic Acids Res. 20:6501-6507(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: DSM 3720 / Z-245.

    Entry informationi

    Entry nameiT2MZ_METTF
    AccessioniPrimary (citable) accession number: P29566
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 1, 1993
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Plasmid

    Documents

    1. Restriction enzymes and methylases
      Classification of restriction enzymes and methylases and list of entries

    External Data

    Dasty 3